BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

72 related articles for article (PubMed ID: 10512727)

  • 21. Site-directed mutagenesis of the putative distal helix of peroxygenase cytochrome P450.
    Matsunaga I; Ueda A; Sumimoto T; Ichihara K; Ayata M; Ogura H
    Arch Biochem Biophys; 2001 Oct; 394(1):45-53. PubMed ID: 11566026
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Catalytic mechanism of inulinase from Arthrobacter sp. S37.
    Kim KY; Nascimento AS; Golubev AM; Polikarpov I; Kim CS; Kang SI; Kim SI
    Biochem Biophys Res Commun; 2008 Jul; 371(4):600-5. PubMed ID: 18395004
    [TBL] [Abstract][Full Text] [Related]  

  • 23. On the catalytic role of the conserved active site residue His466 of choline oxidase.
    Ghanem M; Gadda G
    Biochemistry; 2005 Jan; 44(3):893-904. PubMed ID: 15654745
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Dual roles of Lys(57) at the dimer interface of human mitochondrial NAD(P)+-dependent malic enzyme.
    Hsieh JY; Liu JH; Fang YW; Hung HC
    Biochem J; 2009 May; 420(2):201-9. PubMed ID: 19236308
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Thermodynamic cycle analysis and inhibitor design against beta-lactamase.
    Roth TA; Minasov G; Morandi S; Prati F; Shoichet BK
    Biochemistry; 2003 Dec; 42(49):14483-91. PubMed ID: 14661960
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Functional and structural changes due to a serine to alanine mutation in the active-site flap of enolase.
    Poyner RR; Larsen TM; Wong SW; Reed GH
    Arch Biochem Biophys; 2002 May; 401(2):155-63. PubMed ID: 12054465
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Improved catalytic properties of halohydrin dehalogenase by modification of the halide-binding site.
    Tang L; Torres Pazmiño DE; Fraaije MW; de Jong RM; Dijkstra BW; Janssen DB
    Biochemistry; 2005 May; 44(17):6609-18. PubMed ID: 15850394
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Preliminary crystallographic studies on scytalone dehydratase from Magnaporthe grisea.
    Lundqvist T; Weber PC; Hodge CN; Braswell EH; Rice J; Pierce J
    J Mol Biol; 1993 Aug; 232(3):999-1002. PubMed ID: 8355286
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Synthesis and biological evaluation of new nanomolar competitive inhibitors of Helicobacter pylori type II dehydroquinase. Structural details of the role of the aromatic moieties with essential residues.
    Prazeres VF; Tizón L; Otero JM; Guardado-Calvo P; Llamas-Saiz AL; van Raaij MJ; Castedo L; Lamb H; Hawkins AR; González-Bello C
    J Med Chem; 2010 Jan; 53(1):191-200. PubMed ID: 19911771
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Binding dynamics of two water molecules constrained within the scytalone dehydratase binding pocket.
    Jordan DB; Basarab GS
    Bioorg Med Chem Lett; 2000 Jan; 10(1):23-6. PubMed ID: 10636235
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Structure-based optimization and biological evaluation of human 20α-hydroxysteroid dehydrogenase (AKR1C1) salicylic acid-based inhibitors.
    El-Kabbani O; Scammells PJ; Day T; Dhagat U; Endo S; Matsunaga T; Soda M; Hara A
    Eur J Med Chem; 2010 Nov; 45(11):5309-17. PubMed ID: 20850205
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Rational design of a scytalone dehydratase-like enzyme using a structurally homologous protein scaffold.
    Nixon AE; Firestine SM; Salinas FG; Benkovic SJ
    Proc Natl Acad Sci U S A; 1999 Mar; 96(7):3568-71. PubMed ID: 10097077
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Tyrosine 110 plays a critical role in regulating the allosteric inhibition of Campylobacter jejuni dihydrodipicolinate synthase by lysine.
    Conly CJ; Skovpen YV; Li S; Palmer DR; Sanders DA
    Biochemistry; 2014 Dec; 53(47):7396-406. PubMed ID: 25369463
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Design of inhibitors of scytalone dehydratase: probing interactions with an asparagine carboxamide.
    Basarab GS; Jordan DB; Gehret TC; Schwartz RS
    Bioorg Med Chem; 2002 Dec; 10(12):4143-54. PubMed ID: 12413868
    [TBL] [Abstract][Full Text] [Related]  

  • 35. High-resolution structures of scytalone dehydratase-inhibitor complexes crystallized at physiological pH.
    Wawrzak Z; Sandalova T; Steffens JJ; Basarab GS; Lundqvist T; Lindqvist Y; Jordan DB
    Proteins; 1999 Jun; 35(4):425-39. PubMed ID: 10382670
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Enzymatic characterization of scytalone dehydratase Val75Met variant found in melanin biosynthesis dehydratase inhibitor (MBI-D) resistant strains of the rice blast fungus.
    Yamada N; Motoyama T; Nakasako M; Kagabu S; Kudo T; Yamaguchi I
    Biosci Biotechnol Biochem; 2004 Mar; 68(3):615-21. PubMed ID: 15056895
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Structure-based design of potent inhibitors of scytalone dehydratase: displacement of a water molecule from the active site.
    Chen JM; Xu SL; Wawrzak Z; Basarab GS; Jordan DB
    Biochemistry; 1998 Dec; 37(51):17735-44. PubMed ID: 9922139
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Crystal structure of scytalone dehydratase--a disease determinant of the rice pathogen, Magnaporthe grisea.
    Lundqvist T; Rice J; Hodge CN; Basarab GS; Pierce J; Lindqvist Y
    Structure; 1994 Oct; 2(10):937-44. PubMed ID: 7866745
    [TBL] [Abstract][Full Text] [Related]  

  • 39. β-Hydroxyacyl-acyl Carrier Protein Dehydratase (FabZ) from Francisella tularensis and Yersinia pestis: Structure Determination, Enzymatic Characterization, and Cross-Inhibition Studies.
    McGillick BE; Kumaran D; Vieni C; Swaminathan S
    Biochemistry; 2016 Feb; 55(7):1091-9. PubMed ID: 26818694
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Probing secondary glutaminyl cyclase (QC) inhibitor interactions applying an in silico-modeling/site-directed mutagenesis approach: implications for drug development.
    Koch B; Buchholz M; Wermann M; Heiser U; Schilling S; Demuth HU
    Chem Biol Drug Des; 2012 Dec; 80(6):937-46. PubMed ID: 22967026
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 4.