BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

158 related articles for article (PubMed ID: 10514520)

  • 1. CIS associates with the interleukin-2 receptor beta chain and inhibits interleukin-2-dependent signaling.
    Aman MJ; Migone TS; Sasaki A; Ascherman DP; Zhu Mh; Soldaini E; Imada K; Miyajima A; Yoshimura A; Leonard WJ
    J Biol Chem; 1999 Oct; 274(42):30266-72. PubMed ID: 10514520
    [TBL] [Abstract][Full Text] [Related]  

  • 2. CIS, a cytokine inducible SH2 protein, is a target of the JAK-STAT5 pathway and modulates STAT5 activation.
    Matsumoto A; Masuhara M; Mitsui K; Yokouchi M; Ohtsubo M; Misawa H; Miyajima A; Yoshimura A
    Blood; 1997 May; 89(9):3148-54. PubMed ID: 9129017
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Delineation of the regions of interleukin-2 (IL-2) receptor beta chain important for association of Jak1 and Jak3. Jak1-independent functional recruitment of Jak3 to Il-2Rbeta.
    Zhu MH; Berry JA; Russell SM; Leonard WJ
    J Biol Chem; 1998 Apr; 273(17):10719-25. PubMed ID: 9553136
    [TBL] [Abstract][Full Text] [Related]  

  • 4. SOCS-3 is tyrosine phosphorylated in response to interleukin-2 and suppresses STAT5 phosphorylation and lymphocyte proliferation.
    Cohney SJ; Sanden D; Cacalano NA; Yoshimura A; Mui A; Migone TS; Johnston JA
    Mol Cell Biol; 1999 Jul; 19(7):4980-8. PubMed ID: 10373548
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Interleukin 9 induces expression of three cytokine signal inhibitors: cytokine-inducible SH2-containing protein, suppressor of cytokine signalling (SOCS)-2 and SOCS-3, but only SOCS-3 overexpression suppresses interleukin 9 signalling.
    Lejeune D; Demoulin JB; Renauld JC
    Biochem J; 2001 Jan; 353(Pt 1):109-116. PubMed ID: 11115404
    [TBL] [Abstract][Full Text] [Related]  

  • 6. JAB/SOCS1/SSI-1 is an interleukin-2-induced inhibitor of IL-2 signaling.
    Sporri B; Kovanen PE; Sasaki A; Yoshimura A; Leonard WJ
    Blood; 2001 Jan; 97(1):221-6. PubMed ID: 11133764
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Suppression of STAT5 functions in liver, mammary glands, and T cells in cytokine-inducible SH2-containing protein 1 transgenic mice.
    Matsumoto A; Seki Y; Kubo M; Ohtsuka S; Suzuki A; Hayashi I; Tsuji K; Nakahata T; Okabe M; Yamada S; Yoshimura A
    Mol Cell Biol; 1999 Sep; 19(9):6396-407. PubMed ID: 10454585
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A new protein containing an SH2 domain that inhibits JAK kinases.
    Endo TA; Masuhara M; Yokouchi M; Suzuki R; Sakamoto H; Mitsui K; Matsumoto A; Tanimura S; Ohtsubo M; Misawa H; Miyazaki T; Leonor N; Taniguchi T; Fujita T; Kanakura Y; Komiya S; Yoshimura A
    Nature; 1997 Jun; 387(6636):921-4. PubMed ID: 9202126
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Prolactin-induced expression of cytokine-inducible SH2 signaling inhibitors in human hematopoietic progenitors.
    Cwikel S; Silvian-Drachsler I; Prolov L; Hooghe-Peters EL; Merchav S
    Exp Hematol; 2001 Aug; 29(8):937-42. PubMed ID: 11495699
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Association of STAT1, STAT3 and STAT5 proteins with the IL-2 receptor involves different subdomains of the IL-2 receptor beta chain.
    Delespine-Carmagnat M; Bouvier G; Bertoglio J
    Eur J Immunol; 2000 Jan; 30(1):59-68. PubMed ID: 10602027
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Transcriptional regulation of the beta-casein gene by cytokines: cross-talk between STAT5 and other signaling molecules.
    Chida D; Wakao H; Yoshimura A; Miyajima A
    Mol Endocrinol; 1998 Nov; 12(11):1792-806. PubMed ID: 9817603
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Distinct tyrosine residues within the interleukin-2 receptor beta chain drive signal transduction specificity, redundancy, and diversity.
    Gaffen SL; Lai SY; Ha M; Liu X; Hennighausen L; Greene WC; Goldsmith MA
    J Biol Chem; 1996 Aug; 271(35):21381-90. PubMed ID: 8702919
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Identification of a variable region within the cytoplasmic tail of the IL-2 receptor beta chain that is required for growth signal transduction.
    Liu KD; Lai SY; Goldsmith MA; Greene WC
    J Biol Chem; 1995 Sep; 270(38):22176-81. PubMed ID: 7545674
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Interleukin-2 (IL-2)-mediated induction of the IL-2 receptor alpha chain gene. Critical role of two functionally redundant tyrosine residues in the IL-2 receptor beta chain cytoplasmic domain and suggestion that these residues mediate more than Stat5 activation.
    Ascherman DP; Migone TS; Friedmann MC; Leonard WJ
    J Biol Chem; 1997 Mar; 272(13):8704-9. PubMed ID: 9079703
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Inhibition of IL-2-induced Jak-STAT signaling by glucocorticoids.
    Bianchi M; Meng C; Ivashkiv LB
    Proc Natl Acad Sci U S A; 2000 Aug; 97(17):9573-8. PubMed ID: 10920190
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Interleukin-6 inhibits hepatic growth hormone signaling via upregulation of Cis and Socs-3.
    Denson LA; Held MA; Menon RK; Frank SJ; Parlow AF; Arnold DL
    Am J Physiol Gastrointest Liver Physiol; 2003 Apr; 284(4):G646-54. PubMed ID: 12519742
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Critical role of the membrane-proximal, proline-rich motif of the interleukin-2 receptor gammac chain in the Jak3-independent signal transduction.
    Tsujino S; Miyazaki T; Kawahara A; Maeda M; Taniguchi T; Fujii H
    Genes Cells; 1999 Jun; 4(6):363-73. PubMed ID: 10421845
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Functional cooperation of the interleukin-2 receptor beta chain and Jak1 in phosphatidylinositol 3-kinase recruitment and phosphorylation.
    Migone TS; Rodig S; Cacalano NA; Berg M; Schreiber RD; Leonard WJ
    Mol Cell Biol; 1998 Nov; 18(11):6416-22. PubMed ID: 9774657
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Activation of Stat5 by interleukin 2 requires a carboxyl-terminal region of the interleukin 2 receptor beta chain but is not essential for the proliferative signal transmission.
    Fujii H; Nakagawa Y; Schindler U; Kawahara A; Mori H; Gouilleux F; Groner B; Ihle JN; Minami Y; Miyazaki T
    Proc Natl Acad Sci U S A; 1995 Jun; 92(12):5482-6. PubMed ID: 7777534
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Different interleukin 2 receptor beta-chain tyrosines couple to at least two signaling pathways and synergistically mediate interleukin 2-induced proliferation.
    Friedmann MC; Migone TS; Russell SM; Leonard WJ
    Proc Natl Acad Sci U S A; 1996 Mar; 93(5):2077-82. PubMed ID: 8700888
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.