131 related articles for article (PubMed ID: 10517985)
1. Inter-individual differences in the metabolism of environmental toxicants: cytochrome P450 1A2 as a prototype.
Guengerich FP; Parikh A; Turesky RJ; Josephy PD
Mutat Res; 1999 Jul; 428(1-2):115-24. PubMed ID: 10517985
[TBL] [Abstract][Full Text] [Related]
2. Use of genetically engineered Salmonella typhimurium OY1002/1A2 strain coexpressing human cytochrome P450 1A2 and NADPH-cytochrome P450 reductase and bacterial O-acetyltransferase in SOS/umu assay.
Aryal P; Terashita T; Guengerich FP; Shimada T; Oda Y
Environ Mol Mutagen; 2000; 36(2):121-6. PubMed ID: 11013410
[TBL] [Abstract][Full Text] [Related]
3. Activation of heterocyclic aromatic amines by rat and human liver microsomes and by purified rat and human cytochrome P450 1A2.
Turesky RJ; Constable A; Richoz J; Varga N; Markovic J; Martin MV; Guengerich FP
Chem Res Toxicol; 1998 Aug; 11(8):925-36. PubMed ID: 9705755
[TBL] [Abstract][Full Text] [Related]
4. Regioselective differences in C(8)- and N-oxidation of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline by human and rat liver microsomes and cytochromes P450 1A2.
Turesky RJ; Parisod V; Huynh-Ba T; Langouët S; Guengerich FP
Chem Res Toxicol; 2001 Jul; 14(7):901-11. PubMed ID: 11453738
[TBL] [Abstract][Full Text] [Related]
5. Selection and characterization of human cytochrome P450 1A2 mutants with altered catalytic properties.
Parikh A; Josephy PD; Guengerich FP
Biochemistry; 1999 Apr; 38(17):5283-9. PubMed ID: 10220313
[TBL] [Abstract][Full Text] [Related]
6. Metabolic activation of heterocyclic amines and other procarcinogens in Salmonella typhimurium umu tester strains expressing human cytochrome P4501A1, 1A2, 1B1, 2C9, 2D6, 2E1, and 3A4 and human NADPH-P450 reductase and bacterial O-acetyltransferase.
Oda Y; Aryal P; Terashita T; Gillam EM; Guengerich FP; Shimada T
Mutat Res; 2001 May; 492(1-2):81-90. PubMed ID: 11377247
[TBL] [Abstract][Full Text] [Related]
7. Mechanisms of cytochrome P450 1A2-mediated formation of N-hydroxy arylamines and heterocyclic amines and their reaction with guanyl residues.
Guengerich FP; Humphreys WG; Yun CH; Hammons GJ; Kadlubar FF; Seto Y; Okazaki O; Martin MV
Princess Takamatsu Symp; 1995; 23():78-84. PubMed ID: 8844798
[TBL] [Abstract][Full Text] [Related]
8. Selection of human cytochrome P450 1A2 mutants with enhanced catalytic activity for heterocyclic amine N-hydroxylation.
Kim D; Guengerich FP
Biochemistry; 2004 Feb; 43(4):981-8. PubMed ID: 14744142
[TBL] [Abstract][Full Text] [Related]
9. Expression of recombinant human cytochrome P450 1A2 in Escherichia coli bacterial mutagenicity tester strain.
Chun YJ
Arch Pharm Res; 1998 Jun; 21(3):305-9. PubMed ID: 9875448
[TBL] [Abstract][Full Text] [Related]
10. Development of a new genotoxicity test system with Salmonella typhimurium OY1001/1A2 expressing human CYP1A2 and NADPH-P450 reductase.
Aryal P; Yoshikawa K; Terashita T; Guengerich FP; Shimada T; Oda Y
Mutat Res; 1999 Jun; 442(2):113-20. PubMed ID: 10393280
[TBL] [Abstract][Full Text] [Related]
11. Escherichia coli MTC, a human NADPH P450 reductase competent mutagenicity tester strain for the expression of human cytochrome P450 isoforms 1A1, 1A2, 2A6, 3A4, or 3A5: catalytic activities and mutagenicity studies.
Kranendonk M; Carreira F; Theisen P; Laires A; Fisher CW; Rueff J; Estabrook RW; Vermeulen NP
Mutat Res; 1999 Apr; 441(1):73-83. PubMed ID: 10224324
[TBL] [Abstract][Full Text] [Related]
12. Bioactivation of diesel exhaust particle extracts and their major nitrated polycyclic aromatic hydrocarbon components, 1-nitropyrene and dinitropyrenes, by human cytochromes P450 1A1, 1A2, and 1B1.
Yamazaki H; Hatanaka N; Kizu R; Hayakawa K; Shimada N; Guengerich FP; Nakajima M; Yokoi T
Mutat Res; 2000 Dec; 472(1-2):129-38. PubMed ID: 11113705
[TBL] [Abstract][Full Text] [Related]
13. Plasmid-mediated expression of the UmuDC mutagenesis proteins in an Escherichia coli strain engineered for human cytochrome P450 1A2-catalyzed activation of aromatic amines.
Josephy PD; Evans DH; Williamson V; Henry T; Guengerich FP
Mutat Res; 1999 Oct; 429(2):199-208. PubMed ID: 10526205
[TBL] [Abstract][Full Text] [Related]
14. Functional characterization of four allelic variants of human cytochrome P450 1A2.
Zhou H; Josephy PD; Kim D; Guengerich FP
Arch Biochem Biophys; 2004 Feb; 422(1):23-30. PubMed ID: 14725854
[TBL] [Abstract][Full Text] [Related]
15. Evaluation of Escherichia coli DJ4309 expressing human P450 1A2 in mutagenicity testing of complex food mixtures.
Constable A; Varga N; Josephy PD; Guy P; Turesky RJ
Mutat Res; 1999 Jun; 442(2):79-87. PubMed ID: 10393276
[TBL] [Abstract][Full Text] [Related]
16. Interspecies differences in metabolism of heterocyclic aromatic amines by rat and human P450 1A2.
Turesky RJ; Constable A; Fay LB; Guengerich FP
Cancer Lett; 1999 Sep; 143(2):109-12. PubMed ID: 10503887
[TBL] [Abstract][Full Text] [Related]
17. Metabolic activation of aromatic amine mutagens by simultaneous expression of human cytochrome P450 1A2, NADPH-cytochrome P450 reductase, and N-acetyltransferase in Escherichia coli.
Josephy PD; Evans DH; Parikh A; Guengerich FP
Chem Res Toxicol; 1998 Jan; 11(1):70-4. PubMed ID: 9477228
[TBL] [Abstract][Full Text] [Related]
18. Oxidations of p-alkoxyacylanilides catalyzed by human cytochrome P450 1A2: structure-activity relationships and simulation of rate constants of individual steps in catalysis.
Yun CH; Miller GP; Guengerich FP
Biochemistry; 2001 Apr; 40(14):4521-30. PubMed ID: 11284709
[TBL] [Abstract][Full Text] [Related]
19. 3-aminobenzanthrone, a human metabolite of the environmental pollutant 3-nitrobenzanthrone, forms DNA adducts after metabolic activation by human and rat liver microsomes: evidence for activation by cytochrome P450 1A1 and P450 1A2.
Arlt VM; Hewer A; Sorg BL; Schmeiser HH; Phillips DH; Stiborova M
Chem Res Toxicol; 2004 Aug; 17(8):1092-101. PubMed ID: 15310241
[TBL] [Abstract][Full Text] [Related]
20. The stimulatory role of human cytochrome b5 in the bioactivation activities of human CYP1A2, 2A6 and 2E1: a new cell expression system to study cytochrome P450 mediated biotransformation.
Duarte MP; Palma BB; Gilep AA; Laires A; Oliveira JS; Usanov SA; Rueff J; Kranendonk M
Mutagenesis; 2005 Mar; 20(2):93-100. PubMed ID: 15728263
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
