These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

189 related articles for article (PubMed ID: 10521480)

  • 1. The PEST domain of IkappaBalpha is necessary and sufficient for in vitro degradation by mu-calpain.
    Shumway SD; Maki M; Miyamoto S
    J Biol Chem; 1999 Oct; 274(43):30874-81. PubMed ID: 10521480
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Tumor necrosis factor-alpha-inducible IkappaBalpha proteolysis mediated by cytosolic m-calpain. A mechanism parallel to the ubiquitin-proteasome pathway for nuclear factor-kappab activation.
    Han Y; Weinman S; Boldogh I; Walker RK; Brasier AR
    J Biol Chem; 1999 Jan; 274(2):787-94. PubMed ID: 9873017
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Phosphorylation by the protein kinase CK2 promotes calpain-mediated degradation of IkappaBalpha.
    Shen J; Channavajhala P; Seldin DC; Sonenshein GE
    J Immunol; 2001 Nov; 167(9):4919-25. PubMed ID: 11673497
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Signal-dependent degradation of IkappaBalpha is mediated by an inducible destruction box that can be transferred to NF-kappaB, bcl-3 or p53.
    Wulczyn FG; Krappmann D; Scheidereit C
    Nucleic Acids Res; 1998 Apr; 26(7):1724-30. PubMed ID: 9512545
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Enhanced proteolysis of IkappaBalpha and IkappaBbeta proteins in astrocytes by Moloney murine leukemia virus (MoMuLV)-ts1 infection: a potential mechanism of NF-kappaB activation.
    Kim HT; Qiang W; Wong PK; Stoica G
    J Neurovirol; 2001 Oct; 7(5):466-75. PubMed ID: 11582519
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Constitutive phosphorylation of IkappaBalpha by casein kinase II occurs preferentially at serine 293: requirement for degradation of free IkappaBalpha.
    Schwarz EM; Van Antwerp D; Verma IM
    Mol Cell Biol; 1996 Jul; 16(7):3554-9. PubMed ID: 8668171
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Ubiquitin-dependent degradation of IkappaBalpha is mediated by a ubiquitin ligase Skp1/Cul 1/F-box protein FWD1.
    Hatakeyama S; Kitagawa M; Nakayama K; Shirane M; Matsumoto M; Hattori K; Higashi H; Nakano H; Okumura K; Onoé K; Good RA; Nakayama K
    Proc Natl Acad Sci U S A; 1999 Mar; 96(7):3859-63. PubMed ID: 10097128
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A mechanistic insight into a proteasome-independent constitutive inhibitor kappaBalpha (IkappaBalpha) degradation and nuclear factor kappaB (NF-kappaB) activation pathway in WEHI-231 B-cells.
    Shumway SD; Miyamoto S
    Biochem J; 2004 May; 380(Pt 1):173-80. PubMed ID: 14763901
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Signal-induced degradation of I(kappa)B(alpha): association with NF-kappaB and the PEST sequence in I(kappa)B(alpha) are not required.
    Van Antwerp DJ; Verma IM
    Mol Cell Biol; 1996 Nov; 16(11):6037-45. PubMed ID: 8887633
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Crucial role of the amino-terminal tyrosine residue 42 and the carboxyl-terminal PEST domain of I kappa B alpha in NF-kappa B activation by an oxidative stress.
    Schoonbroodt S; Ferreira V; Best-Belpomme M; Boelaert JR; Legrand-Poels S; Korner M; Piette J
    J Immunol; 2000 Apr; 164(8):4292-300. PubMed ID: 10754328
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Titanium particles stimulate COX-2 expression in synovial fibroblasts through an oxidative stress-induced, calpain-dependent, NF-kappaB pathway.
    Wei X; Zhang X; Flick LM; Drissi H; Schwarz EM; O'Keefe RJ
    Am J Physiol Cell Physiol; 2009 Aug; 297(2):C310-20. PubMed ID: 19494233
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Development of mKO2 fusion proteins for real-time imaging and mechanistic investigation of the degradation kinetics of human IκBα in living cells.
    Rahimova N; Babazada H; Higuchi Y; Yamashita F; Hashida M
    Biochim Biophys Acta Mol Cell Res; 2019 Feb; 1866(2):190-198. PubMed ID: 30391277
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Signal-dependent and -independent degradation of free and NF-kappa B-bound IkappaBalpha.
    Pando MP; Verma IM
    J Biol Chem; 2000 Jul; 275(28):21278-86. PubMed ID: 10801847
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The ankyrin repeats but not the PEST-like sequences are required for signal-dependent degradation of IkappaBalpha.
    Aoki T; Sano Y; Yamamoto T; Inoue JI
    Oncogene; 1996 Mar; 12(5):1159-64. PubMed ID: 8649809
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Pervanadate-induced nuclear factor-kappaB activation requires tyrosine phosphorylation and degradation of IkappaBalpha. Comparison with tumor necrosis factor-alpha.
    Mukhopadhyay A; Manna SK; Aggarwal BB
    J Biol Chem; 2000 Mar; 275(12):8549-55. PubMed ID: 10722693
    [TBL] [Abstract][Full Text] [Related]  

  • 16. SUMO-1 modification of IkappaBalpha inhibits NF-kappaB activation.
    Desterro JM; Rodriguez MS; Hay RT
    Mol Cell; 1998 Aug; 2(2):233-9. PubMed ID: 9734360
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Shared pathways of IkappaB kinase-induced SCF(betaTrCP)-mediated ubiquitination and degradation for the NF-kappaB precursor p105 and IkappaBalpha.
    Heissmeyer V; Krappmann D; Hatada EN; Scheidereit C
    Mol Cell Biol; 2001 Feb; 21(4):1024-35. PubMed ID: 11158290
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Site-specific tyrosine phosphorylation of IkappaBalpha negatively regulates its inducible phosphorylation and degradation.
    Singh S; Darnay BG; Aggarwal BB
    J Biol Chem; 1996 Dec; 271(49):31049-54. PubMed ID: 8940099
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mechanism of direct degradation of IkappaBalpha by 20S proteasome.
    Alvarez-Castelao B; Castaño JG
    FEBS Lett; 2005 Aug; 579(21):4797-802. PubMed ID: 16098527
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Glutamate activates NF-kappaB through calpain in neurons.
    Schölzke MN; Potrovita I; Subramaniam S; Prinz S; Schwaninger M
    Eur J Neurosci; 2003 Dec; 18(12):3305-10. PubMed ID: 14686903
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.