BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

135 related articles for article (PubMed ID: 10523799)

  • 21. Treatment with gefitinib or lapatinib induces drug resistance through downregulation of topoisomerase IIα expression.
    Bhosle J; Kiakos K; Porter AC; Wu J; Makris A; Hartley JA; Hochhauser D
    Mol Cancer Ther; 2013 Dec; 12(12):2897-908. PubMed ID: 24092808
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Reduced activity of topoisomerase II in an Adriamycin-resistant human stomach-adenocarcinoma cell line.
    Son YS; Suh JM; Ahn SH; Kim JC; Yi JY; Hur KC; Hong WS; Muller MT; Chung IK
    Cancer Chemother Pharmacol; 1998; 41(5):353-60. PubMed ID: 9523730
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Changes in subcellular distribution of topoisomerase IIalpha correlate with etoposide resistance in multicell spheroids and xenograft tumors.
    Oloumi A; MacPhail SH; Johnston PJ; Banáth JP; Olive PL
    Cancer Res; 2000 Oct; 60(20):5747-53. PubMed ID: 11059769
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Adenovirus-mediated human topoisomerase IIalpha gene transfer increases the sensitivity of etoposide-resistant human breast cancer cells.
    Zhou Z; Zwelling LA; Kawakami Y; An T; Kobayashi K; Herzog C; Kleinerman ES
    Cancer Res; 1999 Sep; 59(18):4618-24. PubMed ID: 10493516
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Evidence for a critical role of DNA topoisomerase IIalpha in drug sensitivity revealed by inducible antisense RNA in a human leukaemia cell line.
    Towatari M; Adachi K; Marunouchi T; Saito H
    Br J Haematol; 1998 Jun; 101(3):548-51. PubMed ID: 9633900
    [TBL] [Abstract][Full Text] [Related]  

  • 26. [Synergetic cytotoxicity of cisplatin and etoposide to leukemia cell line K562 and its mechanism].
    Ma WD; Yin MY; Jiang CW; Xu SR; Zhai LD; Zheng LF; Wang YL; Yan YL
    Ai Zheng; 2005 Aug; 24(8):958-64. PubMed ID: 16086873
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Reduction in drug-induced DNA double-strand breaks associated with beta1 integrin-mediated adhesion correlates with drug resistance in U937 cells.
    Hazlehurst LA; Valkov N; Wisner L; Storey JA; Boulware D; Sullivan DM; Dalton WS
    Blood; 2001 Sep; 98(6):1897-903. PubMed ID: 11535527
    [TBL] [Abstract][Full Text] [Related]  

  • 28. XPO1 Inhibition using Selinexor Synergizes with Chemotherapy in Acute Myeloid Leukemia by Targeting DNA Repair and Restoring Topoisomerase IIα to the Nucleus.
    Ranganathan P; Kashyap T; Yu X; Meng X; Lai TH; McNeil B; Bhatnagar B; Shacham S; Kauffman M; Dorrance AM; Blum W; Sampath D; Landesman Y; Garzon R
    Clin Cancer Res; 2016 Dec; 22(24):6142-6152. PubMed ID: 27358488
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Transfection of a human topoisomerase II alpha gene into etoposide-resistant human breast tumor cells sensitizes the cells to etoposide.
    Asano T; An T; Zwelling LA; Takano H; Fojo AT; Kleinerman ES
    Oncol Res; 1996; 8(3):101-10. PubMed ID: 8823806
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Topoisomerase II alpha gene expression in childhood acute lymphoblastic leukemia.
    Klumper E; Giaccone G; Pieters R; Broekema G; van Ark-Otte J; van Wering ER; Kaspers GJ; Veerman AJ
    Leukemia; 1995 Oct; 9(10):1653-60. PubMed ID: 7564505
    [TBL] [Abstract][Full Text] [Related]  

  • 31. The cytoplasmic trafficking of DNA topoisomerase IIalpha correlates with etoposide resistance in human myeloma cells.
    Engel R; Valkov NI; Gump JL; Hazlehurst L; Dalton WS; Sullivan DM
    Exp Cell Res; 2004 May; 295(2):421-31. PubMed ID: 15093741
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Mutations at arg486 and glu571 in human topoisomerase IIalpha confer resistance to amsacrine: relevance for antitumor drug resistance in human cells.
    Patel S; Keller BA; Fisher LM
    Mol Pharmacol; 2000 Apr; 57(4):784-91. PubMed ID: 10727526
    [TBL] [Abstract][Full Text] [Related]  

  • 33. The effect of 9-beta-D-arabinofuranosyl-2-fluoroadenine and 1-beta-D-arabinofuranosylcytosine on the cell cycle phase distribution, topoisomerase II level, mitoxantrone cytotoxicity, and DNA strand break production in K562 human leukemia cells.
    Loughlin S; Gandhi V; Plunkett W; Zwelling LA
    Cancer Chemother Pharmacol; 1996; 38(3):261-8. PubMed ID: 8646801
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Etoposide targets topoisomerase IIalpha and IIbeta in leukemic cells: isoform-specific cleavable complexes visualized and quantified in situ by a novel immunofluorescence technique.
    Willmore E; Frank AJ; Padget K; Tilby MJ; Austin CA
    Mol Pharmacol; 1998 Jul; 54(1):78-85. PubMed ID: 9658192
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Effects of wild-type p53 expression on the quantity and activity of topoisomerase IIalpha and beta in various human cancer cell lines.
    Hochhauser D; Valkov NI; Gump JL; Wei I; O'Hare C; Hartley J; Fan J; Bertino JR; Banerjee D; Sullivan DM
    J Cell Biochem; 1999 Nov; 75(2):245-57. PubMed ID: 10502297
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Immunohistochemical detection of DNA topoisomerase IIalpha, P-glycoprotein and multidrug resistance protein (MRP) in small-cell and non-small-cell lung cancer.
    Kreisholt J; Sorensen M; Jensen PB; Nielsen BS; Andersen CB; Sehested M
    Br J Cancer; 1998 May; 77(9):1469-73. PubMed ID: 9652763
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Alterations in the topoisomerase II alpha gene, messenger RNA, and subcellular protein distribution as well as reduced expression of the DNA topoisomerase II beta enzyme in a mitoxantrone-resistant HL-60 human leukemia cell line.
    Harker WG; Slade DL; Parr RL; Feldhoff PW; Sullivan DM; Holguin MH
    Cancer Res; 1995 Apr; 55(8):1707-16. PubMed ID: 7712479
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Interference with topoisomerase IIalpha potentiates melphalan cytotoxicity.
    Hirota H; Gosky D; Berger NA; Chatterjee S
    Int J Oncol; 2002 Feb; 20(2):311-8. PubMed ID: 11788894
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Drastic reduction of topoisomerase II alpha associated with major acquired resistance to topoisomerase II active agents but minor perturbations of cell growth.
    Hashimoto S; Chatterjee S; Ranjit GB; Bao C; Ford J; Ganapathi R; Berger SJ; Berger NA
    Oncol Res; 1995; 7(7-8):407-16. PubMed ID: 8747604
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Role of proteasomal degradation in the cell cycle-dependent regulation of DNA topoisomerase IIalpha expression.
    Salmena L; Lam V; McPherson JP; Goldenberg GJ
    Biochem Pharmacol; 2001 Apr; 61(7):795-802. PubMed ID: 11274964
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 7.