BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

131 related articles for article (PubMed ID: 10526205)

  • 1. Plasmid-mediated expression of the UmuDC mutagenesis proteins in an Escherichia coli strain engineered for human cytochrome P450 1A2-catalyzed activation of aromatic amines.
    Josephy PD; Evans DH; Williamson V; Henry T; Guengerich FP
    Mutat Res; 1999 Oct; 429(2):199-208. PubMed ID: 10526205
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Metabolic activation of aromatic amine mutagens by simultaneous expression of human cytochrome P450 1A2, NADPH-cytochrome P450 reductase, and N-acetyltransferase in Escherichia coli.
    Josephy PD; Evans DH; Parikh A; Guengerich FP
    Chem Res Toxicol; 1998 Jan; 11(1):70-4. PubMed ID: 9477228
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Evaluation of Escherichia coli DJ4309 expressing human P450 1A2 in mutagenicity testing of complex food mixtures.
    Constable A; Varga N; Josephy PD; Guy P; Turesky RJ
    Mutat Res; 1999 Jun; 442(2):79-87. PubMed ID: 10393276
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Use of genetically engineered Salmonella typhimurium OY1002/1A2 strain coexpressing human cytochrome P450 1A2 and NADPH-cytochrome P450 reductase and bacterial O-acetyltransferase in SOS/umu assay.
    Aryal P; Terashita T; Guengerich FP; Shimada T; Oda Y
    Environ Mol Mutagen; 2000; 36(2):121-6. PubMed ID: 11013410
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Biphasic effects of the flavonoids quercetin and naringenin on the metabolic activation of 2-amino-3,5-dimethylimidazo[4,5-f]quinoline by Salmonella typhimurium TA1538 co-expressing human cytochrome P450 1A2, NADPH-cytochrome P450 reductase, and cytochrome b5.
    Kang IH; Kim HJ; Oh H; Park YI; Dong MS
    Mutat Res; 2004 Jan; 545(1-2):37-47. PubMed ID: 14698415
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Activation of MeIQ (2-amino-3,4-dimethylimidazo- [4,5-f]quinoline) by sequence variants of recombinant human cytochrome P450 1A2.
    Josephy PD; Bibeau KL; Evans DH
    Environ Mol Mutagen; 2000; 35(4):328-35. PubMed ID: 10861951
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Development of a new genotoxicity test system with Salmonella typhimurium OY1001/1A2 expressing human CYP1A2 and NADPH-P450 reductase.
    Aryal P; Yoshikawa K; Terashita T; Guengerich FP; Shimada T; Oda Y
    Mutat Res; 1999 Jun; 442(2):113-20. PubMed ID: 10393280
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Expression of recombinant human cytochrome P450 1A2 in Escherichia coli bacterial mutagenicity tester strain.
    Chun YJ
    Arch Pharm Res; 1998 Jun; 21(3):305-9. PubMed ID: 9875448
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Recombinant human P450 forms 1A1, 1A2, and 1B1 catalyze the bioactivation of heterocyclic amine mutagens in Escherichia coli lacZ strains.
    Josephy PD; Batty SM; Boverhof DR
    Environ Mol Mutagen; 2001; 38(1):12-8. PubMed ID: 11473383
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Efficiency of MucAB and Escherichia coli UmuDC proteins in quinolone and UV mutagenesis in Salmonella typhimurium: effect of MucA and UmuD processing.
    Clerch B; Bravo JM; Llagostera M
    Mutat Res; 1996 Feb; 349(2):201-8. PubMed ID: 8600351
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Effects of the umuDC, mucAB, and samAB operons on the mutational specificity of chemical mutagenesis in Escherichia coli: I. Frameshift mutagenesis.
    Watanabe M; Nohmi T; Ohta T
    Mutat Res; 1994 Jan; 314(1):27-37. PubMed ID: 7504189
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Expression of human cytochrome P450 1A2 in Escherichia coli: a system for biotransformation and genotoxicity studies of chemical carcinogens.
    Kranendonk M; Mesquita P; Laires A; Vermeulen NP; Rueff J
    Mutagenesis; 1998 May; 13(3):263-9. PubMed ID: 9643585
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The stimulatory role of human cytochrome b5 in the bioactivation activities of human CYP1A2, 2A6 and 2E1: a new cell expression system to study cytochrome P450 mediated biotransformation.
    Duarte MP; Palma BB; Gilep AA; Laires A; Oliveira JS; Usanov SA; Rueff J; Kranendonk M
    Mutagenesis; 2005 Mar; 20(2):93-100. PubMed ID: 15728263
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The contribution of UDP-glucuronosyltransferase 1A9 on CYP1A2-mediated genotoxicity by aromatic and heterocyclic amines.
    Yueh MF; Nguyen N; Famourzadeh M; Strassburg CP; Oda Y; Guengerich FP; Tukey RH
    Carcinogenesis; 2001 Jun; 22(6):943-50. PubMed ID: 11375903
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mutability of Salmonella tester strains TA1538 (hisD3052) and TA1535 (hisG46) containing the UmuD' and UmuC proteins of Escherichia coli.
    Urios A; Herrera G; Aleixandre V; Sommer S; Blanco M
    Environ Mol Mutagen; 1994; 23(4):281-5. PubMed ID: 8013474
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Inter-individual differences in the metabolism of environmental toxicants: cytochrome P450 1A2 as a prototype.
    Guengerich FP; Parikh A; Turesky RJ; Josephy PD
    Mutat Res; 1999 Jul; 428(1-2):115-24. PubMed ID: 10517985
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Selection of human cytochrome P450 1A2 mutants with enhanced catalytic activity for heterocyclic amine N-hydroxylation.
    Kim D; Guengerich FP
    Biochemistry; 2004 Feb; 43(4):981-8. PubMed ID: 14744142
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Establishment of a Salmonella tester strain highly sensitive to mutagenic heterocyclic amines.
    Suzuki A; Kushida H; Iwata H; Watanabe M; Nohmi T; Fujita K; Gonzalez FJ; Kamataki T
    Cancer Res; 1998 May; 58(9):1833-8. PubMed ID: 9581821
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Specificity of replicative and SOS-inducible DNA polymerases in frameshift mutagenesis: mutability of Salmonella typhimurium strains overexpressing SOS-inducible DNA polymerases to 30 chemical mutagens.
    Matsui K; Yamada M; Imai M; Yamamoto K; Nohmi T
    DNA Repair (Amst); 2006 Apr; 5(4):465-78. PubMed ID: 16455311
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Bioactivation of diesel exhaust particle extracts and their major nitrated polycyclic aromatic hydrocarbon components, 1-nitropyrene and dinitropyrenes, by human cytochromes P450 1A1, 1A2, and 1B1.
    Yamazaki H; Hatanaka N; Kizu R; Hayakawa K; Shimada N; Guengerich FP; Nakajima M; Yokoi T
    Mutat Res; 2000 Dec; 472(1-2):129-38. PubMed ID: 11113705
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.