BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

141 related articles for article (PubMed ID: 10529249)

  • 1. Tandem heterocyclization activity of the multidomain 230 kDa HMWP2 subunit of Yersinia pestis yersiniabactin synthetase: interaction of the 1-1382 and 1383-2035 fragments.
    Suo Z; Walsh CT; Miller DA
    Biochemistry; 1999 Oct; 38(42):14023-35. PubMed ID: 10529249
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Yersiniabactin synthetase: probing the recognition of carrier protein domains by the catalytic heterocyclization domains, Cy1 and Cy2, in the chain-initiating HWMP2 subunit.
    Miller DA; Walsh CT
    Biochemistry; 2001 May; 40(17):5313-21. PubMed ID: 11318656
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Expression, purification, and characterization of HMWP2, a 229 kDa, six domain protein subunit of Yersiniabactin synthetase.
    Keating TA; Miller DA; Walsh CT
    Biochemistry; 2000 Apr; 39(16):4729-39. PubMed ID: 10769129
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The nonribosomal peptide synthetase HMWP2 forms a thiazoline ring during biogenesis of yersiniabactin, an iron-chelating virulence factor of Yersinia pestis.
    Gehring AM; Mori I; Perry RD; Walsh CT
    Biochemistry; 1998 Aug; 37(33):11637-50. PubMed ID: 9709002
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Thioesterase portability and peptidyl carrier protein swapping in yersiniabactin synthetase from Yersinia pestis.
    Suo Z
    Biochemistry; 2005 Mar; 44(12):4926-38. PubMed ID: 15779920
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Selectivity of the yersiniabactin synthetase adenylation domain in the two-step process of amino acid activation and transfer to a holo-carrier protein domain.
    Keating TA; Suo Z; Ehmann DE; Walsh CT
    Biochemistry; 2000 Mar; 39(9):2297-306. PubMed ID: 10694396
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Iron acquisition in plague: modular logic in enzymatic biogenesis of yersiniabactin by Yersinia pestis.
    Gehring AM; DeMoll E; Fetherston JD; Mori I; Mayhew GF; Blattner FR; Walsh CT; Perry RD
    Chem Biol; 1998 Oct; 5(10):573-86. PubMed ID: 9818149
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Purification, priming, and catalytic acylation of carrier protein domains in the polyketide synthase and nonribosomal peptidyl synthetase modules of the HMWP1 subunit of yersiniabactin synthetase.
    Suo Z; Tseng CC; Walsh CT
    Proc Natl Acad Sci U S A; 2001 Jan; 98(1):99-104. PubMed ID: 11134531
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Assembly of the Pseudomonas aeruginosa nonribosomal peptide siderophore pyochelin: In vitro reconstitution of aryl-4, 2-bisthiazoline synthetase activity from PchD, PchE, and PchF.
    Quadri LE; Keating TA; Patel HM; Walsh CT
    Biochemistry; 1999 Nov; 38(45):14941-54. PubMed ID: 10555976
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Site-specific observation of acyl intermediate processing in thiotemplate biosynthesis by fourier transform mass spectrometry: the polyketide module of yersiniabactin synthetase.
    Mazur MT; Walsh CT; Kelleher NL
    Biochemistry; 2003 Nov; 42(46):13393-400. PubMed ID: 14621984
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Yersiniabactin production requires the thioesterase domain of HMWP2 and YbtD, a putative phosphopantetheinylate transferase.
    Bobrov AG; Geoffroy VA; Perry RD
    Infect Immun; 2002 Aug; 70(8):4204-14. PubMed ID: 12117929
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Yersiniabactin synthetase: a four-protein assembly line producing the nonribosomal peptide/polyketide hybrid siderophore of Yersinia pestis.
    Miller DA; Luo L; Hillson N; Keating TA; Walsh CT
    Chem Biol; 2002 Mar; 9(3):333-44. PubMed ID: 11927258
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Kinetic and regiospecific interrogation of covalent intermediates in the nonribosomal peptide synthesis of yersiniabactin.
    McLoughlin SM; Kelleher NL
    J Am Chem Soc; 2004 Oct; 126(41):13265-75. PubMed ID: 15479080
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The yersiniabactin biosynthetic gene cluster of Yersinia enterocolitica: organization and siderophore-dependent regulation.
    Pelludat C; Rakin A; Jacobi CA; Schubert S; Heesemann J
    J Bacteriol; 1998 Feb; 180(3):538-46. PubMed ID: 9457855
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Monitoring multiple active sites on thiotemplate enzymes in parallel: a molecular movie of yersiniabactin bioassembly.
    McLoughlin SM; Kelleher NL
    J Am Chem Soc; 2005 Nov; 127(43):14984-5. PubMed ID: 16248611
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The EntF and EntE adenylation domains of Escherichia coli enterobactin synthetase: sequestration and selectivity in acyl-AMP transfers to thiolation domain cosubstrates.
    Ehmann DE; Shaw-Reid CA; Losey HC; Walsh CT
    Proc Natl Acad Sci U S A; 2000 Mar; 97(6):2509-14. PubMed ID: 10688898
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Acyl-CoA hydrolysis by the high molecular weight protein 1 subunit of yersiniabactin synthetase: mutational evidence for a cascade of four acyl-enzyme intermediates during hydrolytic editing.
    Suo Z; Chen H; Walsh CT
    Proc Natl Acad Sci U S A; 2000 Dec; 97(26):14188-93. PubMed ID: 11106385
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Epimerization of an L-cysteinyl to a D-cysteinyl residue during thiazoline ring formation in siderophore chain elongation by pyochelin synthetase from Pseudomonas aeruginosa.
    Patel HM; Tao J; Walsh CT
    Biochemistry; 2003 Sep; 42(35):10514-27. PubMed ID: 12950179
    [TBL] [Abstract][Full Text] [Related]  

  • 19. High-resolution structures of a siderophore-producing cyclization domain from Yersinia pestis offer a refined proposal of substrate binding.
    Gnann AD; Xia Y; Soule J; Barthélemy C; Mawani JS; Musoke SN; Castellano BM; Brignole EJ; Frueh DP; Dowling DP
    J Biol Chem; 2022 Oct; 298(10):102454. PubMed ID: 36063993
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Carrier protein recognition in siderophore-producing nonribosomal peptide synthetases.
    Marshall CG; Burkart MD; Meray RK; Walsh CT
    Biochemistry; 2002 Jul; 41(26):8429-37. PubMed ID: 12081492
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.