282 related articles for article (PubMed ID: 10530928)
1. Molecular modeling of the dopamine D2 and serotonin 5-HT1A receptor binding modes of the enantiomers of 5-OMe-BPAT.
Homan EJ; Wikström HV; Grol CJ
Bioorg Med Chem; 1999 Sep; 7(9):1805-20. PubMed ID: 10530928
[TBL] [Abstract][Full Text] [Related]
2. Synthesis and Pharmacology of the enantiomers of the potential atypical antipsychotic agents 5-OMe-BPAT and 5-OMe-(2,6-di-OMe)-BPAT.
Homan EJ; Copinga S; Unelius L; Jackson DM; Wikström HV; Grol CJ
Bioorg Med Chem; 1999 Jul; 7(7):1263-71. PubMed ID: 10465402
[TBL] [Abstract][Full Text] [Related]
3. Structural analogues of 5-OMe-BPAT: synthesis and interactions with dopamine D2, D3, and serotonin 5-HT1A receptors.
Homan EJ; Kroodsma E; Copinga S; Unelius L; Mohell N; Wikström HV; Grol CJ
Bioorg Med Chem; 1999 Jun; 7(6):1111-21. PubMed ID: 10428381
[TBL] [Abstract][Full Text] [Related]
4. C5-substituted derivatives of 5-OMe-BPAT: synthesis and interactions with dopamine D2 and serotonin 5-HT1A receptors.
Homan EJ; Tulp MT; Nilsson JE; Wikström HV; Grol CJ
Bioorg Med Chem; 1999 Nov; 7(11):2541-8. PubMed ID: 10632064
[TBL] [Abstract][Full Text] [Related]
5. 2-aminotetralin-derived substituted benzamides with mixed dopamine D2, D3, and serotonin 5-HT1A receptor binding properties: a novel class of potential atypical antipsychotic agents.
Homan EJ; Copinga S; Elfström L; van der Veen T; Hallema JP; Mohell N; Unelius L; Johansson R; Wikström HV; Grol CJ
Bioorg Med Chem; 1998 Nov; 6(11):2111-26. PubMed ID: 9881101
[TBL] [Abstract][Full Text] [Related]
6. 5-HT1A-versus D2-receptor selectivity of flesinoxan and analogous N4-substituted N1-arylpiperazines.
Kuipers W; Kruse CG; van Wijngaarden I; Standaar PJ; Tulp MT; Veldman N; Spek AL; IJzerman AP
J Med Chem; 1997 Jan; 40(3):300-12. PubMed ID: 9022796
[TBL] [Abstract][Full Text] [Related]
7. Differential serotoninergic and dopaminergic activities of the (R)- and the (S)-enantiomers of 2-(di-n-propylamino)tetralin.
Yu H; Liu Y; Malmberg A; Mohell N; Hacksell U; Lewander T
Eur J Pharmacol; 1996 May; 303(3):151-62. PubMed ID: 8813561
[TBL] [Abstract][Full Text] [Related]
8. Molecular basis for the binding of 2-aminotetralins to human dopamine D2A and D3 receptors.
Malmberg A; Nordvall G; Johansson AM; Mohell N; Hacksell U
Mol Pharmacol; 1994 Aug; 46(2):299-312. PubMed ID: 8078492
[TBL] [Abstract][Full Text] [Related]
9. Novel computational model for the interaction of dopamine with the D2 receptor.
Moereels H; Leysen JE
Recept Channels; 1993; 1(2):89-97. PubMed ID: 8081722
[TBL] [Abstract][Full Text] [Related]
10. Comparison of 5-HT1A and dopamine D2 pharmacophores. X-ray structures and affinities of conformationally constrained ligands.
Chidester CG; Lin CH; Lahti RA; Haadsma-Svensson SR; Smith MW
J Med Chem; 1993 May; 36(10):1301-15. PubMed ID: 8496900
[TBL] [Abstract][Full Text] [Related]
11. 1-aryl-4-[(5-methoxy-1,2,3, 4-tetrahydronaphthalen-1-yl)alkyl]piperazines and their analogues: influence of the stereochemistry of the tetrahydronaphthalen-1-yl nucleus on 5-HT1A receptor affinity and selectivity versus alpha1 and D2 receptors. 5.
Perrone R; Berardi F; Colabufo NA; Leopoldo M; Tortorella V
J Med Chem; 1999 Feb; 42(3):490-6. PubMed ID: 9986719
[TBL] [Abstract][Full Text] [Related]
12. Synthesis of novel 5-substituted 3-amino-3,4-dihydro-2H-1-benzopyran derivatives and their interactions with the 5-HT1A receptor.
Hammarberg E; Nordvall G; Leideborg R; Nylöf M; Hanson S; Johansson L; Thorberg SO; Tolf BR; Jerning E; Svantesson GT; Mohell N; Ahlgren C; Westlind-Danielsson A; Csöregh I; Johansson R
J Med Chem; 2000 Jul; 43(15):2837-50. PubMed ID: 10956192
[TBL] [Abstract][Full Text] [Related]
13. Site-directed mutagenesis of the human dopamine D2 receptor.
Mansour A; Meng F; Meador-Woodruff JH; Taylor LP; Civelli O; Akil H
Eur J Pharmacol; 1992 Oct; 227(2):205-14. PubMed ID: 1358663
[TBL] [Abstract][Full Text] [Related]
14. Generalization of serotonin (5-HT)1A agonists and the antipsychotics, clozapine, ziprasidone and S16924, but not haloperidol, to the discriminative stimuli elicited by PD128,907 and 7-OH-DPAT.
Dekeyne A; Rivet JM; Gobert A; Millan MJ
Neuropharmacology; 2001 Jun; 40(7):899-910. PubMed ID: 11378160
[TBL] [Abstract][Full Text] [Related]
15. N4-unsubstituted N1-arylpiperazines as high-affinity 5-HT1A receptor ligands.
Kuipers W; van Wijngaarden I; Kruse CG; ter Horst-van Amstel M; Tulp MT; IJzerman AP
J Med Chem; 1995 May; 38(11):1942-54. PubMed ID: 7783126
[TBL] [Abstract][Full Text] [Related]
16. Characterization of the 5-HT(7) receptor. Determination of the pharmacophore for 5-HT(7) receptor agonism and CoMFA-based modeling of the agonist binding site.
Vermeulen ES; Schmidt AW; Sprouse JS; Wikström HV; Grol CJ
J Med Chem; 2003 Dec; 46(25):5365-74. PubMed ID: 14640545
[TBL] [Abstract][Full Text] [Related]
17. Pharmacodynamic and pharmacokinetic studies in rats of S-8-(2-Furyl)- and R-8-phenyl-2-(di-n-propylamino) tetralin, two novel 5-HT1A receptor agonists in-vitro with different properties in-vivo.
Yu H; Liu Y; Li HB; Martin AR; Hacksell U; Lewander T
J Pharm Pharmacol; 1997 Feb; 49(2):169-77. PubMed ID: 9055190
[TBL] [Abstract][Full Text] [Related]
18. Interactions of ligands with active and inactive conformations of the dopamine D2 receptor.
Malmberg A; Mohell N; Backlund Höök B; Johansson AM; Hacksell U; Nordvall G
Eur J Pharmacol; 1998 Apr; 346(2-3):299-307. PubMed ID: 9652373
[TBL] [Abstract][Full Text] [Related]
19. Investigation of D₁ receptor-agonist interactions and D₁/D₂ agonist selectivity using a combination of pharmacophore and receptor homology modeling.
Malo M; Brive L; Luthman K; Svensson P
ChemMedChem; 2012 Mar; 7(3):483-94, 338. PubMed ID: 22315216
[TBL] [Abstract][Full Text] [Related]
20. Centrally acting serotonergic and dopaminergic agents. 2. Synthesis and structure-activity relationships of 2,3,3a,4,9,9a-hexahydro-1H-benz[f]indole derivatives.
Lin CH; Haadsma-Svensson SR; Phillips G; Lahti RA; McCall RB; Piercey MF; Schreur PJ; Von Voigtlander PF; Smith MW; Chidester CG
J Med Chem; 1993 Apr; 36(8):1069-83. PubMed ID: 8097538
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
