182 related articles for article (PubMed ID: 10531314)
1. Conversion of aspartate aminotransferase into an L-aspartate beta-decarboxylase by a triple active-site mutation.
Graber R; Kasper P; Malashkevich VN; Strop P; Gehring H; Jansonius JN; Christen P
J Biol Chem; 1999 Oct; 274(44):31203-8. PubMed ID: 10531314
[TBL] [Abstract][Full Text] [Related]
2. Structure and mechanism of a cysteine sulfinate desulfinase engineered on the aspartate aminotransferase scaffold.
Fernandez FJ; de Vries D; Peña-Soler E; Coll M; Christen P; Gehring H; Vega MC
Biochim Biophys Acta; 2012 Feb; 1824(2):339-49. PubMed ID: 22138634
[TBL] [Abstract][Full Text] [Related]
3. Changing the reaction specificity of a pyridoxal-5'-phosphate-dependent enzyme.
Graber R; Kasper P; Malashkevich VN; Sandmeier E; Berger P; Gehring H; Jansonius JN; Christen P
Eur J Biochem; 1995 Sep; 232(2):686-90. PubMed ID: 7556224
[TBL] [Abstract][Full Text] [Related]
4. Active-site Arg --> Lys substitutions alter reaction and substrate specificity of aspartate aminotransferase.
Vacca RA; Giannattasio S; Graber R; Sandmeier E; Marra E; Christen P
J Biol Chem; 1997 Aug; 272(35):21932-7. PubMed ID: 9268327
[TBL] [Abstract][Full Text] [Related]
5. Tyr225 in aspartate aminotransferase: contribution of the hydrogen bond between Tyr225 and coenzyme to the catalytic reaction.
Inoue K; Kuramitsu S; Okamoto A; Hirotsu K; Higuchi T; Morino Y; Kagamiyama H
J Biochem; 1991 Apr; 109(4):570-6. PubMed ID: 1869510
[TBL] [Abstract][Full Text] [Related]
6. Substitution of apolar residues in the active site of aspartate aminotransferase by histidine. Effects on reaction and substrate specificity.
Vacca RA; Christen P; Malashkevich VN; Jansonius JN; Sandmeier E
Eur J Biochem; 1995 Jan; 227(1-2):481-7. PubMed ID: 7851426
[TBL] [Abstract][Full Text] [Related]
7. Conversion of tyrosine phenol-lyase to dicarboxylic amino acid beta-lyase, an enzyme not found in nature.
Mouratou B; Kasper P; Gehring H; Christen P
J Biol Chem; 1999 Jan; 274(3):1320-5. PubMed ID: 9880502
[TBL] [Abstract][Full Text] [Related]
8. Enhanced transaminase activity of a bifunctional L-aspartate 4-decarboxylase.
Wang NC; Lee CY
Biochem Biophys Res Commun; 2007 May; 356(2):368-73. PubMed ID: 17353007
[TBL] [Abstract][Full Text] [Related]
9. Reaction of aspartate aminotransferase with L-erythro-3-hydroxyaspartate: involvement of Tyr70 in stabilization of the catalytic intermediates.
Hayashi H; Kagamiyama H
Biochemistry; 1995 Jul; 34(29):9413-23. PubMed ID: 7626611
[TBL] [Abstract][Full Text] [Related]
10. Role of Asp222 in the catalytic mechanism of Escherichia coli aspartate aminotransferase: the amino acid residue which enhances the function of the enzyme-bound coenzyme pyridoxal 5'-phosphate.
Yano T; Kuramitsu S; Tanase S; Morino Y; Kagamiyama H
Biochemistry; 1992 Jun; 31(25):5878-87. PubMed ID: 1610831
[TBL] [Abstract][Full Text] [Related]
11. The structural basis for the altered substrate specificity of the R292D active site mutant of aspartate aminotransferase from E. coli.
Almo SC; Smith DL; Danishefsky AT; Ringe D
Protein Eng; 1994 Mar; 7(3):405-12. PubMed ID: 7909946
[TBL] [Abstract][Full Text] [Related]
12. The aspartate aminotransferase-catalysed exchange of the alpha-protons of aspartate and glutamate: the effects of the R386A and R292V mutations on this exchange reaction.
Mahon MM; Graber R; Christen P; Malthouse JP
Biochim Biophys Acta; 1999 Sep; 1434(1):191-201. PubMed ID: 10556573
[TBL] [Abstract][Full Text] [Related]
13. Structural and mechanistic analysis of two refined crystal structures of the pyridoxal phosphate-dependent enzyme dialkylglycine decarboxylase.
Toney MD; Hohenester E; Keller JW; Jansonius JN
J Mol Biol; 1995 Jan; 245(2):151-79. PubMed ID: 7799433
[TBL] [Abstract][Full Text] [Related]
14. Noncoded amino acid replacement probes of the aspartate aminotransferase mechanism.
Park Y; Luo J; Schultz PG; Kirsch JF
Biochemistry; 1997 Aug; 36(34):10517-25. PubMed ID: 9265632
[TBL] [Abstract][Full Text] [Related]
15. Substrate inactivation of bacterial L-aspartate α-decarboxylase from Corynebacterium jeikeium K411 and improvement of molecular stability by saturation mutagenesis.
Mo Q; Mao A; Li Y; Shi G
World J Microbiol Biotechnol; 2019 Mar; 35(4):62. PubMed ID: 30923994
[TBL] [Abstract][Full Text] [Related]
16. Directed evolution relieves product inhibition and confers in vivo function to a rationally designed tyrosine aminotransferase.
Rothman SC; Voorhies M; Kirsch JF
Protein Sci; 2004 Mar; 13(3):763-72. PubMed ID: 14767072
[TBL] [Abstract][Full Text] [Related]
17. The role of residues outside the active site: structural basis for function of C191 mutants of Escherichia coli aspartate aminotransferase.
Jeffery CJ; Gloss LM; Petsko GA; Ringe D
Protein Eng; 2000 Feb; 13(2):105-12. PubMed ID: 10708649
[TBL] [Abstract][Full Text] [Related]
18. Evolution of enzymatic activities in the orotidine 5'-monophosphate decarboxylase suprafamily: enhancing the promiscuous D-arabino-hex-3-ulose 6-phosphate synthase reaction catalyzed by 3-keto-L-gulonate 6-phosphate decarboxylase.
Yew WS; Akana J; Wise EL; Rayment I; Gerlt JA
Biochemistry; 2005 Feb; 44(6):1807-15. PubMed ID: 15697206
[TBL] [Abstract][Full Text] [Related]
19. Structures of Escherichia coli histidinol-phosphate aminotransferase and its complexes with histidinol-phosphate and N-(5'-phosphopyridoxyl)-L-glutamate: double substrate recognition of the enzyme.
Haruyama K; Nakai T; Miyahara I; Hirotsu K; Mizuguchi H; Hayashi H; Kagamiyama H
Biochemistry; 2001 Apr; 40(15):4633-44. PubMed ID: 11294630
[TBL] [Abstract][Full Text] [Related]
20. Inactive S298R disassembles the dodecameric L-aspartate 4-decarboxylase into dimers.
Wang NC; Ko TP; Lee CY
Biochem Biophys Res Commun; 2008 Sep; 374(1):134-7. PubMed ID: 18602363
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]