BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

334 related articles for article (PubMed ID: 10534317)

  • 21. Identification of the major human hepatic cytochrome P450 involved in activation and N-dechloroethylation of ifosfamide.
    Walker D; Flinois JP; Monkman SC; Beloc C; Boddy AV; Cholerton S; Daly AK; Lind MJ; Pearson AD; Beaune PH
    Biochem Pharmacol; 1994 Mar; 47(7):1157-63. PubMed ID: 8161344
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Oxidative metabolism of clarithromycin in the presence of human liver microsomes. Major role for the cytochrome P4503A (CYP3A) subfamily.
    Rodrigues AD; Roberts EM; Mulford DJ; Yao Y; Ouellet D
    Drug Metab Dispos; 1997 May; 25(5):623-30. PubMed ID: 9152603
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Species differences in stereoselective metabolism of mephenytoin by cytochrome P450 (CYP2C and CYP3A).
    Yasumori T; Chen L; Nagata K; Yamazoe Y; Kato R
    J Pharmacol Exp Ther; 1993 Jan; 264(1):89-94. PubMed ID: 8423554
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Metabolism of endosulfan-alpha by human liver microsomes and its utility as a simultaneous in vitro probe for CYP2B6 and CYP3A4.
    Casabar RC; Wallace AD; Hodgson E; Rose RL
    Drug Metab Dispos; 2006 Oct; 34(10):1779-85. PubMed ID: 16855053
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Stereoselective metabolism of endosulfan by human liver microsomes and human cytochrome P450 isoforms.
    Lee HK; Moon JK; Chang CH; Choi H; Park HW; Park BS; Lee HS; Hwang EC; Lee YD; Liu KH; Kim JH
    Drug Metab Dispos; 2006 Jul; 34(7):1090-5. PubMed ID: 16581944
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Halofantrine metabolism in microsomes in man: major role of CYP 3A4 and CYP 3A5.
    Baune B; Flinois JP; Furlan V; Gimenez F; Taburet AM; Becquemont L; Farinotti R
    J Pharm Pharmacol; 1999 Apr; 51(4):419-26. PubMed ID: 10385214
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Species difference in stereoselective involvement of CYP3A in the mono-N-dealkylation of disopyramide.
    Zhang L; Fitzloff JF; Engel LC; Cook CS
    Xenobiotica; 2001 Feb; 31(2):73-83. PubMed ID: 11407536
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Hydroxylation and N-dechloroethylation of Ifosfamide and deuterated Ifosfamide by the human cytochrome p450s and their commonly occurring polymorphisms.
    Calinski DM; Zhang H; Ludeman S; Dolan ME; Hollenberg PF
    Drug Metab Dispos; 2015 Jul; 43(7):1084-90. PubMed ID: 25934575
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Comparative studies of in vitro inhibition of cytochrome P450 3A4-dependent testosterone 6beta-hydroxylation by roxithromycin and its metabolites, troleandomycin, and erythromycin.
    Yamazaki H; Shimada T
    Drug Metab Dispos; 1998 Nov; 26(11):1053-7. PubMed ID: 9806945
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Cytochrome P-450 2B6 is responsible for interindividual variability of propofol hydroxylation by human liver microsomes.
    Court MH; Duan SX; Hesse LM; Venkatakrishnan K; Greenblatt DJ
    Anesthesiology; 2001 Jan; 94(1):110-9. PubMed ID: 11135730
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Identification of CYP3A4 as the enzyme involved in the mono-N-dealkylation of disopyramide enantiomers in humans.
    Echizen H; Tanizaki M; Tatsuno J; Chiba K; Berwick T; Tani M; Gonzalez FJ; Ishizaki T
    Drug Metab Dispos; 2000 Aug; 28(8):937-44. PubMed ID: 10901704
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Role of CYP3A4 and CYP2C19 in the stereoselective metabolism of lansoprazole by human liver microsomes.
    Katsuki H; Hamada A; Nakamura C; Arimori K; Nakano M
    Eur J Clin Pharmacol; 2001 Dec; 57(10):709-15. PubMed ID: 11829200
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Stereoselective metabolism of cisapride and enantiomer-enantiomer interaction in human cytochrome P450 enzymes: major role of CYP3A.
    Desta Z; Soukhova N; Morocho AM; Flockhart DA
    J Pharmacol Exp Ther; 2001 Aug; 298(2):508-20. PubMed ID: 11454912
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Metabolism of levo-alpha-Acetylmethadol (LAAM) by human liver cytochrome P450: involvement of CYP3A4 characterized by atypical kinetics with two binding sites.
    Oda Y; Kharasch ED
    J Pharmacol Exp Ther; 2001 Apr; 297(1):410-22. PubMed ID: 11259570
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Involvement of CYP2B6 in n-demethylation of ketamine in human liver microsomes.
    Yanagihara Y; Kariya S; Ohtani M; Uchino K; Aoyama T; Yamamura Y; Iga T
    Drug Metab Dispos; 2001 Jun; 29(6):887-90. PubMed ID: 11353758
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Biotransformation of parathion in human liver: participation of CYP3A4 and its inactivation during microsomal parathion oxidation.
    Butler AM; Murray M
    J Pharmacol Exp Ther; 1997 Feb; 280(2):966-73. PubMed ID: 9023313
    [TBL] [Abstract][Full Text] [Related]  

  • 37. CYP3A4, CYP2C9 and CYP2B6 expression and ifosfamide turnover in breast cancer tissue microsomes.
    Schmidt R; Baumann F; Knüpfer H; Brauckhoff M; Horn LC; Schönfelder M; Köhler U; Preiss R
    Br J Cancer; 2004 Feb; 90(4):911-6. PubMed ID: 14970873
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Human reductive halothane metabolism in vitro is catalyzed by cytochrome P450 2A6 and 3A4.
    Spracklin DK; Thummel KE; Kharasch ED
    Drug Metab Dispos; 1996 Sep; 24(9):976-83. PubMed ID: 8886607
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Troglitazone quinone formation catalyzed by human and rat CYP3A: an atypical CYP oxidation reaction.
    He K; Woolf TF; Kindt EK; Fielder AE; Talaat RE
    Biochem Pharmacol; 2001 Jul; 62(2):191-8. PubMed ID: 11389877
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Interactions of two major metabolites of prasugrel, a thienopyridine antiplatelet agent, with the cytochromes P450.
    Rehmel JL; Eckstein JA; Farid NA; Heim JB; Kasper SC; Kurihara A; Wrighton SA; Ring BJ
    Drug Metab Dispos; 2006 Apr; 34(4):600-7. PubMed ID: 16415119
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 17.