185 related articles for article (PubMed ID: 10534320)
1. Metabolites of [(14)C]-5-(2-ethyl-2H-tetrazol-5-yl)-1-methyl-1,2,3, 6-tetrahydropyridine in mice, rats, dogs, and humans.
Christensen EB; Andersen JB; Pedersen H; Jensen KG; Dalgaard L
Drug Metab Dispos; 1999 Nov; 27(11):1341-9. PubMed ID: 10534320
[TBL] [Abstract][Full Text] [Related]
2. In vitro metabolism of the M1-muscarinic agonist 5-(2-ethyl-2H-tetrazol-5-yl)-1-methyl-1,2,3,6-tetrahydropyridine by human hepatic cytochromes P-450 determined at pH 7.4 and 8.5.
Jensen KG; Dalgaard L
Drug Metab Dispos; 1999 Jan; 27(1):125-32. PubMed ID: 9884321
[TBL] [Abstract][Full Text] [Related]
3. Preclinical pharmacokinetics and metabolism of 6-(4-(2,5-difluorophenyl)oxazol-5-yl)-3-isopropyl-[1,2,4]-triazolo[4,3-a]pyridine, a novel and selective p38alpha inhibitor: identification of an active metabolite in preclinical species and human liver microsomes.
Kalgutkar AS; Hatch HL; Kosea F; Nguyen HT; Choo EF; McClure KF; Taylor TJ; Henne KR; Kuperman AV; Dombroski MA; Letavic MA
Biopharm Drug Dispos; 2006 Nov; 27(8):371-86. PubMed ID: 16944451
[TBL] [Abstract][Full Text] [Related]
4. Comparative metabolism of 14C-labeled apixaban in mice, rats, rabbits, dogs, and humans.
Zhang D; He K; Raghavan N; Wang L; Mitroka J; Maxwell BD; Knabb RM; Frost C; Schuster A; Hao F; Gu Z; Humphreys WG; Grossman SJ
Drug Metab Dispos; 2009 Aug; 37(8):1738-48. PubMed ID: 19420130
[TBL] [Abstract][Full Text] [Related]
5. In vitro and in vivo metabolism of desogestrel in several species.
Verhoeven CH; Krebbers SF; Wagenaars GN; Vos RM
Drug Metab Dispos; 1998 Sep; 26(9):927-36. PubMed ID: 9733673
[TBL] [Abstract][Full Text] [Related]
6. NTP technical report on the toxicity and metabolism studies of chloral hydrate (CAS No. 302-17-0). Administered by gavage to F344/N rats and B6C3F1 mice.
Beland FA
Toxic Rep Ser; 1999 Aug; (59):1-66, A1-E7. PubMed ID: 11803702
[TBL] [Abstract][Full Text] [Related]
7. Metabolism, excretion, and pharmacokinetics of (3-{[4-tert-butyl-benzyl)-(pyridine-3-sulfonyl)-amino]-methyl}-phenoxy)-acetic acid, an EP2 receptor-selective prostaglandin E2 agonist, in male and female Sprague-Dawley rats.
Johnson KA; Prakash C
Drug Metab Dispos; 2005 Aug; 33(8):1191-201. PubMed ID: 15886349
[TBL] [Abstract][Full Text] [Related]
8. Biotransformation of tolterodine, a new muscarinic receptor antagonist, in mice, rats, and dogs.
Andersson SH; Lindgren A; Postlind H
Drug Metab Dispos; 1998 Jun; 26(6):528-35. PubMed ID: 9616187
[TBL] [Abstract][Full Text] [Related]
9. Comparative metabolism of radiolabeled muraglitazar in animals and humans by quantitative and qualitative metabolite profiling.
Zhang D; Wang L; Raghavan N; Zhang H; Li W; Cheng PT; Yao M; Zhang L; Zhu M; Bonacorsi S; Yeola S; Mitroka J; Hariharan N; Hosagrahara V; Chandrasena G; Shyu WC; Humphreys WG
Drug Metab Dispos; 2007 Jan; 35(1):150-67. PubMed ID: 17062777
[TBL] [Abstract][Full Text] [Related]
10. HPLC-NMR with severe column overloading: fast-track metabolite identification in urine and bile samples from rat and dog treated with [14C]-ZD6126.
Lenz EM; D'Souza RA; Jordan AC; King CD; Smith SM; Phillips PJ; McCormick AD; Roberts DW
J Pharm Biomed Anal; 2007 Feb; 43(3):1065-77. PubMed ID: 17030109
[TBL] [Abstract][Full Text] [Related]
11. Biotransformation of 6-methoxy-3-(3',4',5'-trimethoxy-benzoyl)-1H-indole (BPR0L075), a novel antimicrotubule agent, by mouse, rat, dog, and human liver microsomes.
Yao HT; Wu YS; Chang YW; Hsieh HP; Chen WC; Lan SJ; Chen CT; Chao YS; Chang L; Sun HY; Yeh TK
Drug Metab Dispos; 2007 Jul; 35(7):1042-9. PubMed ID: 17403915
[TBL] [Abstract][Full Text] [Related]
12. Studies on the metabolism of the novel, selective cyclooxygenase-2 inhibitor indomethacin phenethylamide in rat, mouse, and human liver microsomes: identification of active metabolites.
Remmel RP; Crews BC; Kozak KR; Kalgutkar AS; Marnett LJ
Drug Metab Dispos; 2004 Jan; 32(1):113-22. PubMed ID: 14709628
[TBL] [Abstract][Full Text] [Related]
13. Evaluation of blood-brain barrier passage of a muscarine M1 agonist and a series of analogous tetrahydropyridines measured by in vivo microdialysis.
Sveigaard HH; Dalgaard L
Pharm Res; 2000 Jan; 17(1):70-6. PubMed ID: 10714611
[TBL] [Abstract][Full Text] [Related]
14. Comparative theobromine metabolism in five mammalian species.
Miller GE; Radulovic LL; DeWit RH; Brabec MJ; Tarka SM; Cornish HH
Drug Metab Dispos; 1984; 12(2):154-60. PubMed ID: 6144479
[TBL] [Abstract][Full Text] [Related]
15. CYP2C8- and CYP3A-mediated C-demethylation of (3-{[(4-tert-butylbenzyl)-(pyridine-3-sulfonyl)-amino]-methyl}-phenoxy)-acetic acid (CP-533,536), an EP2 receptor-selective prostaglandin E2 agonist: characterization of metabolites by high-resolution liquid chromatography-tandem mass spectrometry and liquid chromatography/mass spectrometry-nuclear magnetic resonance.
Prakash C; Wang W; O'Connell T; Johnson KA
Drug Metab Dispos; 2008 Oct; 36(10):2093-103. PubMed ID: 18653741
[TBL] [Abstract][Full Text] [Related]
16. Biotransformation of the novel inotropic agent toborinone (OPC-18790) in rats and dogs. Evidence for the formation of novel glutathione and two cysteine conjugates.
Kitani M; Miyamoto G; Nagasawa M; Yamada T; Matsubara J; Uchida M; Odomi M
Drug Metab Dispos; 1997 Jun; 25(6):663-74. PubMed ID: 9193867
[TBL] [Abstract][Full Text] [Related]
17. Biotransformation of carbon-14-labeled muraglitazar in male mice: interspecies difference in metabolic pathways leading to unique metabolites.
Li W; Zhang D; Wang L; Zhang H; Cheng PT; Zhang D; Everett DW; Humphreys WG
Drug Metab Dispos; 2006 May; 34(5):807-20. PubMed ID: 16467134
[TBL] [Abstract][Full Text] [Related]
18. Metabolism and excretion of the novel bioreductive prodrug PR-104 in mice, rats, dogs, and humans.
Gu Y; Atwell GJ; Wilson WR
Drug Metab Dispos; 2010 Mar; 38(3):498-508. PubMed ID: 20019245
[TBL] [Abstract][Full Text] [Related]
19. Metabolism, distribution and excretion of a selective N-methyl-D-aspartate receptor antagonist, traxoprodil, in rats and dogs.
Prakash C; Cui D; Potchoiba MJ; Butler T
Drug Metab Dispos; 2007 Aug; 35(8):1350-64. PubMed ID: 17496205
[TBL] [Abstract][Full Text] [Related]
20. Biotransformation of cerivastatin in mice, rats, and dogs in vivo.
Boberg M; Angerbauer R; Kanhai WK; Karl W; Kern A; Radtke M; Steinke W
Drug Metab Dispos; 1998 Jul; 26(7):640-52. PubMed ID: 9660846
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
