BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

248 related articles for article (PubMed ID: 10535941)

  • 1. SnoN and Ski protooncoproteins are rapidly degraded in response to transforming growth factor beta signaling.
    Sun Y; Liu X; Ng-Eaton E; Lodish HF; Weinberg RA
    Proc Natl Acad Sci U S A; 1999 Oct; 96(22):12442-7. PubMed ID: 10535941
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Smad3 recruits the anaphase-promoting complex for ubiquitination and degradation of SnoN.
    Stroschein SL; Bonni S; Wrana JL; Luo K
    Genes Dev; 2001 Nov; 15(21):2822-36. PubMed ID: 11691834
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Interaction of the Ski oncoprotein with Smad3 regulates TGF-beta signaling.
    Sun Y; Liu X; Eaton EN; Lane WS; Lodish HF; Weinberg RA
    Mol Cell; 1999 Oct; 4(4):499-509. PubMed ID: 10549282
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Two short segments of Smad3 are important for specific interaction of Smad3 with c-Ski and SnoN.
    Mizuide M; Hara T; Furuya T; Takeda M; Kusanagi K; Inada Y; Mori M; Imamura T; Miyazawa K; Miyazono K
    J Biol Chem; 2003 Jan; 278(1):531-6. PubMed ID: 12426322
    [TBL] [Abstract][Full Text] [Related]  

  • 5. NEDD4-2 (neural precursor cell expressed, developmentally down-regulated 4-2) negatively regulates TGF-beta (transforming growth factor-beta) signalling by inducing ubiquitin-mediated degradation of Smad2 and TGF-beta type I receptor.
    Kuratomi G; Komuro A; Goto K; Shinozaki M; Miyazawa K; Miyazono K; Imamura T
    Biochem J; 2005 Mar; 386(Pt 3):461-70. PubMed ID: 15496141
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The transforming activity of Ski and SnoN is dependent on their ability to repress the activity of Smad proteins.
    He J; Tegen SB; Krawitz AR; Martin GS; Luo K
    J Biol Chem; 2003 Aug; 278(33):30540-7. PubMed ID: 12764135
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Bone morphogenetic protein-7 inhibits proximal tubular epithelial cell Smad3 signaling via increased SnoN expression.
    Luo DD; Phillips A; Fraser D
    Am J Pathol; 2010 Mar; 176(3):1139-47. PubMed ID: 20093492
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Cytoplasmic SnoN in normal tissues and nonmalignant cells antagonizes TGF-beta signaling by sequestration of the Smad proteins.
    Krakowski AR; Laboureau J; Mauviel A; Bissell MJ; Luo K
    Proc Natl Acad Sci U S A; 2005 Aug; 102(35):12437-42. PubMed ID: 16109768
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inability of transforming growth factor-beta to cause SnoN degradation leads to resistance to transforming growth factor-beta-induced growth arrest in esophageal cancer cells.
    Edmiston JS; Yeudall WA; Chung TD; Lebman DA
    Cancer Res; 2005 Jun; 65(11):4782-8. PubMed ID: 15930298
    [TBL] [Abstract][Full Text] [Related]  

  • 10. [Role of Ski/SnoN protein in the regulation of TGF-beta signal pathway].
    Lu ZH; Chen J
    Zhongguo Yi Xue Ke Xue Yuan Xue Bao; 2003 Apr; 25(2):233-6. PubMed ID: 12905729
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Negative feedback regulation of TGF-beta signaling by the SnoN oncoprotein.
    Stroschein SL; Wang W; Zhou S; Zhou Q; Luo K
    Science; 1999 Oct; 286(5440):771-4. PubMed ID: 10531062
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Up-regulated transcriptional repressors SnoN and Ski bind Smad proteins to antagonize transforming growth factor-beta signals during liver regeneration.
    Macias-Silva M; Li W; Leu JI; Crissey MA; Taub R
    J Biol Chem; 2002 Aug; 277(32):28483-90. PubMed ID: 12023281
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Arkadia activates Smad3/Smad4-dependent transcription by triggering signal-induced SnoN degradation.
    Levy L; Howell M; Das D; Harkin S; Episkopou V; Hill CS
    Mol Cell Biol; 2007 Sep; 27(17):6068-83. PubMed ID: 17591695
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The anaphase-promoting complex mediates TGF-beta signaling by targeting SnoN for destruction.
    Wan Y; Liu X; Kirschner MW
    Mol Cell; 2001 Nov; 8(5):1027-39. PubMed ID: 11741538
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The oncoprotein Ski acts as an antagonist of transforming growth factor-beta signaling by suppressing Smad2 phosphorylation.
    Prunier C; Pessah M; Ferrand N; Seo SR; Howe P; Atfi A
    J Biol Chem; 2003 Jul; 278(28):26249-57. PubMed ID: 12732634
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Efficient TGF-β/SMAD signaling in human melanoma cells associated with high c-SKI/SnoN expression.
    Javelaud D; van Kempen L; Alexaki VI; Le Scolan E; Luo K; Mauviel A
    Mol Cancer; 2011 Jan; 10(1):2. PubMed ID: 21211030
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Requirement for the SnoN oncoprotein in transforming growth factor beta-induced oncogenic transformation of fibroblast cells.
    Zhu Q; Pearson-White S; Luo K
    Mol Cell Biol; 2005 Dec; 25(24):10731-44. PubMed ID: 16314499
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Arkadia induces degradation of SnoN and c-Ski to enhance transforming growth factor-beta signaling.
    Nagano Y; Mavrakis KJ; Lee KL; Fujii T; Koinuma D; Sase H; Yuki K; Isogaya K; Saitoh M; Imamura T; Episkopou V; Miyazono K; Miyazawa K
    J Biol Chem; 2007 Jul; 282(28):20492-501. PubMed ID: 17510063
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Insulin-like growth factor-I inhibits transcriptional responses of transforming growth factor-beta by phosphatidylinositol 3-kinase/Akt-dependent suppression of the activation of Smad3 but not Smad2.
    Song K; Cornelius SC; Reiss M; Danielpour D
    J Biol Chem; 2003 Oct; 278(40):38342-51. PubMed ID: 12876289
    [TBL] [Abstract][Full Text] [Related]  

  • 20. SnoN is a cell type-specific mediator of transforming growth factor-beta responses.
    Sarker KP; Wilson SM; Bonni S
    J Biol Chem; 2005 Apr; 280(13):13037-46. PubMed ID: 15677458
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.