BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

203 related articles for article (PubMed ID: 10542278)

  • 1. Identification of hMutLbeta, a heterodimer of hMLH1 and hPMS1.
    Räschle M; Marra G; Nyström-Lahti M; Schär P; Jiricny J
    J Biol Chem; 1999 Nov; 274(45):32368-75. PubMed ID: 10542278
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Identification of a second MutL DNA mismatch repair complex (hPMS1 and hMLH1) in human epithelial cells.
    Leung WK; Kim JJ; Wu L; Sepulveda JL; Sepulveda AR
    J Biol Chem; 2000 May; 275(21):15728-32. PubMed ID: 10748105
    [TBL] [Abstract][Full Text] [Related]  

  • 3. N-terminus of hMLH1 confers interaction of hMutLalpha and hMutLbeta with hMutSalpha.
    Plotz G; Raedle J; Brieger A; Trojan J; Zeuzem S
    Nucleic Acids Res; 2003 Jun; 31(12):3217-26. PubMed ID: 12799449
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The interacting domains of three MutL heterodimers in man: hMLH1 interacts with 36 homologous amino acid residues within hMLH3, hPMS1 and hPMS2.
    Kondo E; Horii A; Fukushige S
    Nucleic Acids Res; 2001 Apr; 29(8):1695-702. PubMed ID: 11292842
    [TBL] [Abstract][Full Text] [Related]  

  • 5. ATM-mediated stabilization of hMutL DNA mismatch repair proteins augments p53 activation during DNA damage.
    Luo Y; Lin FT; Lin WC
    Mol Cell Biol; 2004 Jul; 24(14):6430-44. PubMed ID: 15226443
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Mutations within the hMLH1 and hPMS2 subunits of the human MutLalpha mismatch repair factor affect its ATPase activity, but not its ability to interact with hMutSalpha.
    Räschle M; Dufner P; Marra G; Jiricny J
    J Biol Chem; 2002 Jun; 277(24):21810-20. PubMed ID: 11948175
    [TBL] [Abstract][Full Text] [Related]  

  • 7. HNPCC mutations in the human DNA mismatch repair gene hMLH1 influence assembly of hMutLalpha and hMLH1-hEXO1 complexes.
    Jäger AC; Rasmussen M; Bisgaard HC; Singh KK; Nielsen FC; Rasmussen LJ
    Oncogene; 2001 Jun; 20(27):3590-5. PubMed ID: 11429708
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Expression of the DNA mismatch repair proteins hMLH1 and hPMS2 in normal human tissues.
    Fink D; Nebel S; Aebi S; Zheng H; Kim HK; Christen RD; Howell SB
    Br J Cancer; 1997; 76(7):890-3. PubMed ID: 9328148
    [TBL] [Abstract][Full Text] [Related]  

  • 9. hMutSalpha forms an ATP-dependent complex with hMutLalpha and hMutLbeta on DNA.
    Plotz G; Raedle J; Brieger A; Trojan J; Zeuzem S
    Nucleic Acids Res; 2002 Feb; 30(3):711-8. PubMed ID: 11809883
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Conditional nuclear localization of hMLH3 suggests a minor activity in mismatch repair and supports its role as a low-risk gene in HNPCC.
    Korhonen MK; Raevaara TE; Lohi H; Nyström M
    Oncol Rep; 2007 Feb; 17(2):351-4. PubMed ID: 17203173
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Somatic mutation of hPMS2 as a possible cause of sporadic human colon cancer with microsatellite instability.
    Ma AH; Xia L; Littman SJ; Swinler S; Lader G; Polinkovsky A; Olechnowicz J; Kasturi L; Lutterbaugh J; Modrich P; Veigl ML; Markowitz SD; Sedwick WD
    Oncogene; 2000 Apr; 19(18):2249-56. PubMed ID: 10822375
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Prevalence of germline mutations of hMLH1, hMSH2, hPMS1, hPMS2, and hMSH6 genes in 75 French kindreds with nonpolyposis colorectal cancer.
    Wang Q; Lasset C; Desseigne F; Saurin JC; Maugard C; Navarro C; Ruano E; Descos L; Trillet-Lenoir V; Bosset JF; Puisieux A
    Hum Genet; 1999; 105(1-2):79-85. PubMed ID: 10480359
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Transient mismatch repair gene transfection for functional analysis of genetic hMLH1 and hMSH2 variants.
    Brieger A; Trojan J; Raedle J; Plotz G; Zeuzem S
    Gut; 2002 Nov; 51(5):677-84. PubMed ID: 12377806
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The human PMS2L proteins do not interact with hMLH1, a major DNA mismatch repair protein.
    Kondo E; Horii A; Fukushige S
    J Biochem; 1999 Apr; 125(4):818-25. PubMed ID: 10101297
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Reduced expression of human mismatch repair genes in adult T-cell leukemia.
    Morimoto H; Tsukada J; Kominato Y; Tanaka Y
    Am J Hematol; 2005 Feb; 78(2):100-7. PubMed ID: 15682421
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Pathogenicity of the hereditary colorectal cancer mutation hMLH1 del616 linked to shortage of the functional protein.
    Raevaara TE; Vaccaro C; Abdel-Rahman WM; Mocetti E; Bala S; Lönnqvist KE; Kariola R; Lynch HT; Peltomäki P; Nyström-Lahti M
    Gastroenterology; 2003 Aug; 125(2):501-9. PubMed ID: 12891553
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mutations in mismatch repair genes are involved in the neoplastic transformation of human breast epithelial cells.
    Balogh GA; Russo IH; Russo J
    Int J Oncol; 2003 Aug; 23(2):411-9. PubMed ID: 12851690
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Human mismatch repair protein hMutLα is required to repair short slipped-DNAs of trinucleotide repeats.
    Panigrahi GB; Slean MM; Simard JP; Pearson CE
    J Biol Chem; 2012 Dec; 287(50):41844-50. PubMed ID: 23086927
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Expression of the MutL homologue hMLH3 in human cells and its role in DNA mismatch repair.
    Cannavo E; Marra G; Sabates-Bellver J; Menigatti M; Lipkin SM; Fischer F; Cejka P; Jiricny J
    Cancer Res; 2005 Dec; 65(23):10759-66. PubMed ID: 16322221
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Human colon cancer cells surviving high doses of cisplatin or oxaliplatin in vitro are not defective in DNA mismatch repair proteins.
    Sergent C; Franco N; Chapusot C; Lizard-Nacol S; Isambert N; Correia M; Chauffert B
    Cancer Chemother Pharmacol; 2002 Jun; 49(6):445-52. PubMed ID: 12107548
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.