BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

280 related articles for article (PubMed ID: 10543871)

  • 1. Antimalarial, antiproliferative, and antitumor activities of artemisinin-derived, chemically robust, trioxane dimers.
    Posner GH; Ploypradith P; Parker MH; O'Dowd H; Woo SH; Northrop J; Krasavin M; Dolan P; Kensler TW; Xie S; Shapiro TA
    J Med Chem; 1999 Oct; 42(21):4275-80. PubMed ID: 10543871
    [TBL] [Abstract][Full Text] [Related]  

  • 2. C-16 artemisinin derivatives and their antimalarial and cytotoxic activities: syntheses of artemisinin monomers, dimers, trimers, and tetramers by nucleophilic additions to artemisitene.
    Ekthawatchai S; Kamchonwongpaisan S; Kongsaeree P; Tarnchompoo B; Thebtaranonth Y; Yuthavong Y
    J Med Chem; 2001 Dec; 44(26):4688-95. PubMed ID: 11741486
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Antimalarial and antitumor evaluation of novel C-10 non-acetal dimers of 10beta-(2-hydroxyethyl)deoxoartemisinin.
    Jeyadevan JP; Bray PG; Chadwick J; Mercer AE; Byrne A; Ward SA; Park BK; Williams DP; Cosstick R; Davies J; Higson AP; Irving E; Posner GH; O'Neill PM
    J Med Chem; 2004 Feb; 47(5):1290-8. PubMed ID: 14971909
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Orally active, antimalarial, anticancer, artemisinin-derived trioxane dimers with high stability and efficacy.
    Posner GH; Paik IH; Sur S; McRiner AJ; Borstnik K; Xie S; Shapiro TA
    J Med Chem; 2003 Mar; 46(6):1060-5. PubMed ID: 12620083
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Novel ferrocenic artemisinin derivatives: synthesis, in vitro antimalarial activity and affinity of binding with ferroprotoporphyrin IX.
    Delhaes L; Blot C; Berry L; Maciejewski LA; Camus D; Brocard JS; Dive D
    Bioorg Med Chem; 2000 Dec; 8(12):2739-45. PubMed ID: 11131165
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Anticancer and antimalarial efficacy and safety of artemisinin-derived trioxane dimers in rodents.
    Posner GH; McRiner AJ; Paik IH; Sur S; Borstnik K; Xie S; Shapiro TA; Alagbala A; Foster B
    J Med Chem; 2004 Feb; 47(5):1299-301. PubMed ID: 14971910
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structure-activity relationships of lactone ring-opened analogs of the antimalarial 1,2,4-trioxane artemisinin.
    Posner GH; McGarvey DJ; Oh CH; Kumar N; Meshnick SR; Asawamahasadka W
    J Med Chem; 1995 Feb; 38(4):607-12. PubMed ID: 7861408
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis and antimalarial activities of fluoroalkyl derivatives of dihydroartemisinin.
    Thanh Nga TT; Ménage C; Bégué JP; Bonnet-Delpon D; Gantier JC; Pradines B; Doury JC; Thac TD
    J Med Chem; 1998 Oct; 41(21):4101-8. PubMed ID: 9767645
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Second generation, orally active, antimalarial, artemisinin-derived trioxane dimers with high stability, efficacy, and anticancer activity.
    Paik IH; Xie S; Shapiro TA; Labonte T; Narducci Sarjeant AA; Baege AC; Posner GH
    J Med Chem; 2006 May; 49(9):2731-4. PubMed ID: 16640333
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis and antimalarial activity of some 9-substituted artemisinin derivatives.
    Acton N; Karle JM; Miller RE
    J Med Chem; 1993 Aug; 36(17):2552-7. PubMed ID: 8355254
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Syntheses and antimalarial activities of 10-substituted deoxoartemisinins.
    Ma J; Katz E; Kyle DE; Ziffer H
    J Med Chem; 2000 Nov; 43(22):4228-32. PubMed ID: 11063619
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Recent advances in artemisinin and its derivatives as antimalarial and antitumor agents.
    Jung M; Lee K; Kim H; Park M
    Curr Med Chem; 2004 May; 11(10):1265-84. PubMed ID: 15134519
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Design, synthesis, derivatization, and structure-activity relationships of simplified, tricyclic, 1,2,4-trioxane alcohol analogues of the antimalarial artemisinin.
    Cumming JN; Wang D; Park SB; Shapiro TA; Posner GH
    J Med Chem; 1998 Mar; 41(6):952-64. PubMed ID: 9526569
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Trioxane dimers have potent antimalarial, antiproliferative and antitumor activities in vitro.
    Posner GH; Ploypradith P; Hapangama W; Wang D; Cumming JN; Dolan P; Kensler TW; Klinedinst D; Shapiro TA; Zheng QY; Murray CK; Pilkington LG; Jayasinghe LR; Bray JF; Daughenbaugh R
    Bioorg Med Chem; 1997 Jul; 5(7):1257-65. PubMed ID: 9377085
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis and biological evaluation of extraordinarily potent C-10 carba artemisinin dimers against P. falciparum malaria parasites and HL-60 cancer cells.
    Chadwick J; Mercer AE; Park BK; Cosstick R; O'Neill PM
    Bioorg Med Chem; 2009 Feb; 17(3):1325-38. PubMed ID: 19136263
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis and antimalarial activities of several fluorinated artemisinin derivatives.
    Pu YM; Torok DS; Ziffer H; Pan XQ; Meshnick SR
    J Med Chem; 1995 Sep; 38(20):4120-4. PubMed ID: 7562948
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Antitumor activity of novel deoxoartemisinin monomers, dimers, and trimer.
    Jung M; Lee S; Ham J; Lee K; Kim H; Kim SK
    J Med Chem; 2003 Mar; 46(6):987-94. PubMed ID: 12620075
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Mechanism-based development of new antimalarials: synthesis of derivatives of artemisinin attached to iron chelators.
    Kamchonwongpaisan S; Paitayatat S; Thebtaranonth Y; Wilairat P; Yuthavong Y
    J Med Chem; 1995 Jun; 38(13):2311-6. PubMed ID: 7608896
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Structure-activity relationships of the antimalarial agent artemisinin. 8. design, synthesis, and CoMFA studies toward the development of artemisinin-based drugs against leishmaniasis and malaria.
    Avery MA; Muraleedharan KM; Desai PV; Bandyopadhyaya AK; Furtado MM; Tekwani BL
    J Med Chem; 2003 Sep; 46(20):4244-58. PubMed ID: 13678403
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Chemistry of artemisinin: an overview.
    Webster HK; Lehnert EK
    Trans R Soc Trop Med Hyg; 1994 Jun; 88 Suppl 1():S27-9. PubMed ID: 8053019
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.