These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

431 related articles for article (PubMed ID: 10543890)

  • 1. Pyrrolobenzoxazepinone derivatives as non-nucleoside HIV-1 RT inhibitors: further structure-activity relationship studies and identification of more potent broad-spectrum HIV-1 RT inhibitors with antiviral activity.
    Campiani G; Morelli E; Fabbrini M; Nacci V; Greco G; Novellino E; Ramunno A; Maga G; Spadari S; Caliendo G; Bergamini A; Faggioli E; Uccella I; Bolacchi F; Marini S; Coletta M; Nacca A; Caccia S
    J Med Chem; 1999 Oct; 42(21):4462-70. PubMed ID: 10543890
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Specific targeting highly conserved residues in the HIV-1 reverse transcriptase primer grip region. Design, synthesis, and biological evaluation of novel, potent, and broad spectrum NNRTIs with antiviral activity.
    Fattorusso C; Gemma S; Butini S; Huleatt P; Catalanotti B; Persico M; De Angelis M; Fiorini I; Nacci V; Ramunno A; Rodriquez M; Greco G; Novellino E; Bergamini A; Marini S; Coletta M; Maga G; Spadari S; Campiani G
    J Med Chem; 2005 Nov; 48(23):7153-65. PubMed ID: 16279773
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Quinoxalinylethylpyridylthioureas (QXPTs) as potent non-nucleoside HIV-1 reverse transcriptase (RT) inhibitors. Further SAR studies and identification of a novel orally bioavailable hydrazine-based antiviral agent.
    Campiani G; Aiello F; Fabbrini M; Morelli E; Ramunno A; Armaroli S; Nacci V; Garofalo A; Greco G; Novellino E; Maga G; Spadari S; Bergamini A; Ventura L; Bongiovanni B; Capozzi M; Bolacchi F; Marini S; Coletta M; Guiso G; Caccia S
    J Med Chem; 2001 Feb; 44(3):305-15. PubMed ID: 11462972
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis and anti-HIV activity of 1,1,3-trioxo-2H,4H-thieno[3,4-e][1,2,4]thiadiazines (TTDs): a new family of HIV-1 specific non-nucleoside reverse transcriptase inhibitors.
    Arranz ME; Díaz JA; Ingate ST; Witvrouw M; Pannecouque C; Balzarini J; De Clercq E; Vega S
    Bioorg Med Chem; 1999 Dec; 7(12):2811-22. PubMed ID: 10658585
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Molecular design, synthesis and biological evaluation of BP-O-DAPY and O-DAPY derivatives as non-nucleoside HIV-1 reverse transcriptase inhibitors.
    Yang S; Pannecouque C; Daelemans D; Ma XD; Liu Y; Chen FE; De Clercq E
    Eur J Med Chem; 2013 Jul; 65():134-43. PubMed ID: 23707918
    [TBL] [Abstract][Full Text] [Related]  

  • 6. 4-Benzyl and 4-benzoyl-3-dimethylaminopyridin-2(1H)-ones: in vitro evaluation of new C-3-amino-substituted and C-5,6-alkyl-substituted analogues against clinically important HIV mutant strains.
    Benjahad A; Croisy M; Monneret C; Bisagni E; Mabire D; Coupa S; Poncelet A; Csoka I; Guillemont J; Meyer C; Andries K; Pauwels R; de Béthune MP; Himmel DM; Das K; Arnold E; Nguyen CH; Grierson DS
    J Med Chem; 2005 Mar; 48(6):1948-64. PubMed ID: 15771439
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Design, Synthesis, and Evaluation of Thiophene[3,2-d]pyrimidine Derivatives as HIV-1 Non-nucleoside Reverse Transcriptase Inhibitors with Significantly Improved Drug Resistance Profiles.
    Kang D; Fang Z; Li Z; Huang B; Zhang H; Lu X; Xu H; Zhou Z; Ding X; Daelemans D; De Clercq E; Pannecouque C; Zhan P; Liu X
    J Med Chem; 2016 Sep; 59(17):7991-8007. PubMed ID: 27541578
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Pyrido [1,2a] indole derivatives identified as novel non-nucleoside reverse transcriptase inhibitors of human immunodeficiency virus type 1.
    Taylor DL; Ahmed PS; Chambers P; Tyms AS; Bedard J; Duchaine J; Falardeau G; Lavallée JF; Brown W; Rando RF; Bowlin T
    Antivir Chem Chemother; 1999 Mar; 10(2):79-86. PubMed ID: 10335402
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Novel nonnucleoside inhibitors of HIV-1 reverse transcriptase. 8. 8-Aryloxymethyl- and 8-arylthiomethyldipyridodiazepinones.
    Cywin CL; Klunder JM; Hoermann M; Brickwood JR; David E; Grob PM; Schwartz R; Pauletti D; Barringer KJ; Shih CK; Sorge CL; Erickson DA; Joseph DP; Hattox SE
    J Med Chem; 1998 Jul; 41(16):2972-84. PubMed ID: 9685236
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Bioisosterism-based design and enantiomeric profiling of chiral hydroxyl-substituted biphenyl-diarylpyrimidine nonnucleoside HIV-1 reverse transcriptase inhibitors.
    Chen X; Ding L; Tao Y; Pannecouque C; De Clercq E; Zhuang C; Chen FE
    Eur J Med Chem; 2020 Sep; 202():112549. PubMed ID: 32712537
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Non-nucleoside HIV-1 reverse transcriptase inhibitors: synthesis and biological evaluation of novel quinoxalinylethylpyridylthioureas as potent antiviral agents.
    Campiani G; Fabbrini M; Morelli E; Nacci V; Greco G; Novellino E; Maga G; Spadari S; Bergamini A; Faggioli E; Uccella I; Bolacchi F; Marini S; Coletta M; Fracasso C; Caccia S
    Antivir Chem Chemother; 2000 Mar; 11(2):141-55. PubMed ID: 10819438
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Novel 8-substituted dipyridodiazepinone inhibitors with a broad-spectrum of activity against HIV-1 strains resistant to non-nucleoside reverse transcriptase inhibitors.
    O'Meara JA; Yoakim C; Bonneau PR; Bös M; Cordingley MG; Déziel R; Doyon L; Duan J; Garneau M; Guse I; Landry S; Malenfant E; Naud J; Ogilvie WW; Thavonekham B; Simoneau B
    J Med Chem; 2005 Aug; 48(17):5580-8. PubMed ID: 16107158
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Arylthiopyrrole (AThP) derivatives as non-nucleoside HIV-1 reverse transcriptase inhibitors: synthesis, structure-activity relationships, and docking studies (part 2).
    Lavecchia A; Costi R; Artico M; Miele G; Novellino E; Bergamini A; Crespan E; Maga G; Di Santo R
    ChemMedChem; 2006 Dec; 1(12):1379-90. PubMed ID: 17089434
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Pyrrolobenzothiazepinones and pyrrolobenzoxazepinones: novel and specific non-nucleoside HIV-1 reverse transcriptase inhibitors with antiviral activity.
    Campiani G; Nacci V; Fiorini I; De Filippis MP; Garofalo A; Greco G; Novellino E; Altamura S; Di Renzo L
    J Med Chem; 1996 Jul; 39(14):2672-80. PubMed ID: 8709096
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis and biological evaluation of piperidine-substituted triazine derivatives as HIV-1 non-nucleoside reverse transcriptase inhibitors.
    Chen X; Zhan P; Pannecouque C; Balzarini J; De Clercq E; Liu X
    Eur J Med Chem; 2012 May; 51():60-6. PubMed ID: 22405288
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis and biological evaluation of (±)-benzhydrol derivatives as potent non-nucleoside HIV-1 reverse transcriptase inhibitors.
    Ma XD; Zhang X; Yang SQ; Dai HF; Yang LM; Gu SX; Zheng YT; He QQ; Chen FE
    Bioorg Med Chem; 2011 Aug; 19(16):4704-9. PubMed ID: 21788138
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Design and synthesis of a new series of modified CH-diarylpyrimidines as drug-resistant HIV non-nucleoside reverse transcriptase inhibitors.
    Meng G; Liu Y; Zheng A; Chen F; Chen W; De Clercq E; Pannecouque C; Balzarini J
    Eur J Med Chem; 2014 Jul; 82():600-11. PubMed ID: 24952305
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis and biological activity of naphthyl-substituted (B-ring) benzophenone derivatives as novel non-nucleoside HIV-1 reverse transcriptase inhibitors.
    Ma XD; Zhang X; Dai HF; Yang SQ; Yang LM; Gu SX; Zheng YT; He QQ; Chen FE
    Bioorg Med Chem; 2011 Aug; 19(15):4601-7. PubMed ID: 21719299
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Selective targeting of the HIV-1 reverse transcriptase catalytic complex through interaction with the "primer grip" region by pyrrolobenzoxazepinone non-nucleoside inhibitors correlates with increased activity towards drug-resistant mutants.
    Zanoli S; Gemma S; Butini S; Brindisi M; Joshi BP; Campiani G; Fattorusso C; Persico M; Crespan E; Cancio R; Spadari S; Hübscher U; Maga G
    Biochem Pharmacol; 2008 Jul; 76(2):156-68. PubMed ID: 18541223
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis and biological activity of novel nonnucleoside inhibitors of HIV-1 reverse transcriptase. 2-Aryl-substituted benzimidazoles.
    Roth T; Morningstar ML; Boyer PL; Hughes SH; Buckheit RW; Michejda CJ
    J Med Chem; 1997 Dec; 40(26):4199-207. PubMed ID: 9435891
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 22.