241 related articles for article (PubMed ID: 10545171)
1. Crystal structure of Toxoplasma gondii hypoxanthine-guanine phosphoribosyltransferase with XMP, pyrophosphate, and two Mg(2+) ions bound: insights into the catalytic mechanism.
Héroux A; White EL; Ross LJ; Davis RL; Borhani DW
Biochemistry; 1999 Nov; 38(44):14495-506. PubMed ID: 10545171
[TBL] [Abstract][Full Text] [Related]
2. Crystal structures of the Toxoplasma gondii hypoxanthine-guanine phosphoribosyltransferase-GMP and -IMP complexes: comparison of purine binding interactions with the XMP complex.
Héroux A; White EL; Ross LJ; Borhani DW
Biochemistry; 1999 Nov; 38(44):14485-94. PubMed ID: 10545170
[TBL] [Abstract][Full Text] [Related]
3. Hypoxanthine guanine phosphoribosyltransferase distorts the purine ring of nucleotide substrates and perturbs the pKa of bound xanthosine monophosphate.
Gogia S; Balaram H; Puranik M
Biochemistry; 2011 May; 50(19):4184-93. PubMed ID: 21486037
[TBL] [Abstract][Full Text] [Related]
4. Alternative IMP binding in feedback inhibition of hypoxanthine-guanine phosphoribosyltransferase from Thermoanaerobacter tengcongensis.
Chen Q; Liang Y; Su X; Gu X; Zheng X; Luo M
J Mol Biol; 2005 May; 348(5):1199-210. PubMed ID: 15854655
[TBL] [Abstract][Full Text] [Related]
5. The crystal structure of free human hypoxanthine-guanine phosphoribosyltransferase reveals extensive conformational plasticity throughout the catalytic cycle.
Keough DT; Brereton IM; de Jersey J; Guddat LW
J Mol Biol; 2005 Aug; 351(1):170-81. PubMed ID: 15990111
[TBL] [Abstract][Full Text] [Related]
6. Altering the purine specificity of hypoxanthine-guanine-xanthine phosphoribosyltransferase from Tritrichomonas foetus by structure-based point mutations in the enzyme protein.
Munagala NR; Wang CC
Biochemistry; 1998 Nov; 37(47):16612-9. PubMed ID: 9843428
[TBL] [Abstract][Full Text] [Related]
7. Substrate deformation in a hypoxanthine-guanine phosphoribosyltransferase ternary complex: the structural basis for catalysis.
Héroux A; White EL; Ross LJ; Kuzin AP; Borhani DW
Structure; 2000 Dec; 8(12):1309-18. PubMed ID: 11188695
[TBL] [Abstract][Full Text] [Related]
8. Unusual substrate specificity of a chimeric hypoxanthine-guanine phosphoribosyltransferase containing segments from the Plasmodium falciparum and human enzymes.
Sujay Subbayya IN; Sukumaran S; Shivashankar K; Balaram H
Biochem Biophys Res Commun; 2000 Jun; 272(2):596-602. PubMed ID: 10833458
[TBL] [Abstract][Full Text] [Related]
9. Crystal structures of Apo and GMP bound hypoxanthine-guanine phosphoribosyltransferase from Legionella pneumophila and the implications in gouty arthritis.
Zhang N; Gong X; Lu M; Chen X; Qin X; Ge H
J Struct Biol; 2016 Jun; 194(3):311-6. PubMed ID: 26968365
[TBL] [Abstract][Full Text] [Related]
10. A transition-state analogue reduces protein dynamics in hypoxanthine-guanine phosphoribosyltransferase.
Wang F; Shi W; Nieves E; Angeletti RH; Schramm VL; Grubmeyer C
Biochemistry; 2001 Jul; 40(27):8043-54. PubMed ID: 11434773
[TBL] [Abstract][Full Text] [Related]
11. Catalysis in human hypoxanthine-guanine phosphoribosyltransferase: Asp 137 acts as a general acid/base.
Xu Y; Grubmeyer C
Biochemistry; 1998 Mar; 37(12):4114-24. PubMed ID: 9521733
[TBL] [Abstract][Full Text] [Related]
12. Crystal structure of a chimera of human and Plasmodium falciparum hypoxanthine guanine phosphoribosyltransferases provides insights into oligomerization.
Gayathri P; Sujay Subbayya IN; Ashok CS; Selvi TS; Balaram H; Murthy MR
Proteins; 2008 Dec; 73(4):1010-20. PubMed ID: 18536021
[TBL] [Abstract][Full Text] [Related]
13. Point mutations in the guanine phosphoribosyltransferase from Giardia lamblia modulate pyrophosphate binding and enzyme catalysis.
Page JP; Munagala NR; Wang CC
Eur J Biochem; 1999 Feb; 259(3):565-71. PubMed ID: 10092838
[TBL] [Abstract][Full Text] [Related]
14. Steady-state kinetics of the hypoxanthine-guanine-xanthine phosphoribosyltransferase from Tritrichomonas foetus: the role of threonine-47.
Munagala NR; Chin MS; Wang CC
Biochemistry; 1998 Mar; 37(12):4045-51. PubMed ID: 9521725
[TBL] [Abstract][Full Text] [Related]
15. Functional significance of four successive glycine residues in the pyrophosphate binding loop of fungal 6-oxopurine phosphoribosyltransferases.
Moynié L; Giraud MF; Breton A; Boissier F; Daignan-Fornier B; Dautant A
Protein Sci; 2012 Aug; 21(8):1185-96. PubMed ID: 22610485
[TBL] [Abstract][Full Text] [Related]
16. A single amino acid substitution in the human and a bacterial hypoxanthine phosphoribosyltransferase modulates specificity for the binding of guanine.
Lee CC; Craig SP; Eakin AE
Biochemistry; 1998 Mar; 37(10):3491-8. PubMed ID: 9521670
[TBL] [Abstract][Full Text] [Related]
17. Kinetic mechanism of human hypoxanthine-guanine phosphoribosyltransferase: rapid phosphoribosyl transfer chemistry.
Xu Y; Eads J; Sacchettini JC; Grubmeyer C
Biochemistry; 1997 Mar; 36(12):3700-12. PubMed ID: 9132023
[TBL] [Abstract][Full Text] [Related]
18. [Cloning, expression and characterization of the hypoxanthine-guanine phosphoribosyltransferase mutants from T. tengcongensis].
You DL; Qu H; Chen Q; Xing Y; Gu XC; Luo M
Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao (Shanghai); 2003 Sep; 35(9):853-8. PubMed ID: 12958660
[TBL] [Abstract][Full Text] [Related]
19. The 2.0 A structure of human hypoxanthine-guanine phosphoribosyltransferase in complex with a transition-state analog inhibitor.
Shi W; Li CM; Tyler PC; Furneaux RH; Grubmeyer C; Schramm VL; Almo SC
Nat Struct Biol; 1999 Jun; 6(6):588-93. PubMed ID: 10360366
[TBL] [Abstract][Full Text] [Related]
20. The conserved serine-tyrosine dipeptide in Leishmania donovani hypoxanthine-guanine phosphoribosyltransferase is essential for catalytic activity.
Jardim A; Ullman B
J Biol Chem; 1997 Apr; 272(14):8967-73. PubMed ID: 9083019
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
