These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

242 related articles for article (PubMed ID: 10545171)

  • 1. Crystal structure of Toxoplasma gondii hypoxanthine-guanine phosphoribosyltransferase with XMP, pyrophosphate, and two Mg(2+) ions bound: insights into the catalytic mechanism.
    Héroux A; White EL; Ross LJ; Davis RL; Borhani DW
    Biochemistry; 1999 Nov; 38(44):14495-506. PubMed ID: 10545171
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Crystal structures of the Toxoplasma gondii hypoxanthine-guanine phosphoribosyltransferase-GMP and -IMP complexes: comparison of purine binding interactions with the XMP complex.
    Héroux A; White EL; Ross LJ; Borhani DW
    Biochemistry; 1999 Nov; 38(44):14485-94. PubMed ID: 10545170
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Hypoxanthine guanine phosphoribosyltransferase distorts the purine ring of nucleotide substrates and perturbs the pKa of bound xanthosine monophosphate.
    Gogia S; Balaram H; Puranik M
    Biochemistry; 2011 May; 50(19):4184-93. PubMed ID: 21486037
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Alternative IMP binding in feedback inhibition of hypoxanthine-guanine phosphoribosyltransferase from Thermoanaerobacter tengcongensis.
    Chen Q; Liang Y; Su X; Gu X; Zheng X; Luo M
    J Mol Biol; 2005 May; 348(5):1199-210. PubMed ID: 15854655
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The crystal structure of free human hypoxanthine-guanine phosphoribosyltransferase reveals extensive conformational plasticity throughout the catalytic cycle.
    Keough DT; Brereton IM; de Jersey J; Guddat LW
    J Mol Biol; 2005 Aug; 351(1):170-81. PubMed ID: 15990111
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Altering the purine specificity of hypoxanthine-guanine-xanthine phosphoribosyltransferase from Tritrichomonas foetus by structure-based point mutations in the enzyme protein.
    Munagala NR; Wang CC
    Biochemistry; 1998 Nov; 37(47):16612-9. PubMed ID: 9843428
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Substrate deformation in a hypoxanthine-guanine phosphoribosyltransferase ternary complex: the structural basis for catalysis.
    Héroux A; White EL; Ross LJ; Kuzin AP; Borhani DW
    Structure; 2000 Dec; 8(12):1309-18. PubMed ID: 11188695
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Unusual substrate specificity of a chimeric hypoxanthine-guanine phosphoribosyltransferase containing segments from the Plasmodium falciparum and human enzymes.
    Sujay Subbayya IN; Sukumaran S; Shivashankar K; Balaram H
    Biochem Biophys Res Commun; 2000 Jun; 272(2):596-602. PubMed ID: 10833458
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Crystal structures of Apo and GMP bound hypoxanthine-guanine phosphoribosyltransferase from Legionella pneumophila and the implications in gouty arthritis.
    Zhang N; Gong X; Lu M; Chen X; Qin X; Ge H
    J Struct Biol; 2016 Jun; 194(3):311-6. PubMed ID: 26968365
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A transition-state analogue reduces protein dynamics in hypoxanthine-guanine phosphoribosyltransferase.
    Wang F; Shi W; Nieves E; Angeletti RH; Schramm VL; Grubmeyer C
    Biochemistry; 2001 Jul; 40(27):8043-54. PubMed ID: 11434773
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Catalysis in human hypoxanthine-guanine phosphoribosyltransferase: Asp 137 acts as a general acid/base.
    Xu Y; Grubmeyer C
    Biochemistry; 1998 Mar; 37(12):4114-24. PubMed ID: 9521733
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Crystal structure of a chimera of human and Plasmodium falciparum hypoxanthine guanine phosphoribosyltransferases provides insights into oligomerization.
    Gayathri P; Sujay Subbayya IN; Ashok CS; Selvi TS; Balaram H; Murthy MR
    Proteins; 2008 Dec; 73(4):1010-20. PubMed ID: 18536021
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Point mutations in the guanine phosphoribosyltransferase from Giardia lamblia modulate pyrophosphate binding and enzyme catalysis.
    Page JP; Munagala NR; Wang CC
    Eur J Biochem; 1999 Feb; 259(3):565-71. PubMed ID: 10092838
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Steady-state kinetics of the hypoxanthine-guanine-xanthine phosphoribosyltransferase from Tritrichomonas foetus: the role of threonine-47.
    Munagala NR; Chin MS; Wang CC
    Biochemistry; 1998 Mar; 37(12):4045-51. PubMed ID: 9521725
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Functional significance of four successive glycine residues in the pyrophosphate binding loop of fungal 6-oxopurine phosphoribosyltransferases.
    Moynié L; Giraud MF; Breton A; Boissier F; Daignan-Fornier B; Dautant A
    Protein Sci; 2012 Aug; 21(8):1185-96. PubMed ID: 22610485
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A single amino acid substitution in the human and a bacterial hypoxanthine phosphoribosyltransferase modulates specificity for the binding of guanine.
    Lee CC; Craig SP; Eakin AE
    Biochemistry; 1998 Mar; 37(10):3491-8. PubMed ID: 9521670
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Kinetic mechanism of human hypoxanthine-guanine phosphoribosyltransferase: rapid phosphoribosyl transfer chemistry.
    Xu Y; Eads J; Sacchettini JC; Grubmeyer C
    Biochemistry; 1997 Mar; 36(12):3700-12. PubMed ID: 9132023
    [TBL] [Abstract][Full Text] [Related]  

  • 18. [Cloning, expression and characterization of the hypoxanthine-guanine phosphoribosyltransferase mutants from T. tengcongensis].
    You DL; Qu H; Chen Q; Xing Y; Gu XC; Luo M
    Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao (Shanghai); 2003 Sep; 35(9):853-8. PubMed ID: 12958660
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The 2.0 A structure of human hypoxanthine-guanine phosphoribosyltransferase in complex with a transition-state analog inhibitor.
    Shi W; Li CM; Tyler PC; Furneaux RH; Grubmeyer C; Schramm VL; Almo SC
    Nat Struct Biol; 1999 Jun; 6(6):588-93. PubMed ID: 10360366
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The conserved serine-tyrosine dipeptide in Leishmania donovani hypoxanthine-guanine phosphoribosyltransferase is essential for catalytic activity.
    Jardim A; Ullman B
    J Biol Chem; 1997 Apr; 272(14):8967-73. PubMed ID: 9083019
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.