324 related articles for article (PubMed ID: 10545177)
1. Role of disulfide bonds in the structure and potassium channel blocking activity of ShK toxin.
Pennington MW; Lanigan MD; Kalman K; Mahnir VM; Rauer H; McVaugh CT; Behm D; Donaldson D; Chandy KG; Kem WR; Norton RS
Biochemistry; 1999 Nov; 38(44):14549-58. PubMed ID: 10545177
[TBL] [Abstract][Full Text] [Related]
2. Designed peptide analogues of the potassium channel blocker ShK toxin.
Lanigan MD; Pennington MW; Lefievre Y; Rauer H; Norton RS
Biochemistry; 2001 Dec; 40(51):15528-37. PubMed ID: 11747428
[TBL] [Abstract][Full Text] [Related]
3. A potassium-channel toxin from the sea anemone Bunodosoma granulifera, an inhibitor for Kv1 channels. Revision of the amino acid sequence, disulfide-bridge assignment, chemical synthesis, and biological activity.
Cotton J; Crest M; Bouet F; Alessandri N; Gola M; Forest E; Karlsson E; Castañeda O; Harvey AL; Vita C; Ménez A
Eur J Biochem; 1997 Feb; 244(1):192-202. PubMed ID: 9063464
[TBL] [Abstract][Full Text] [Related]
4. N-Terminally extended analogues of the K⁺ channel toxin from Stichodactyla helianthus as potent and selective blockers of the voltage-gated potassium channel Kv1.3.
Chang SC; Huq R; Chhabra S; Beeton C; Pennington MW; Smith BJ; Norton RS
FEBS J; 2015 Jun; 282(12):2247-59. PubMed ID: 25864722
[TBL] [Abstract][Full Text] [Related]
5. Chemical synthesis and characterization of ShK toxin: a potent potassium channel inhibitor from a sea anemone.
Pennington MW; Byrnes ME; Zaydenberg I; Khaytin I; de Chastonay J; Krafte DS; Hill R; Mahnir VM; Volberg WA; Gorczyca W
Int J Pept Protein Res; 1995 Nov; 46(5):354-8. PubMed ID: 8567178
[TBL] [Abstract][Full Text] [Related]
6. Structural conservation of the pores of calcium-activated and voltage-gated potassium channels determined by a sea anemone toxin.
Rauer H; Pennington M; Cahalan M; Chandy KG
J Biol Chem; 1999 Jul; 274(31):21885-92. PubMed ID: 10419508
[TBL] [Abstract][Full Text] [Related]
7. Conformational exchange in the potassium channel blocker ShK.
Iwakawa N; Baxter NJ; Wai DCC; Fowler NJ; Morales RAV; Sugase K; Norton RS; Williamson MP
Sci Rep; 2019 Dec; 9(1):19307. PubMed ID: 31848433
[TBL] [Abstract][Full Text] [Related]
8. Mutating a critical lysine in ShK toxin alters its binding configuration in the pore-vestibule region of the voltage-gated potassium channel, Kv1.3.
Lanigan MD; Kalman K; Lefievre Y; Pennington MW; Chandy KG; Norton RS
Biochemistry; 2002 Oct; 41(40):11963-71. PubMed ID: 12356296
[TBL] [Abstract][Full Text] [Related]
9. The D-diastereomer of ShK toxin selectively blocks voltage-gated K+ channels and inhibits T lymphocyte proliferation.
Beeton C; Smith BJ; Sabo JK; Crossley G; Nugent D; Khaytin I; Chi V; Chandy KG; Pennington MW; Norton RS
J Biol Chem; 2008 Jan; 283(2):988-97. PubMed ID: 17984097
[TBL] [Abstract][Full Text] [Related]
10. Potassium channel blockade by the sea anemone toxin ShK for the treatment of multiple sclerosis and other autoimmune diseases.
Norton RS; Pennington MW; Wulff H
Curr Med Chem; 2004 Dec; 11(23):3041-52. PubMed ID: 15578998
[TBL] [Abstract][Full Text] [Related]
11. Maurotoxin and the Kv1.1 channel: voltage-dependent binding upon enantiomerization of the scorpion toxin disulfide bridge Cys31-Cys34.
Lecomte C; Ben Khalifa R; Martin-Eauclaire MF; Kharrat R; El Ayeb M; Darbon H; Rochat H; Crest M; Sabatier JM
J Pept Res; 2000 Mar; 55(3):246-54. PubMed ID: 10727107
[TBL] [Abstract][Full Text] [Related]
12. Characterization of a potassium channel toxin from the Caribbean Sea anemone Stichodactyla helianthus.
Castañeda O; Sotolongo V; Amor AM; Stöcklin R; Anderson AJ; Harvey AL; Engström A; Wernstedt C; Karlsson E
Toxicon; 1995 May; 33(5):603-13. PubMed ID: 7660365
[TBL] [Abstract][Full Text] [Related]
13. Structure, folding and stability of a minimal homologue from Anemonia sulcata of the sea anemone potassium channel blocker ShK.
Krishnarjuna B; MacRaild CA; Sunanda P; Morales RAV; Peigneur S; Macrander J; Yu HH; Daly M; Raghothama S; Dhawan V; Chauhan S; Tytgat J; Pennington MW; Norton RS
Peptides; 2018 Jan; 99():169-178. PubMed ID: 28993277
[TBL] [Abstract][Full Text] [Related]
14. ShK-Dap22, a potent Kv1.3-specific immunosuppressive polypeptide.
Kalman K; Pennington MW; Lanigan MD; Nguyen A; Rauer H; Mahnir V; Paschetto K; Kem WR; Grissmer S; Gutman GA; Christian EP; Cahalan MD; Norton RS; Chandy KG
J Biol Chem; 1998 Dec; 273(49):32697-707. PubMed ID: 9830012
[TBL] [Abstract][Full Text] [Related]
15. Substitution of a single residue in Stichodactyla helianthus peptide, ShK-Dap22, reveals a novel pharmacological profile.
Middleton RE; Sanchez M; Linde AR; Bugianesi RM; Dai G; Felix JP; Koprak SL; Staruch MJ; Bruguera M; Cox R; Ghosh A; Hwang J; Jones S; Kohler M; Slaughter RS; McManus OB; Kaczorowski GJ; Garcia ML
Biochemistry; 2003 Nov; 42(46):13698-707. PubMed ID: 14622016
[TBL] [Abstract][Full Text] [Related]
16. Ionisation behaviour and solution properties of the potassium-channel blocker ShK toxin.
Tudor JE; Pennington MW; Norton RS
Eur J Biochem; 1998 Jan; 251(1-2):133-41. PubMed ID: 9492277
[TBL] [Abstract][Full Text] [Related]
17. Identification of residues in dendrotoxin K responsible for its discrimination between neuronal K+ channels containing Kv1.1 and 1.2 alpha subunits.
Wang FC; Bell N; Reid P; Smith LA; McIntosh P; Robertson B; Dolly JO
Eur J Biochem; 1999 Jul; 263(1):222-9. PubMed ID: 10429207
[TBL] [Abstract][Full Text] [Related]
18. Synthesis and characterization of leiurotoxin I analogs lacking one disulfide bridge: evidence that disulfide pairing 3-21 is not required for full toxin activity.
Sabatier JM; Lecomte C; Mabrouk K; Darbon H; Oughideni R; Canarelli S; Rochat H; Martin-Eauclaire MF; van Rietschoten J
Biochemistry; 1996 Aug; 35(33):10641-7. PubMed ID: 8718853
[TBL] [Abstract][Full Text] [Related]
19. Identification of three separate binding sites on SHK toxin, a potent inhibitor of voltage-dependent potassium channels in human T-lymphocytes and rat brain.
Pennington MW; Mahnir VM; Krafte DS; Zaydenberg I; Byrnes ME; Khaytin I; Crowley K; Kem WR
Biochem Biophys Res Commun; 1996 Feb; 219(3):696-701. PubMed ID: 8645244
[TBL] [Abstract][Full Text] [Related]
20. Affinity and selectivity of ShK toxin for the Kv1 potassium channels from free energy simulations.
Rashid MH; Kuyucak S
J Phys Chem B; 2012 Apr; 116(16):4812-22. PubMed ID: 22480371
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
