139 related articles for article (PubMed ID: 10545419)
1. Transport of the cooked-food mutagen 2-amino-1-methyl-6-phenylimidazo-[4,5-b]pyridine (PhIP) across the human intestinal Caco-2 cell monolayer: role of efflux pumps.
Walle UK; Walle T
Carcinogenesis; 1999 Nov; 20(11):2153-7. PubMed ID: 10545419
[TBL] [Abstract][Full Text] [Related]
2. Caffeic acid inhibits the uptake of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) by inducing the efflux transporters expression in Caco-2 cells.
Hong YJ; Yang SY; Nam MH; Koo YC; Lee KW
Biol Pharm Bull; 2015; 38(2):201-7. PubMed ID: 25399682
[TBL] [Abstract][Full Text] [Related]
3. An in vitro and in silico study on the flavonoid-mediated modulation of the transport of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) through Caco-2 monolayers.
Schutte ME; Freidig AP; van de Sandt JJ; Alink GM; Rietjens IM; Groten JP
Toxicol Appl Pharmacol; 2006 Dec; 217(2):204-15. PubMed ID: 16997339
[TBL] [Abstract][Full Text] [Related]
4. The H2 receptor antagonist nizatidine is a P-glycoprotein substrate: characterization of its intestinal epithelial cell efflux transport.
Dahan A; Sabit H; Amidon GL
AAPS J; 2009 Jun; 11(2):205-13. PubMed ID: 19319690
[TBL] [Abstract][Full Text] [Related]
5. Myricetin stimulates the absorption of the pro-carcinogen PhIP.
Schutte ME; van de Sandt JJ; Alink GM; Groten JP; Rietjens IM
Cancer Lett; 2006 Jan; 231(1):36-42. PubMed ID: 16356829
[TBL] [Abstract][Full Text] [Related]
6. Effects of chlorophyllin on transport of dibenzo(a, l)pyrene, 2-amino-1-methyl-6-phenylimidazo-[4,5-b]pyridine, and aflatoxin B(1) across Caco-2 cell monolayers.
Mata JE; Yu Z; Gray JE; Williams DE; Rodriguez-Proteau R
Toxicology; 2004 Mar; 196(1-2):117-25. PubMed ID: 15036761
[TBL] [Abstract][Full Text] [Related]
7. Effects of flavonoid mixtures on the transport of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) through Caco-2 monolayers: an in vitro and kinetic modeling approach to predict the combined effects on transporter inhibition.
Schutte ME; Boersma MG; Verhallen DA; Groten JP; Rietjens IM
Food Chem Toxicol; 2008 Feb; 46(2):557-66. PubMed ID: 17935851
[TBL] [Abstract][Full Text] [Related]
8. Intra- and interindividual variability in systemic exposure in humans to 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline and 2-amino-1-methyl- 6-phenylimidazo[4,5-b]pyridine, carcinogens present in cooked beef.
Lynch AM; Knize MG; Boobis AR; Gooderham NJ; Davies DS; Murray S
Cancer Res; 1992 Nov; 52(22):6216-23. PubMed ID: 1423264
[TBL] [Abstract][Full Text] [Related]
9. Bioactivation of the cooked food mutagen N-hydroxy-2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine by estrogen sulfotransferase in cultured human mammary epithelial cells.
Lewis AJ; Walle UK; King RS; Kadlubar FF; Falany CN; Walle T
Carcinogenesis; 1998 Nov; 19(11):2049-53. PubMed ID: 9855023
[TBL] [Abstract][Full Text] [Related]
10. Cytotoxicity, DNA adduct formation and DNA repair induced by 2-hydroxyamino-3-methylimidazo[4,5-f]quinoline and 2-hydroxyamino-1-methyl-6-phenylimidazo[4,5-b]pyridine in cultured human mammary epithelial cells.
Fan L; Schut HA; Snyderwine EG
Carcinogenesis; 1995 Apr; 16(4):775-9. PubMed ID: 7728954
[TBL] [Abstract][Full Text] [Related]
11. The breast cancer resistance protein (Bcrp1/Abcg2) restricts exposure to the dietary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine.
van Herwaarden AE; Jonker JW; Wagenaar E; Brinkhuis RF; Schellens JH; Beijnen JH; Schinkel AH
Cancer Res; 2003 Oct; 63(19):6447-52. PubMed ID: 14559835
[TBL] [Abstract][Full Text] [Related]
12. The colon carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) is actively secreted in the distal colon of the rat: an integrated view on the role of PhIP transport and metabolism in PhIP-induced colon carcinogenesis.
Nicken P; Schröder B; von Keutz A; Breves G; Steinberg P
Arch Toxicol; 2013 May; 87(5):895-904. PubMed ID: 23306951
[TBL] [Abstract][Full Text] [Related]
13. Development of an online-SPE-LC-MS method for the investigation of the intestinal absorption of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PHIP) and its bacterial metabolite PHIP-M1 in a Caco-2 Transwell system.
Willenberg I; von Elsner L; Steinberg P; Schebb NH
Food Chem; 2015 Jan; 166():537-543. PubMed ID: 25053091
[TBL] [Abstract][Full Text] [Related]
14. The capability of rat colon tissue slices to metabolize the cooked-food carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine.
Malfatti MA; Connors MS; Mauthe RJ; Felton JS
Cancer Res; 1996 Jun; 56(11):2550-5. PubMed ID: 8653696
[TBL] [Abstract][Full Text] [Related]
15. Transport and metabolism of the tea flavonoid (-)-epicatechin by the human intestinal cell line Caco-2.
Vaidyanathan JB; Walle T
Pharm Res; 2001 Oct; 18(10):1420-5. PubMed ID: 11697467
[TBL] [Abstract][Full Text] [Related]
16. Investigation of the effects of soluble fibers on the absorption of resveratrol and 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PHIP) in the Caco-2 cellular model of intestinal absorption.
Willenberg I; Wonik J; Schebb NH
Int J Food Sci Nutr; 2015; 66(6):677-9. PubMed ID: 26307510
[TBL] [Abstract][Full Text] [Related]
17. Increased bioavailability of the food-derived carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in MRP2-deficient rats.
Dietrich CG; de Waart DR; Ottenhoff R; Schoots IG; Elferink RP
Mol Pharmacol; 2001 May; 59(5):974-80. PubMed ID: 11306678
[TBL] [Abstract][Full Text] [Related]
18. Mechanisms of transport and structure-permeability relationship of sulfasalazine and its analogs in Caco-2 cell monolayers.
Liang E; Proudfoot J; Yazdanian M
Pharm Res; 2000 Oct; 17(10):1168-74. PubMed ID: 11145220
[TBL] [Abstract][Full Text] [Related]
19. Metabolic processing and disposition of 2-amino-3-methylimidazo[4,5-f] quinoline (IQ), 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx), and 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in nonhuman primates.
Snyderwine EG; Turesky RJ; Buonarati MH; Turteltaub KW; Adamson RH
Princess Takamatsu Symp; 1995; 23():69-77. PubMed ID: 8844797
[TBL] [Abstract][Full Text] [Related]
20. Neonatal exposure to the food mutagen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine via breast milk or directly induces intestinal tumors in multiple intestinal neoplasia mice.
Paulsen JE; Steffensen IL; Andreassen A; Vikse R; Alexander J
Carcinogenesis; 1999 Jul; 20(7):1277-82. PubMed ID: 10383901
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]