These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

150 related articles for article (PubMed ID: 10551862)

  • 21. Mutation of Gly717Phe in human topoisomerase 1B has an effect on enzymatic function, reactivity to the camptothecin anticancer drug and on the linker domain orientation.
    Wang Z; D'Annessa I; Tesauro C; Croce S; Ottaviani A; Fiorani P; Desideri A
    Biochim Biophys Acta; 2015 Aug; 1854(8):860-8. PubMed ID: 25910424
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Indispensable, functionally complementing N and C-terminal domains constitute site-specific topoisomerase I.
    Jain P; Nagaraja V
    J Mol Biol; 2006 Apr; 357(5):1409-21. PubMed ID: 16490213
    [TBL] [Abstract][Full Text] [Related]  

  • 23. The human topoisomerase 1B Arg634Ala mutation results in camptothecin resistance and loss of inter-domain motion correlation.
    D'Annessa I; Tesauro C; Wang Z; Arnò B; Zuccaro L; Fiorani P; Desideri A
    Biochim Biophys Acta; 2013 Dec; 1834(12):2712-21. PubMed ID: 24096022
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Structural insights into the function of type IB topoisomerases.
    Redinbo MR; Champoux JJ; Hol WG
    Curr Opin Struct Biol; 1999 Feb; 9(1):29-36. PubMed ID: 10047584
    [TBL] [Abstract][Full Text] [Related]  

  • 25. An engineered mutant of vaccinia virus DNA topoisomerase I is sensitive to the anti-cancer drug camptothecin.
    Gupta M; Zhu CX; Tse-Dinh YC
    J Biol Chem; 1992 Dec; 267(34):24177-80. PubMed ID: 1332948
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Camptothecin-sensitive relaxation of supercoiled DNA by the topoisomerase I-like activity associated with poly(ADP-ribose) polymerase-1.
    Yung TM; Parent M; Ho EL; Satoh MS
    J Biol Chem; 2004 Mar; 279(12):11992-9. PubMed ID: 14715657
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Homocamptothecin, an E-ring-modified camptothecin analogue, generates new topoisomerase I-mediated DNA breaks.
    Bailly C; Lansiaux A; Dassonneville L; Demarquay D; Coulomb H; Huchet M; Lavergne O; Bigg DC
    Biochemistry; 1999 Nov; 38(47):15556-63. PubMed ID: 10569939
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Enhanced CPT sensitivity of yeast cells and selective relaxation of Ga14 motif-containing DNA by novel Gal4-topoisomerase I fusion proteins.
    Alessandri M; Beretta GL; Ferretti E; Mancia A; Khobta A; Capranico G
    J Mol Biol; 2004 Mar; 337(2):295-305. PubMed ID: 15003448
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Disulfide cross-links reveal conserved features of DNA topoisomerase I architecture and a role for the N terminus in clamp closure.
    Palle K; Pattarello L; van der Merwe M; Losasso C; Benedetti P; Bjornsti MA
    J Biol Chem; 2008 Oct; 283(41):27767-27775. PubMed ID: 18693244
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Single-Molecule Supercoil Relaxation Assay as a Screening Tool to Determine the Mechanism and Efficacy of Human Topoisomerase IB Inhibitors.
    Seol Y; Zhang H; Agama K; Lorence N; Pommier Y; Neuman KC
    Mol Cancer Ther; 2015 Nov; 14(11):2552-9. PubMed ID: 26351326
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Structural and functional interactions of the prostate cancer suppressor protein NKX3.1 with topoisomerase I.
    Song LN; Bowen C; Gelmann EP
    Biochem J; 2013 Jul; 453(1):125-36. PubMed ID: 23557481
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Dumbbell-shaped circular oligonucleotides as inhibitors of human topoisomerase I.
    Li X; Tao Ng MT; Wang Y; Liu X; Li T
    Bioorg Med Chem Lett; 2007 Sep; 17(17):4967-71. PubMed ID: 17591440
    [TBL] [Abstract][Full Text] [Related]  

  • 33. DNA contacts by protein domains of the molluscum contagiosum virus type-1B topoisomerase.
    Hwang Y; Park M; Fischer WH; Burgin A; Bushman F
    Virology; 1999 Sep; 262(2):479-91. PubMed ID: 10502526
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Human DNA topoisomerase I: quantitative analysis of the effects of camptothecin analogs and the benzophenanthridine alkaloids nitidine and 6-ethoxydihydronitidine on DNA topoisomerase I-induced DNA strand breakage.
    Holden JA; Wall ME; Wani MC; Manikumar G
    Arch Biochem Biophys; 1999 Oct; 370(1):66-76. PubMed ID: 10496978
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Role of the linker domain and the 203-214 N-terminal residues in the human topoisomerase I DNA complex dynamics.
    Chillemi G; Redinbo M; Bruselles A; Desideri A
    Biophys J; 2004 Dec; 87(6):4087-97. PubMed ID: 15347588
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Identification of a minimal functional linker in human topoisomerase I by domain swapping with Cre recombinase.
    Frøhlich RF; Juul S; Nielsen MB; Vinther M; Veigaard C; Hede MS; Andersen FF
    Biochemistry; 2008 Jul; 47(27):7127-36. PubMed ID: 18553933
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Characterization of a mammalian mutant with a camptothecin-resistant DNA topoisomerase I.
    Andoh T; Ishii K; Suzuki Y; Ikegami Y; Kusunoki Y; Takemoto Y; Okada K
    Proc Natl Acad Sci U S A; 1987 Aug; 84(16):5565-9. PubMed ID: 3039492
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Structure-based analysis of the effects of camptothecin on the activities of human topoisomerase I.
    Champoux JJ
    Ann N Y Acad Sci; 2000; 922():56-64. PubMed ID: 11193925
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Characterization of DNA Binding by the Isolated N-Terminal Domain of Vaccinia Virus DNA Topoisomerase IB.
    Reed B; Yakovleva L; Shuman S; Ghose R
    Biochemistry; 2017 Jul; 56(26):3307-3317. PubMed ID: 28570045
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Structural basis for specificity in the poxvirus topoisomerase.
    Perry K; Hwang Y; Bushman FD; Van Duyne GD
    Mol Cell; 2006 Aug; 23(3):343-54. PubMed ID: 16885024
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 8.