BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

217 related articles for article (PubMed ID: 10551880)

  • 1. Characterization of four mammalian numb protein isoforms. Identification of cytoplasmic and membrane-associated variants of the phosphotyrosine binding domain.
    Dho SE; French MB; Woods SA; McGlade CJ
    J Biol Chem; 1999 Nov; 274(46):33097-104. PubMed ID: 10551880
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The mammalian numb phosphotyrosine-binding domain. Characterization of binding specificity and identification of a novel PDZ domain-containing numb binding protein, LNX.
    Dho SE; Jacob S; Wolting CD; French MB; Rohrschneider LR; McGlade CJ
    J Biol Chem; 1998 Apr; 273(15):9179-87. PubMed ID: 9535908
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A novel PTB-PDZ domain interaction mediates isoform-specific ubiquitylation of mammalian Numb.
    Nie J; Li SS; McGlade CJ
    J Biol Chem; 2004 May; 279(20):20807-15. PubMed ID: 14990566
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Numb endocytic adapter proteins regulate the transport and processing of the amyloid precursor protein in an isoform-dependent manner: implications for Alzheimer disease pathogenesis.
    Kyriazis GA; Wei Z; Vandermey M; Jo DG; Xin O; Mattson MP; Chan SL
    J Biol Chem; 2008 Sep; 283(37):25492-25502. PubMed ID: 18599481
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Numb isoforms containing a short PTB domain promote neurotrophic factor-induced differentiation and neurotrophic factor withdrawal-induced death of PC12 Cells.
    Pedersen WA; Chan SL; Zhu H; Abdur-Rahman LA; Verdi JM; Mattson MP
    J Neurochem; 2002 Aug; 82(4):976-86. PubMed ID: 12358803
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Evidence for altered Numb isoform levels in Alzheimer's disease patients and a triple transgenic mouse model.
    Chigurupati S; Madan M; Okun E; Wei Z; Pattisapu JV; Mughal MR; Mattson MP; Chan SL
    J Alzheimers Dis; 2011; 24(2):349-61. PubMed ID: 21258150
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A novel transmembrane protein recruits numb to the plasma membrane during asymmetric cell division.
    Qin H; Percival-Smith A; Li C; Jia CY; Gloor G; Li SS
    J Biol Chem; 2004 Mar; 279(12):11304-12. PubMed ID: 14670962
    [TBL] [Abstract][Full Text] [Related]  

  • 8. LNX functions as a RING type E3 ubiquitin ligase that targets the cell fate determinant Numb for ubiquitin-dependent degradation.
    Nie J; McGill MA; Dermer M; Dho SE; Wolting CD; McGlade CJ
    EMBO J; 2002 Jan; 21(1-2):93-102. PubMed ID: 11782429
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Asymmetric localization of Numb:EGFP in dividing neuroepithelial cells during neurulation in Danio rerio.
    Reugels AM; Boggetti B; Scheer N; Campos-Ortega JA
    Dev Dyn; 2006 Apr; 235(4):934-48. PubMed ID: 16493689
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Dynamic regulation of mammalian numb by G protein-coupled receptors and protein kinase C activation: Structural determinants of numb association with the cortical membrane.
    Dho SE; Trejo J; Siderovski DP; McGlade CJ
    Mol Biol Cell; 2006 Sep; 17(9):4142-55. PubMed ID: 16837553
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Functional analysis of the Numb phosphotyrosine-binding domain using site-directed mutagenesis.
    Yaich L; Ooi J; Park M; Borg JP; Landry C; Bodmer R; Margolis B
    J Biol Chem; 1998 Apr; 273(17):10381-8. PubMed ID: 9553095
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Characterization and role of NUMB in the human extravillous trophopblast.
    Haider M; Qiu Q; Bani-Yaghoub M; Tsang BK; Gruslin A
    Placenta; 2011 Jun; 32(6):441-9. PubMed ID: 21486681
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A novel adapter protein employs a phosphotyrosine binding domain and exceptionally basic N-terminal domains to capture and localize an atypical protein kinase C: characterization of Caenorhabditis elegans C kinase adapter 1, a protein that avidly binds protein kinase C3.
    Zhang L; Wu SL; Rubin CS
    J Biol Chem; 2001 Mar; 276(13):10463-75. PubMed ID: 11134024
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Identification and selected reaction monitoring (SRM) quantification of endocytosis factors associated with Numb.
    Krieger JR; Taylor P; Gajadhar AS; Guha A; Moran MF; McGlade CJ
    Mol Cell Proteomics; 2013 Feb; 12(2):499-514. PubMed ID: 23211419
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Protein 4.1-mediated membrane targeting of human discs large in epithelial cells.
    Hanada T; Takeuchi A; Sondarva G; Chishti AH
    J Biol Chem; 2003 Sep; 278(36):34445-50. PubMed ID: 12807908
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mammalian NUMB is an evolutionarily conserved signaling adapter protein that specifies cell fate.
    Verdi JM; Schmandt R; Bashirullah A; Jacob S; Salvino R; Craig CG; Program AE; Lipshitz HD; McGlade CJ
    Curr Biol; 1996 Sep; 6(9):1134-45. PubMed ID: 8805372
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Numb modifies neuronal vulnerability to amyloid beta-peptide in an isoform-specific manner by a mechanism involving altered calcium homeostasis: implications for neuronal death in Alzheimer's disease.
    Chan SL; Pedersen WA; Zhu H; Mattson MP
    Neuromolecular Med; 2002; 1(1):55-67. PubMed ID: 12025816
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The Lnx family proteins function as molecular scaffolds for Numb family proteins.
    Rice DS; Northcutt GM; Kurschner C
    Mol Cell Neurosci; 2001 Nov; 18(5):525-40. PubMed ID: 11922143
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Structure of a Numb PTB domain-peptide complex suggests a basis for diverse binding specificity.
    Li SC; Zwahlen C; Vincent SJ; McGlade CJ; Kay LE; Pawson T; Forman-Kay JD
    Nat Struct Biol; 1998 Dec; 5(12):1075-83. PubMed ID: 9846878
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mammalian numb proteins promote Notch1 receptor ubiquitination and degradation of the Notch1 intracellular domain.
    McGill MA; McGlade CJ
    J Biol Chem; 2003 Jun; 278(25):23196-203. PubMed ID: 12682059
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.