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2. Tel/PDGFRbeta induces stem cell differentiation via the Ras/ERK and STAT5 signaling pathways. Dobbin E; Graham C; Corrigan PM; Thomas KG; Freeburn RW; Wheadon H Exp Hematol; 2009 Jan; 37(1):111-121. PubMed ID: 19100521 [TBL] [Abstract][Full Text] [Related]
3. Fatal myeloproliferation, induced in mice by TEL/PDGFbetaR expression, depends on PDGFbetaR tyrosines 579/581. Tomasson MH; Sternberg DW; Williams IR; Carroll M; Cain D; Aster JC; Ilaria RL; Van Etten RA; Gilliland DG J Clin Invest; 2000 Feb; 105(4):423-32. PubMed ID: 10683371 [TBL] [Abstract][Full Text] [Related]
4. Evidence for a role of NF-kappaB in the survival of hematopoietic cells mediated by interleukin 3 and the oncogenic TEL/platelet-derived growth factor receptor beta fusion protein. Besançon F; Atfi A; Gespach C; Cayre YE; Bourgeade MF Proc Natl Acad Sci U S A; 1998 Jul; 95(14):8081-6. PubMed ID: 9653143 [TBL] [Abstract][Full Text] [Related]
6. Rabaptin-5 is a novel fusion partner to platelet-derived growth factor beta receptor in chronic myelomonocytic leukemia. Magnusson MK; Meade KE; Brown KE; Arthur DC; Krueger LA; Barrett AJ; Dunbar CE Blood; 2001 Oct; 98(8):2518-25. PubMed ID: 11588050 [TBL] [Abstract][Full Text] [Related]
7. Translocation (12;22) (p13;q11) in myeloproliferative disorders results in fusion of the ETS-like TEL gene on 12p13 to the MN1 gene on 22q11. Buijs A; Sherr S; van Baal S; van Bezouw S; van der Plas D; Geurts van Kessel A; Riegman P; Lekanne Deprez R; Zwarthoff E; Hagemeijer A Oncogene; 1995 Apr; 10(8):1511-9. PubMed ID: 7731705 [TBL] [Abstract][Full Text] [Related]
8. Lhx2 expression in hematopoietic progenitor/stem cells in vivo causes a chronic myeloproliferative disorder and altered globin expression. Richter K; Pinto do O P; Hägglund AC; Wahlin A; Carlsson L Haematologica; 2003 Dec; 88(12):1336-47. PubMed ID: 14687986 [TBL] [Abstract][Full Text] [Related]
9. Sensitivity to imatinib but low frequency of the TEL/PDGFRbeta fusion protein in chronic myelomonocytic leukemia. Gunby RH; Cazzaniga G; Tassi E; Le Coutre P; Pogliani E; Specchia G; Biondi A; Gambacorti-Passerini C Haematologica; 2003 Apr; 88(4):408-15. PubMed ID: 12681968 [TBL] [Abstract][Full Text] [Related]
10. The TEL/platelet-derived growth factor beta receptor (PDGF beta R) fusion in chronic myelomonocytic leukemia is a transforming protein that self-associates and activates PDGF beta R kinase-dependent signaling pathways. Carroll M; Tomasson MH; Barker GF; Golub TR; Gilliland DG Proc Natl Acad Sci U S A; 1996 Dec; 93(25):14845-50. PubMed ID: 8962143 [TBL] [Abstract][Full Text] [Related]
11. Fusion of PDGF receptor beta to a novel ets-like gene, tel, in chronic myelomonocytic leukemia with t(5;12) chromosomal translocation. Golub TR; Barker GF; Lovett M; Gilliland DG Cell; 1994 Apr; 77(2):307-16. PubMed ID: 8168137 [TBL] [Abstract][Full Text] [Related]
12. Transgenic mice expressing Tel-FLT3, a constitutively activated form of FLT3, develop myeloproliferative disease. Baldwin BR; Li L; Tse KF; Small S; Collector M; Whartenby KA; Sharkis SJ; Racke F; Huso D; Small D Leukemia; 2007 Apr; 21(4):764-71. PubMed ID: 17268528 [TBL] [Abstract][Full Text] [Related]
13. Signal transduction and transforming properties of the TEL-TRKC fusions associated with t(12;15)(p13;q25) in congenital fibrosarcoma and acute myelogenous leukemia. Liu Q; Schwaller J; Kutok J; Cain D; Aster JC; Williams IR; Gilliland DG EMBO J; 2000 Apr; 19(8):1827-38. PubMed ID: 10775267 [TBL] [Abstract][Full Text] [Related]
14. MPLW515L is a novel somatic activating mutation in myelofibrosis with myeloid metaplasia. Pikman Y; Lee BH; Mercher T; McDowell E; Ebert BL; Gozo M; Cuker A; Wernig G; Moore S; Galinsky I; DeAngelo DJ; Clark JJ; Lee SJ; Golub TR; Wadleigh M; Gilliland DG; Levine RL PLoS Med; 2006 Jul; 3(7):e270. PubMed ID: 16834459 [TBL] [Abstract][Full Text] [Related]
15. The TEL/ETV6 gene is required specifically for hematopoiesis in the bone marrow. Wang LC; Swat W; Fujiwara Y; Davidson L; Visvader J; Kuo F; Alt FW; Gilliland DG; Golub TR; Orkin SH Genes Dev; 1998 Aug; 12(15):2392-402. PubMed ID: 9694803 [TBL] [Abstract][Full Text] [Related]
16. Response to imatinib mesylate in patients with chronic myeloproliferative diseases with rearrangements of the platelet-derived growth factor receptor beta. Apperley JF; Gardembas M; Melo JV; Russell-Jones R; Bain BJ; Baxter EJ; Chase A; Chessells JM; Colombat M; Dearden CE; Dimitrijevic S; Mahon FX; Marin D; Nikolova Z; Olavarria E; Silberman S; Schultheis B; Cross NC; Goldman JM N Engl J Med; 2002 Aug; 347(7):481-7. PubMed ID: 12181402 [TBL] [Abstract][Full Text] [Related]
17. Leukemogenic Ptpn11 causes fatal myeloproliferative disorder via cell-autonomous effects on multiple stages of hematopoiesis. Chan G; Kalaitzidis D; Usenko T; Kutok JL; Yang W; Mohi MG; Neel BG Blood; 2009 Apr; 113(18):4414-24. PubMed ID: 19179468 [TBL] [Abstract][Full Text] [Related]
18. Stem cell expression of the AML1/ETO fusion protein induces a myeloproliferative disorder in mice. Fenske TS; Pengue G; Mathews V; Hanson PT; Hamm SE; Riaz N; Graubert TA Proc Natl Acad Sci U S A; 2004 Oct; 101(42):15184-9. PubMed ID: 15477599 [TBL] [Abstract][Full Text] [Related]
19. Multiple oligomerization domains of KANK1-PDGFRβ are required for JAK2-independent hematopoietic cell proliferation and signaling via STAT5 and ERK. Medves S; Noël LA; Montano-Almendras CP; Albu RI; Schoemans H; Constantinescu SN; Demoulin JB Haematologica; 2011 Oct; 96(10):1406-14. PubMed ID: 21685469 [TBL] [Abstract][Full Text] [Related]
20. The Tel-Abl (ETV6-Abl) tyrosine kinase, product of complex (9;12) translocations in human leukemia, induces distinct myeloproliferative disease in mice. Million RP; Aster J; Gilliland DG; Van Etten RA Blood; 2002 Jun; 99(12):4568-77. PubMed ID: 12036890 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]