BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

304 related articles for article (PubMed ID: 10557352)

  • 1. Selective serotonin reuptake inhibitors directly alter activity of neurosteroidogenic enzymes.
    Griffin LD; Mellon SH
    Proc Natl Acad Sci U S A; 1999 Nov; 96(23):13512-7. PubMed ID: 10557352
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Kinetics of allopregnanolone formation catalyzed by human 3 alpha-hydroxysteroid dehydrogenase type III (AKR1C2).
    Trauger JW; Jiang A; Stearns BA; LoGrasso PV
    Biochemistry; 2002 Nov; 41(45):13451-9. PubMed ID: 12416991
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Fluoxetine elevates allopregnanolone in female rat brain but inhibits a steroid microsomal dehydrogenase rather than activating an aldo-keto reductase.
    Fry JP; Li KY; Devall AJ; Cockcroft S; Honour JW; Lovick TA
    Br J Pharmacol; 2014 Dec; 171(24):5870-80. PubMed ID: 25161074
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Human 3alpha-hydroxysteroid dehydrogenase isoforms (AKR1C1-AKR1C4) of the aldo-keto reductase superfamily: functional plasticity and tissue distribution reveals roles in the inactivation and formation of male and female sex hormones.
    Penning TM; Burczynski ME; Jez JM; Hung CF; Lin HK; Ma H; Moore M; Palackal N; Ratnam K
    Biochem J; 2000 Oct; 351(Pt 1):67-77. PubMed ID: 10998348
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Expression and characterization of recombinant type 2 3 alpha-hydroxysteroid dehydrogenase (HSD) from human prostate: demonstration of bifunctional 3 alpha/17 beta-HSD activity and cellular distribution.
    Lin HK; Jez JM; Schlegel BP; Peehl DM; Pachter JA; Penning TM
    Mol Endocrinol; 1997 Dec; 11(13):1971-84. PubMed ID: 9415401
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structure-function aspects and inhibitor design of type 5 17beta-hydroxysteroid dehydrogenase (AKR1C3).
    Penning TM; Burczynski ME; Jez JM; Lin HK; Ma H; Moore M; Ratnam K; Palackal N
    Mol Cell Endocrinol; 2001 Jan; 171(1-2):137-49. PubMed ID: 11165022
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Characterization of brain neurons that express enzymes mediating neurosteroid biosynthesis.
    Agís-Balboa RC; Pinna G; Zhubi A; Maloku E; Veldic M; Costa E; Guidotti A
    Proc Natl Acad Sci U S A; 2006 Sep; 103(39):14602-7. PubMed ID: 16984997
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Androgen formation and metabolism in the pulmonary epithelial cell line A549: expression of 17beta-hydroxysteroid dehydrogenase type 5 and 3alpha-hydroxysteroid dehydrogenase type 3.
    Provost PR; Blomquist CH; Godin C; Huang XF; Flamand N; Luu-The V; Nadeau D; Tremblay Y
    Endocrinology; 2000 Aug; 141(8):2786-94. PubMed ID: 10919264
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The socially-isolated mouse: a model to study the putative role of allopregnanolone and 5alpha-dihydroprogesterone in psychiatric disorders.
    Guidotti A; Dong E; Matsumoto K; Pinna G; Rasmusson AM; Costa E
    Brain Res Brain Res Rev; 2001 Nov; 37(1-3):110-5. PubMed ID: 11744079
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Expression levels of mRNA for neurosteroidogenic enzymes 17β-HSD, 5α-reductase, 3α-HSD and cytochrome P450 aromatase in the fetal wild type and SF-1 knockout mouse brain.
    Spanic T; Fabjan T; Majdic G
    Endocr Res; 2015; 40(1):44-8. PubMed ID: 25111584
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Neurosteroid biosynthesis regulates sexually dimorphic fear and aggressive behavior in mice.
    Pinna G; Agis-Balboa RC; Pibiri F; Nelson M; Guidotti A; Costa E
    Neurochem Res; 2008 Oct; 33(10):1990-2007. PubMed ID: 18473173
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Biosynthesis of the neurosteroid 3 alpha-hydroxy-4-pregnen-20-one (3 alpha hp), a specific inhibitor of FSH release.
    Griffin LD; Mellon SH
    Endocrinology; 2001 Nov; 142(11):4617-22. PubMed ID: 11606426
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Activity and expression of progesterone metabolizing 5alpha-reductase, 20alpha-hydroxysteroid oxidoreductase and 3alpha(beta)-hydroxysteroid oxidoreductases in tumorigenic (MCF-7, MDA-MB-231, T-47D) and nontumorigenic (MCF-10A) human breast cancer cells.
    Wiebe JP; Lewis MJ
    BMC Cancer; 2003 Mar; 3():9. PubMed ID: 12659654
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Isolation and characterization of a cDNA encoding mouse 3alpha-hydroxysteroid dehydrogenase: an androgen-inactivating enzyme selectively expressed in female tissues.
    Bellemare V; Labrie F; Luu-The V
    J Steroid Biochem Mol Biol; 2006 Jan; 98(1):18-24. PubMed ID: 16191478
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Identification of the oxidative 3alpha-hydroxysteroid dehydrogenase activity of rat Leydig cells as type II retinol dehydrogenase.
    Hardy DO; Ge RS; Catterall JF; Hou YT; Penning TM; Hardy MP
    Endocrinology; 2000 May; 141(5):1608-17. PubMed ID: 10803568
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Regional distribution of cytosolic and particulate 5alpha-dihydroprogesterone 3alpha-hydroxysteroid oxidoreductases in female rat brain.
    Li X; Bertics PJ; Karavolas HJ
    J Steroid Biochem Mol Biol; 1997 Mar; 60(5-6):311-8. PubMed ID: 9219922
    [TBL] [Abstract][Full Text] [Related]  

  • 17. In a mouse model relevant for post-traumatic stress disorder, selective brain steroidogenic stimulants (SBSS) improve behavioral deficits by normalizing allopregnanolone biosynthesis.
    Pinna G
    Behav Pharmacol; 2010 Sep; 21(5-6):438-50. PubMed ID: 20716970
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Androgen inactivation and steroid-converting enzyme expression in abdominal adipose tissue in men.
    Blouin K; Richard C; Brochu G; Hould FS; Lebel S; Marceau S; Biron S; Luu-The V; Tchernof A
    J Endocrinol; 2006 Dec; 191(3):637-49. PubMed ID: 17170221
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Characterization of the 5alpha-reductase-3alpha-hydroxysteroid dehydrogenase complex in the human brain.
    Steckelbroeck S; Watzka M; Reichelt R; Hans VH; Stoffel-Wagner B; Heidrich DD; Schramm J; Bidlingmaier F; Klingmüller D
    J Clin Endocrinol Metab; 2001 Mar; 86(3):1324-31. PubMed ID: 11238528
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Conversion of mammalian 3alpha-hydroxysteroid dehydrogenase to 20alpha-hydroxysteroid dehydrogenase using loop chimeras: changing specificity from androgens to progestins.
    Ma H; Penning TM
    Proc Natl Acad Sci U S A; 1999 Sep; 96(20):11161-6. PubMed ID: 10500147
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.