157 related articles for article (PubMed ID: 10561307)
21. Preclinical development of eniluracil: enhancing the therapeutic index and dosing convenience of 5-fluorouracil.
Paff MT; Baccanari DP; Davis ST; Cao S; Tansik RL; Rustum YM; Spector T
Invest New Drugs; 2000 Nov; 18(4):365-71. PubMed ID: 11081572
[TBL] [Abstract][Full Text] [Related]
22. Dihydropyrimidine dehydrogenase activity during long-term adjuvant treatment with oral uracil and tegafur for colorectal cancer.
Sadahiro S; Suzuki T; Maeda Y; Ishikawa K; Tanaka Y; Yasuda S; Kamijo A; Makuuchi H; Murayama C
Chemotherapy; 2007; 53(6):442-5. PubMed ID: 17952005
[TBL] [Abstract][Full Text] [Related]
23. Clinical development of eniluracil/fluorouracil: an oral treatment for patients with solid tumors.
Levin J; Hohneker J
Invest New Drugs; 2000 Nov; 18(4):383-90. PubMed ID: 11081574
[TBL] [Abstract][Full Text] [Related]
24. The uracil breath test in the assessment of dihydropyrimidine dehydrogenase activity: pharmacokinetic relationship between expired 13CO2 and plasma [2-13C]dihydrouracil.
Mattison LK; Fourie J; Hirao Y; Koga T; Desmond RA; King JR; Shimizu T; Diasio RB
Clin Cancer Res; 2006 Jan; 12(2):549-55. PubMed ID: 16428499
[TBL] [Abstract][Full Text] [Related]
25. A Phase I trial of preoperative eniluracil plus 5-fluorouracil and radiation for locally advanced or unresectable adenocarcinoma of the rectum and colon.
Czito BG; Hong TJ; Cohen DP; Tyler DS; Lee CG; Anscher MS; Ludwig KA; Seigler HF; Mantyh C; Morse MA; Lockhart AC; Petros WP; Honeycutt W; Spector NL; Ertel PJ; Mangum SG; Hurwitz HI
Int J Radiat Oncol Biol Phys; 2004 Mar; 58(3):779-85. PubMed ID: 14967434
[TBL] [Abstract][Full Text] [Related]
26. Dihydropyrimidine dehydrogenase: a tumoral target for fluorouracil modulation.
Fischel JL; Etienne MC; Spector T; Formento P; Renée N; Milano G
Clin Cancer Res; 1995 Sep; 1(9):991-6. PubMed ID: 9816071
[TBL] [Abstract][Full Text] [Related]
27. Thymidylate synthase and dihydropyrimidine dehydrogenase mRNA expression after administration of 5-fluorouracil to patients with colorectal cancer.
Mauritz R; van Groeningen CJ; Smid K; Jansen G; Pinedo HM; Peters GJ
Int J Cancer; 2007 Jun; 120(12):2609-12. PubMed ID: 17330233
[TBL] [Abstract][Full Text] [Related]
28. Tumor dihydropyrimidine dehydrogenase expression is a useful marker in adjuvant therapy with oral fluoropyrimidines after curative resection of colorectal cancer.
Tsuji T; Sawai T; Takeshita H; Nakagoe T; Hidaka S; Yamaguchi H; Yasutake T; Nagayasu T; Tagawa Y
Cancer Chemother Pharmacol; 2004 Dec; 54(6):531-6. PubMed ID: 15309506
[TBL] [Abstract][Full Text] [Related]
29. A study to evaluate the pharmacokinetics of oral 5-fluorouracil and eniluracil after concurrent administration to patients with refractory solid tumours and varying degrees of renal impairment (FUMA1005).
O'Donnell A; Punt CJ; Judson I; Van Maanen L; Suttle AB; Ertel P; Beale P
Cancer Chemother Pharmacol; 2003 Jan; 51(1):58-66. PubMed ID: 12497207
[TBL] [Abstract][Full Text] [Related]
30. Correlation between dihydropyrimidine dehydrogenase activity in peripheral mononuclear cells and systemic clearance of fluorouracil in cancer patients.
Fleming RA; Milano G; Thyss A; Etienne MC; Renée N; Schneider M; Demard F
Cancer Res; 1992 May; 52(10):2899-902. PubMed ID: 1581906
[TBL] [Abstract][Full Text] [Related]
31. The effect of sorivudine on dihydropyrimidine dehydrogenase activity in patients with acute herpes zoster.
Yan J; Tyring SK; McCrary MM; Lee PC; Haworth S; Raymond R; Olsen SJ; Diasio RB
Clin Pharmacol Ther; 1997 May; 61(5):563-73. PubMed ID: 9164418
[TBL] [Abstract][Full Text] [Related]
32. Combination of dihydropyrimidine dehydrogenase and thymidylate synthase gene expressions in primary tumors as predictive parameters for the efficacy of fluoropyrimidine-based chemotherapy for metastatic colorectal cancer.
Ichikawa W; Uetake H; Shirota Y; Yamada H; Nishi N; Nihei Z; Sugihara K; Hirayama R
Clin Cancer Res; 2003 Feb; 9(2):786-91. PubMed ID: 12576451
[TBL] [Abstract][Full Text] [Related]
33. Augmentation of the antitumor activity of capecitabine by a tumor selective dihydropyrimidine dehydrogenase inhibitor, RO0094889.
Endo M; Miwa M; Eda H; Ura M; Tanimura H; Ishikawa T; Miyazaki-Nose T; Hattori K; Shimma N; Yamada-Okabe H; Ishitsuka H
Int J Cancer; 2003 Sep; 106(5):799-805. PubMed ID: 12866042
[TBL] [Abstract][Full Text] [Related]
34. Evaluation of an oral uracil loading test to identify DPD-deficient patients using a limited sampling strategy.
van Staveren MC; van Kuilenburg AB; Guchelaar HJ; Meijer J; Punt CJ; de Jong RS; Gelderblom H; Maring JG
Br J Clin Pharmacol; 2016 Mar; 81(3):553-61. PubMed ID: 26551538
[TBL] [Abstract][Full Text] [Related]
35. A phase I study of eniluracil/5-FU in combination with radiation therapy for potentially resectable and/or unresectable cancer of the pancreas and distal biliary tract.
Czito BG; Hong TJ; Cohen DP; Petros WP; Tyler DS; Pappas TN; Yu D; Lee CG; Lockhart AC; Morse MA; Fernando N; Hurwitz HI
Cancer Invest; 2006 Feb; 24(1):9-17. PubMed ID: 16466986
[TBL] [Abstract][Full Text] [Related]
36. [Tumoral dihydropyrimidine dehydrogenase expression and efficacy of 5-fluorouracil plus leucovorin plus UFT therapy in patients with colorectal cancer].
Ishida H; Ohsawa T; Nakada H; Yokoyama M; Inokuma S; Shirakawa K; Yamada H; Hashimoto D
Gan To Kagaku Ryoho; 2004 Jun; 31(6):883-7. PubMed ID: 15222105
[TBL] [Abstract][Full Text] [Related]
37. Intratumoral dihydropyrimidine dehydrogenase messenger RNA level reflects tumor progression in human colorectal cancer.
Shirota Y; Ichikawa W; Uetake H; Yamada H; Nihei Z; Sugihara K
Ann Surg Oncol; 2002 Jul; 9(6):599-603. PubMed ID: 12095978
[TBL] [Abstract][Full Text] [Related]
38. Colorectal tumors responding to 5-fluorouracil have low gene expression levels of dihydropyrimidine dehydrogenase, thymidylate synthase, and thymidine phosphorylase.
Salonga D; Danenberg KD; Johnson M; Metzger R; Groshen S; Tsao-Wei DD; Lenz HJ; Leichman CG; Leichman L; Diasio RB; Danenberg PV
Clin Cancer Res; 2000 Apr; 6(4):1322-7. PubMed ID: 10778957
[TBL] [Abstract][Full Text] [Related]
39. Characterization of dihydropyrimidine dehydrogenase in human colorectal tumours.
McLeod HL; Sludden J; Murray GI; Keenan RA; Davidson AI; Park K; Koruth M; Cassidy J
Br J Cancer; 1998; 77(3):461-5. PubMed ID: 9472644
[TBL] [Abstract][Full Text] [Related]
40. 5-Ethynyluracil (776C85): inactivation of dihydropyrimidine dehydrogenase in vivo.
Spector T; Harrington JA; Porter DJ
Biochem Pharmacol; 1993 Dec; 46(12):2243-8. PubMed ID: 8274158
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]