BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

210 related articles for article (PubMed ID: 10567369)

  • 1. The N-terminal ERK-binding site of MEK1 is required for efficient feedback phosphorylation by ERK2 in vitro and ERK activation in vivo.
    Xu Be; Wilsbacher JL; Collisson T; Cobb MH
    J Biol Chem; 1999 Nov; 274(48):34029-35. PubMed ID: 10567369
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mitogen-activated protein kinase feedback phosphorylation regulates MEK1 complex formation and activation during cellular adhesion.
    Eblen ST; Slack-Davis JK; Tarcsafalvi A; Parsons JT; Weber MJ; Catling AD
    Mol Cell Biol; 2004 Mar; 24(6):2308-17. PubMed ID: 14993270
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Rac-PAK signaling stimulates extracellular signal-regulated kinase (ERK) activation by regulating formation of MEK1-ERK complexes.
    Eblen ST; Slack JK; Weber MJ; Catling AD
    Mol Cell Biol; 2002 Sep; 22(17):6023-33. PubMed ID: 12167697
    [TBL] [Abstract][Full Text] [Related]  

  • 4. PAK1 primes MEK1 for phosphorylation by Raf-1 kinase during cross-cascade activation of the ERK pathway.
    Coles LC; Shaw PE
    Oncogene; 2002 Mar; 21(14):2236-44. PubMed ID: 11948406
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The MEK1 proline-rich insert is required for efficient activation of the mitogen-activated protein kinases ERK1 and ERK2 in mammalian cells.
    Dang A; Frost JA; Cobb MH
    J Biol Chem; 1998 Jul; 273(31):19909-13. PubMed ID: 9677429
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Hydrophobic as well as charged residues in both MEK1 and ERK2 are important for their proper docking.
    Xu Be ; Stippec S; Robinson FL; Cobb MH
    J Biol Chem; 2001 Jul; 276(28):26509-15. PubMed ID: 11352917
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Docking sites on mitogen-activated protein kinase (MAPK) kinases, MAPK phosphatases and the Elk-1 transcription factor compete for MAPK binding and are crucial for enzymic activity.
    Bardwell AJ; Abdollahi M; Bardwell L
    Biochem J; 2003 Mar; 370(Pt 3):1077-85. PubMed ID: 12529172
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Identification of novel point mutations in ERK2 that selectively disrupt binding to MEK1.
    Robinson FL; Whitehurst AW; Raman M; Cobb MH
    J Biol Chem; 2002 Apr; 277(17):14844-52. PubMed ID: 11823456
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A bipartite mechanism for ERK2 recognition by its cognate regulators and substrates.
    Zhang J; Zhou B; Zheng CF; Zhang ZY
    J Biol Chem; 2003 Aug; 278(32):29901-12. PubMed ID: 12754209
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Phosphorylation of 338SSYY341 regulates specific interaction between Raf-1 and MEK1.
    Xiang X; Zang M; Waelde CA; Wen R; Luo Z
    J Biol Chem; 2002 Nov; 277(47):44996-5003. PubMed ID: 12244094
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Kinase suppressor of ras is necessary for tumor necrosis factor alpha activation of extracellular signal-regulated kinase/mitogen-activated protein kinase in intestinal epithelial cells.
    Yan F; Polk DB
    Cancer Res; 2001 Feb; 61(3):963-9. PubMed ID: 11221891
    [TBL] [Abstract][Full Text] [Related]  

  • 12. MEK1 is required for PDGF-induced ERK activation and DNA synthesis in tracheal myocytes.
    Karpova AY; Abe MK; Li J; Liu PT; Rhee JM; Kuo WL; Hershenson MB
    Am J Physiol; 1997 Mar; 272(3 Pt 1):L558-65. PubMed ID: 9124614
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Cross-cascade activation of ERKs and ternary complex factors by Rho family proteins.
    Frost JA; Steen H; Shapiro P; Lewis T; Ahn N; Shaw PE; Cobb MH
    EMBO J; 1997 Nov; 16(21):6426-38. PubMed ID: 9351825
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Adhesion stimulates direct PAK1/ERK2 association and leads to ERK-dependent PAK1 Thr212 phosphorylation.
    Sundberg-Smith LJ; Doherty JT; Mack CP; Taylor JM
    J Biol Chem; 2005 Jan; 280(3):2055-64. PubMed ID: 15542607
    [TBL] [Abstract][Full Text] [Related]  

  • 15. PAK1 phosphorylation of MEK1 regulates fibronectin-stimulated MAPK activation.
    Slack-Davis JK; Eblen ST; Zecevic M; Boerner SA; Tarcsafalvi A; Diaz HB; Marshall MS; Weber MJ; Parsons JT; Catling AD
    J Cell Biol; 2003 Jul; 162(2):281-91. PubMed ID: 12876277
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Novel membrane-targeted ERK1 and ERK2 chimeras which act as dominant negative, isotype-specific mitogen-activated protein kinase inhibitors of Ras-Raf-mediated transcriptional activation of c-fos in NIH 3T3 cells.
    Hochholdinger F; Baier G; Nogalo A; Bauer B; Grunicke HH; Uberall F
    Mol Cell Biol; 1999 Dec; 19(12):8052-65. PubMed ID: 10567531
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Expression of human cystatin A by keratinocytes is positively regulated via the Ras/MEKK1/MKK7/JNK signal transduction pathway but negatively regulated via the Ras/Raf-1/MEK1/ERK pathway.
    Takahashi H; Honma M; Ishida-Yamamoto A; Namikawa K; Kiyama H; Iizuka H
    J Biol Chem; 2001 Sep; 276(39):36632-8. PubMed ID: 11451947
    [TBL] [Abstract][Full Text] [Related]  

  • 18. c-Raf/MEK/ERK pathway controls protein kinase C-mediated p70S6K activation in adult cardiac muscle cells.
    Iijima Y; Laser M; Shiraishi H; Willey CD; Sundaravadivel B; Xu L; McDermott PJ; Kuppuswamy D
    J Biol Chem; 2002 Jun; 277(25):23065-75. PubMed ID: 11940578
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Differential abilities of the Raf family of protein kinases to abrogate cytokine dependency and prevent apoptosis in murine hematopoietic cells by a MEK1-dependent mechanism.
    Hoyle PE; Moye PW; Steelman LS; Blalock WL; Franklin RA; Pearce M; Cherwinski H; Bosch E; McMahon M; McCubrey JA
    Leukemia; 2000 Apr; 14(4):642-56. PubMed ID: 10764150
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A docking site in MKK4 mediates high affinity binding to JNK MAPKs and competes with similar docking sites in JNK substrates.
    Ho DT; Bardwell AJ; Abdollahi M; Bardwell L
    J Biol Chem; 2003 Aug; 278(35):32662-72. PubMed ID: 12788955
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.