182 related articles for article (PubMed ID: 10570051)
1. Differential interaction of R-mexiletine with the local anesthetic receptor site on brain and heart sodium channel alpha-subunits.
Weiser T; Qu Y; Catterall WA; Scheuer T
Mol Pharmacol; 1999 Dec; 56(6):1238-44. PubMed ID: 10570051
[TBL] [Abstract][Full Text] [Related]
2. Molecular determinants of drug access to the receptor site for antiarrhythmic drugs in the cardiac Na+ channel.
Qu Y; Rogers J; Tanada T; Scheuer T; Catterall WA
Proc Natl Acad Sci U S A; 1995 Dec; 92(25):11839-43. PubMed ID: 8524860
[TBL] [Abstract][Full Text] [Related]
3. Mexiletine block of disease-associated mutations in S6 segments of the human skeletal muscle Na(+) channel.
Takahashi MP; Cannon SC
J Physiol; 2001 Dec; 537(Pt 3):701-14. PubMed ID: 11744749
[TBL] [Abstract][Full Text] [Related]
4. Unexpected mexiletine responses of a mutant cardiac Na+ channel implicate the selectivity filter as a structural determinant of antiarrhythmic drug access.
Sasaki K; Makita N; Sunami A; Sakurada H; Shirai N; Yokoi H; Kimura A; Tohse N; Hiraoka M; Kitabatake A
Mol Pharmacol; 2004 Aug; 66(2):330-6. PubMed ID: 15266024
[TBL] [Abstract][Full Text] [Related]
5. Molecular basis for exaggerated sensitivity to mexiletine in the cardiac isoform of the fast Na channel.
Kawagoe H; Yamaoka K; Kinoshita E; Fujimoto Y; Maejima H; Yuki T; Seyama I
FEBS Lett; 2002 Feb; 513(2-3):235-41. PubMed ID: 11904157
[TBL] [Abstract][Full Text] [Related]
6. Mexiletine Block of Voltage-Gated Sodium Channels: Isoform- and State-Dependent Drug-Pore Interactions.
Nakagawa H; Munakata T; Sunami A
Mol Pharmacol; 2019 Mar; 95(3):236-244. PubMed ID: 30593458
[TBL] [Abstract][Full Text] [Related]
7. Mexiletine block of wild-type and inactivation-deficient human skeletal muscle hNav1.4 Na+ channels.
Wang GK; Russell C; Wang SY
J Physiol; 2004 Feb; 554(Pt 3):621-33. PubMed ID: 14608007
[TBL] [Abstract][Full Text] [Related]
8. Block of human heart hH1 sodium channels by the enantiomers of bupivacaine.
Nau C; Wang SY; Strichartz GR; Wang GK
Anesthesiology; 2000 Oct; 93(4):1022-33. PubMed ID: 11020758
[TBL] [Abstract][Full Text] [Related]
9. Common molecular determinants of local anesthetic, antiarrhythmic, and anticonvulsant block of voltage-gated Na+ channels.
Ragsdale DS; McPhee JC; Scheuer T; Catterall WA
Proc Natl Acad Sci U S A; 1996 Aug; 93(17):9270-5. PubMed ID: 8799190
[TBL] [Abstract][Full Text] [Related]
10. Molecular determinants of state-dependent block of voltage-gated sodium channels by pilsicainide.
Desaphy JF; Dipalma A; Costanza T; Bruno C; Lentini G; Franchini C; George A; Conte Camerino D
Br J Pharmacol; 2010 Jul; 160(6):1521-33. PubMed ID: 20590641
[TBL] [Abstract][Full Text] [Related]
11. Lysine point mutations in Na+ channel D4-S6 reduce inactivated channel block by local anesthetics.
Wright SN; Wang SY; Wang GK
Mol Pharmacol; 1998 Oct; 54(4):733-9. PubMed ID: 9765517
[TBL] [Abstract][Full Text] [Related]
12. Inhibition of frog skeletal muscle sodium channels by newly synthesized chiral derivatives of mexiletine and tocainide.
De Luca A; Natuzzi F; Falcone G; Duranti A; Lentini G; Franchini C; Tortorella V; Camerino DC
Naunyn Schmiedebergs Arch Pharmacol; 1997 Dec; 356(6):777-87. PubMed ID: 9453464
[TBL] [Abstract][Full Text] [Related]
13. Electrophysiologic effects of an antiarrhythmic agent, bidisomide, on sodium current in isolated rat ventricular myocytes: comparison with mexiletine and disopyramide.
Homma N; Tsujimoto G; Hashimoto K
Jpn J Pharmacol; 2001 May; 86(1):23-31. PubMed ID: 11430469
[TBL] [Abstract][Full Text] [Related]
14. A combination of inactivated sodium channel blockers causes competitive interaction on dV/dtmax of single ventricular myocytes.
Kamiya K; Kodama I; Toyama J
Cardiovasc Res; 1991 Jun; 25(6):516-22. PubMed ID: 1653644
[TBL] [Abstract][Full Text] [Related]
15. Preferred mexiletine block of human sodium channels with IVS4 mutations and its pH-dependence.
Mohammadi B; Jurkat-Rott K; Alekov A; Dengler R; Bufler J; Lehmann-Horn F
Pharmacogenet Genomics; 2005 Apr; 15(4):235-44. PubMed ID: 15864116
[TBL] [Abstract][Full Text] [Related]
16. Prenylamine block of Nav1.5 channel is mediated via a receptor distinct from that of local anesthetics.
Mujtaba MG; Wang SY; Wang GK
Mol Pharmacol; 2002 Aug; 62(2):415-22. PubMed ID: 12130695
[TBL] [Abstract][Full Text] [Related]
17. Combined application of class I antiarrhythmic drugs causes "additive", "reductive", or "synergistic" sodium channel block in cardiac muscles.
Kawamura T; Kodama I; Toyama J; Hayashi H; Saito H; Yamada K
Cardiovasc Res; 1990 Nov; 24(11):925-31. PubMed ID: 2176934
[TBL] [Abstract][Full Text] [Related]
18. Different effects of mexiletine on two mutant sodium channels causing paramyotonia congenita and hyperkalemic periodic paralysis.
Weckbecker K; Würz A; Mohammadi B; Mansuroglu T; George AL; Lerche H; Dengler R; Lehmann-Horn F; Mitrovic N
Neuromuscul Disord; 2000 Jan; 10(1):31-9. PubMed ID: 10677861
[TBL] [Abstract][Full Text] [Related]
19. Regulation of sodium channel gene expression by class I antiarrhythmic drugs and n - 3 polyunsaturated fatty acids in cultured neonatal rat cardiac myocytes.
Kang JX; Li Y; Leaf A
Proc Natl Acad Sci U S A; 1997 Mar; 94(6):2724-8. PubMed ID: 9122264
[TBL] [Abstract][Full Text] [Related]
20. A model analysis for competitive binding of mexiletine and aprindine to the cardiac sodium channel.
Kamiya K; Toyama J; Honjo H; Kodama I
Pharmacology; 1992; 44(5):260-8. PubMed ID: 1320276
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
