BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

135 related articles for article (PubMed ID: 10571162)

  • 1. Synthesis and antitumor activity of water-soluble duocarmycin B1 prodrugs.
    Asai A; Nagamura S; Kobayashi E; Gomi K; Saito H
    Bioorg Med Chem Lett; 1999 Oct; 9(20):2995-8. PubMed ID: 10571162
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis and antitumor activity of duocarmycin derivatives.
    Nagamura S; Kanda Y; Kobayashi E; Gomi K; Saito H
    Chem Pharm Bull (Tokyo); 1995 Sep; 43(9):1530-5. PubMed ID: 7586077
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis and antitumor activity of duocarmycin derivatives: A-ring pyrrole compounds bearing cinnamoyl groups.
    Nagamura S; Asai A; Amishiro N; Kobayashi E; Gomi K; Saito H
    J Med Chem; 1997 Mar; 40(6):972-9. PubMed ID: 9083487
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis and antitumor activity of duocarmycin derivatives: modification of segment A of duocarmycin B2.
    Nagamura S; Asai A; Kanda Y; Kobayashi E; Gomi K; Saito H
    Chem Pharm Bull (Tokyo); 1996 Sep; 44(9):1723-30. PubMed ID: 8855367
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis and antitumor activity of duocarmycin derivatives: modification at C-8 position of A-ring pyrrole compounds bearing the simplified DNA-binding groups.
    Amishiro N; Nagamura S; Murakata C; Okamoto A; Kobayashi E; Asada M; Gomi K; Tamaoki T; Okabe M; Yamaguchi N; Yamaguchi K; Saito H
    Bioorg Med Chem; 2000 Feb; 8(2):381-91. PubMed ID: 10722161
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis and antitumor activity of duocarmycin derivatives: A-ring pyrrole compounds bearing beta-(5',6',7'-trimethoxy-2'-indolyl)acryloyl group.
    Amishiro N; Nagamura S; Kobayashi E; Okamoto A; Gomi K; Okabe M; Saito H
    Bioorg Med Chem; 2000 Jul; 8(7):1637-43. PubMed ID: 10976511
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Characteristics of antitumor activity of KW-2189, a novel water-soluble derivative of duocarmycin, against murine and human tumors.
    Kobayashi E; Okamoto A; Asada M; Okabe M; Nagamura S; Asai A; Saito H; Gomi K; Hirata T
    Cancer Res; 1994 May; 54(9):2404-10. PubMed ID: 8162588
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis and antitumor activity of duocarmycin derivatives: A-ring pyrrole analogues of duocarmycin B2.
    Nagamura S; Kobayashi E; Gomi K; Saito H
    Bioorg Med Chem; 1996 Aug; 4(8):1379-91. PubMed ID: 8879561
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Establishing the parabolic relationship between reactivity and activity for derivatives and analogues of the duocarmycin and CC-1065 alkylation subunits.
    Parrish JP; Hughes TV; Hwang I; Boger DL
    J Am Chem Soc; 2004 Jan; 126(1):80-1. PubMed ID: 14709069
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis and antitumor activity of CBI-bearing ester and carbamate prodrugs of CC-1065 analogue.
    Wang Y; Li L; Tian Z; Jiang W; Larrick JW
    Bioorg Med Chem; 2006 Dec; 14(23):7854-61. PubMed ID: 16908174
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Solid-Phase Synthesis of Duocarmycin Analogues and the Effect of C-Terminal Substitution on Biological Activity.
    Stephenson MJ; Howell LA; O'Connell MA; Fox KR; Adcock C; Kingston J; Sheldrake H; Pors K; Collingwood SP; Searcey M
    J Org Chem; 2015 Oct; 80(19):9454-67. PubMed ID: 26356089
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis and evaluation of water-soluble paclitaxel prodrugs.
    Feng X; Yuan YJ; Wu JC
    Bioorg Med Chem Lett; 2002 Nov; 12(22):3301-3. PubMed ID: 12392737
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis and antitumor activity of duocarmycin derivatives: modification of segment-A of A-ring pyrrole compounds.
    Amishiro N; Okamoto A; Murakata C; Tamaoki T; Okabe M; Saito H
    J Med Chem; 1999 Jul; 42(15):2946-60. PubMed ID: 10425104
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Duocarmycins--natures prodrugs?
    Searcey M
    Curr Pharm Des; 2002; 8(15):1375-89. PubMed ID: 12052214
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A novel, unusually efficacious duocarmycin carbamate prodrug that releases no residual byproduct.
    Wolfe AL; Duncan KK; Parelkar NK; Weir SJ; Vielhauer GA; Boger DL
    J Med Chem; 2012 Jun; 55(12):5878-86. PubMed ID: 22650244
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis of taxoids 5. Synthesis and evaluation of novel water-soluble prodrugs of a 3'-desphenyl-3'-cyclopropyl analogue of docetaxel.
    Yamaguchi T; Harada N; Ozaki K; Arakawa H; Oda K; Nakanishi N; Tsujihara K; Hashiyama T
    Bioorg Med Chem Lett; 1999 Jun; 9(12):1639-44. PubMed ID: 10397492
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Site specific covalent alkylation of DNA by antitumor antibiotics, duocarmycin A and kapurimycin A3.
    Sugiyama H; Lam CK; Hosoda M; Saito I
    Nucleic Acids Symp Ser; 1991; (25):75-6. PubMed ID: 1842103
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Studies on duocarmycin SA and its derivatives.
    Nagamura S; Asai A; Kobayashi E; Gomi K; Saito H
    Bioorg Med Chem; 1997 Mar; 5(3):623-30. PubMed ID: 9113339
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Interconversion and stability of duocarmycins, a new family of antitumor antibiotics: correlation to their cytotoxic and antimicrobial activities in vitro.
    Ichimura M; Ogawa T; Takahashi K; Mihara A; Takahashi I; Nakano H
    Oncol Res; 1993; 5(4-5):165-71. PubMed ID: 8305742
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Photoactivatable prodrugs of highly potent duocarmycin analogues for a selective cancer therapy.
    Tietze LF; Müller M; Duefert SC; Schmuck K; Schuberth I
    Chemistry; 2013 Jan; 19(5):1726-31. PubMed ID: 23225610
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.