BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

192 related articles for article (PubMed ID: 10571990)

  • 21. Structure and function of 2,3-dimethylmalate lyase, a PEP mutase/isocitrate lyase superfamily member.
    Narayanan B; Niu W; Joosten HJ; Li Z; Kuipers RK; Schaap PJ; Dunaway-Mariano D; Herzberg O
    J Mol Biol; 2009 Feb; 386(2):486-503. PubMed ID: 19133276
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Functional cloning and mutational analysis of the human cDNA for phosphoacetylglucosamine mutase: identification of the amino acid residues essential for the catalysis.
    Mio T; Yamada-Okabe T; Arisawa M; Yamada-Okabe H
    Biochim Biophys Acta; 2000 Jul; 1492(2-3):369-76. PubMed ID: 11004509
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Mutational, kinetic, and NMR studies of the roles of conserved glutamate residues and of lysine-39 in the mechanism of the MutT pyrophosphohydrolase.
    Harris TK; Wu G; Massiah MA; Mildvan AS
    Biochemistry; 2000 Feb; 39(7):1655-74. PubMed ID: 10677214
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Site-directed mutagenesis of UDP-galactopyranose mutase reveals a critical role for the active-site, conserved arginine residues.
    Chad JM; Sarathy KP; Gruber TD; Addala E; Kiessling LL; Sanders DA
    Biochemistry; 2007 Jun; 46(23):6723-32. PubMed ID: 17511471
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Tyr235 of human cytosolic phosphoenolpyruvate carboxykinase influences catalysis through an anion-quadrupole interaction with phosphoenolpyruvate carboxylate.
    Dharmarajan L; Case CL; Dunten P; Mukhopadhyay B
    FEBS J; 2008 Dec; 275(23):5810-9. PubMed ID: 19021757
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Mechanism-based inhibition of enzyme I of the Escherichia coli phosphotransferase system. Cysteine 502 is an essential residue.
    Garcia-Alles LF; Flükiger K; Hewel J; Gutknecht R; Siebold C; Schürch S; Erni B
    J Biol Chem; 2002 Mar; 277(9):6934-42. PubMed ID: 11741915
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Exhaustive mutagenesis of six secondary active-site residues in Escherichia coli chorismate mutase shows the importance of hydrophobic side chains and a helix N-capping position for stability and catalysis.
    Lassila JK; Keeffe JR; Kast P; Mayo SL
    Biochemistry; 2007 Jun; 46(23):6883-91. PubMed ID: 17506527
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Pyruvate site of pyruvate phosphate dikinase: crystal structure of the enzyme-phosphonopyruvate complex, and mutant analysis.
    Herzberg O; Chen CC; Liu S; Tempczyk A; Howard A; Wei M; Ye D; Dunaway-Mariano D
    Biochemistry; 2002 Jan; 41(3):780-7. PubMed ID: 11790099
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Investigation of metal ion binding in phosphonoacetaldehyde hydrolase identifies sequence markers for metal-activated enzymes of the HAD enzyme superfamily.
    Zhang G; Morais MC; Dai J; Zhang W; Dunaway-Mariano D; Allen KN
    Biochemistry; 2004 May; 43(17):4990-7. PubMed ID: 15109258
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Active site mutants of Escherichia coli dethiobiotin synthetase: effects of mutations on enzyme catalytic and structural properties.
    Yang G; Sandalova T; Lohman K; Lindqvist Y; Rendina AR
    Biochemistry; 1997 Apr; 36(16):4751-60. PubMed ID: 9125495
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Identification of the catalytic residues of AroA (Enolpyruvylshikimate 3-phosphate synthase) using partitioning analysis.
    Mizyed S; Wright JE; Byczynski B; Berti PJ
    Biochemistry; 2003 Jun; 42(23):6986-95. PubMed ID: 12795593
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Saccharomyces cerevisiae phosphoenolpyruvate carboxykinase: relevance of arginine 70 for catalysis.
    Cristina Ravanal M; Flores M; Pérez E; Aroca F; Cardemil E
    Biochimie; 2004 Jun; 86(6):357-62. PubMed ID: 15358051
    [TBL] [Abstract][Full Text] [Related]  

  • 33. A carboxylate oxygen of the substrate bridges the magnesium ions at the active site of enolase: structure of the yeast enzyme complexed with the equilibrium mixture of 2-phosphoglycerate and phosphoenolpyruvate at 1.8 A resolution.
    Larsen TM; Wedekind JE; Rayment I; Reed GH
    Biochemistry; 1996 Apr; 35(14):4349-58. PubMed ID: 8605183
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Site-directed mutagenesis of Escherichia coli acetylglutamate kinase and aspartokinase III probes the catalytic and substrate-binding mechanisms of these amino acid kinase family enzymes and allows three-dimensional modelling of aspartokinase.
    Marco-Marín C; Ramón-Maiques S; Tavárez S; Rubio V
    J Mol Biol; 2003 Nov; 334(3):459-76. PubMed ID: 14623187
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Backbone flexibility, conformational change, and catalysis in a phosphohexomutase from Pseudomonas aeruginosa.
    Schramm AM; Mehra-Chaudhary R; Furdui CM; Beamer LJ
    Biochemistry; 2008 Sep; 47(35):9154-62. PubMed ID: 18690721
    [TBL] [Abstract][Full Text] [Related]  

  • 36. 6-Pyruvoyl tetrahydropterin synthase, an enzyme with a novel type of active site involving both zinc binding and an intersubunit catalytic triad motif; site-directed mutagenesis of the proposed active center, characterization of the metal binding site and modelling of substrate binding.
    Bürgisser DM; Thöny B; Redweik U; Hess D; Heizmann CW; Huber R; Nar H
    J Mol Biol; 1995 Oct; 253(2):358-69. PubMed ID: 7563095
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Structure-based redesign of the catalytic/metal binding site of Cfr10I restriction endonuclease reveals importance of spatial rather than sequence conservation of active centre residues.
    Skirgaila R; Grazulis S; Bozic D; Huber R; Siksnys V
    J Mol Biol; 1998 Jun; 279(2):473-81. PubMed ID: 9642051
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Conformational cycling in beta-phosphoglucomutase catalysis: reorientation of the beta-D-glucose 1,6-(Bis)phosphate intermediate.
    Dai J; Wang L; Allen KN; Radstrom P; Dunaway-Mariano D
    Biochemistry; 2006 Jun; 45(25):7818-24. PubMed ID: 16784233
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Evolution of enzymatic activity in the enolase superfamily: structure of o-succinylbenzoate synthase from Escherichia coli in complex with Mg2+ and o-succinylbenzoate.
    Thompson TB; Garrett JB; Taylor EA; Meganathan R; Gerlt JA; Rayment I
    Biochemistry; 2000 Sep; 39(35):10662-76. PubMed ID: 10978150
    [TBL] [Abstract][Full Text] [Related]  

  • 40. On the multiple functional roles of the active site histidine in catalysis and allosteric regulation of Escherichia coli glucosamine 6-phosphate deaminase.
    Montero-Morán GM; Lara-González S; Alvarez-Añorve LI; Plumbridge JA; Calcagno ML
    Biochemistry; 2001 Aug; 40(34):10187-96. PubMed ID: 11513596
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 10.