These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

151 related articles for article (PubMed ID: 10579824)

  • 1. Asymmetric synthesis of 9-alkyl-2-benzyl-6,7-benzomorphans: characterization as novel sigma receptor ligands.
    Carroll FI; Bai X; Dehghani A; Mascarella SW; Williams W; Bowen WD
    J Med Chem; 1999 Nov; 42(22):4621-9. PubMed ID: 10579824
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis and in vitro and in vivo activity of (-)-(1R,5R,9R)- and (+)-(1S,5S,9S)-N-alkenyl-, -N-alkynyl-, and -N-cyanoalkyl-5, 9-dimethyl-2'-hydroxy-6,7-benzomorphan homologues.
    May EL; Jacobson AE; Mattson MV; Traynor JR; Woods JH; Harris LS; Bowman ER; Aceto MD
    J Med Chem; 2000 Dec; 43(26):5030-6. PubMed ID: 11150174
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis and sigma binding properties of 2'-substituted 5,9 alpha-dimethyl-6,7-benzomorphans.
    Danso-Danquah R; Bai X; Zhang X; Mascarella SW; Williams W; Sine B; Bowen WD; Carroll FI
    J Med Chem; 1995 Jul; 38(15):2978-85. PubMed ID: 7636860
    [TBL] [Abstract][Full Text] [Related]  

  • 4. (+)-cis-N-ethyleneamino-N-normetazocine derivatives. Novel and selective sigma ligands with antagonist properties.
    Ronsisvalle G; Marrazzo A; Prezzavento O; Pasquinucci L; Vittorio F; Pittalà V; Pappalardo MS; Cacciaguerra S; Spampinato S
    J Med Chem; 1998 May; 41(10):1574-80. PubMed ID: 9572883
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Rat liver and kidney contain high densities of sigma 1 and sigma 2 receptors: characterization by ligand binding and photoaffinity labeling.
    Hellewell SB; Bruce A; Feinstein G; Orringer J; Williams W; Bowen WD
    Eur J Pharmacol; 1994 Jun; 268(1):9-18. PubMed ID: 7925616
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis and receptor binding properties of fluoro- and iodo-substituted high affinity sigma receptor ligands: identification of potential PET and SPECT sigma receptor imaging agents.
    de Costa B; Radesca L; Dominguez C; Di Paolo L; Bowen WD
    J Med Chem; 1992 Jun; 35(12):2221-30. PubMed ID: 1319493
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Electrophilic gamma-lactone kappa-opioid receptor probes. Analogues of 2'-hydroxy-2-tetrahydrofurfuryl-5,9-dimethyl-6,7-benzomorphan diastereomers.
    Klein P; Nelson WL
    J Med Chem; 1991 Aug; 34(8):2438-44. PubMed ID: 1652019
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Identification and exploitation of the sigma-opiate pharmacophore.
    Glennon RA; Smith JD; Ismaiel AM; el-Ashmawy M; Battaglia G; Fischer JB
    J Med Chem; 1991 Mar; 34(3):1094-8. PubMed ID: 1848295
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis and evaluation of N-substituted cis-N-methyl-2-(1-pyrrolidinyl)cyclohexylamines as high affinity sigma receptor ligands. Identification of a new class of highly potent and selective sigma receptor probes.
    de Costa BR; Rice KC; Bowen WD; Thurkauf A; Rothman RB; Band L; Jacobson AE; Radesca L; Contreras PC; Gray NM
    J Med Chem; 1990 Nov; 33(11):3100-10. PubMed ID: 2172538
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Norbenzomorphan Framework as a Novel Scaffold for Generating Sigma 2 Receptor/PGRMC1 Subtype-Selective Ligands.
    Sahn JJ; Hodges TR; Chan JZ; Martin SF
    ChemMedChem; 2016 Mar; 11(6):556-61. PubMed ID: 26915462
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Novel spiropiperidines as highly potent and subtype selective sigma-receptor ligands. Part 1.
    Maier CA; Wünsch B
    J Med Chem; 2002 Jan; 45(2):438-48. PubMed ID: 11784148
    [TBL] [Abstract][Full Text] [Related]  

  • 12. CB-64D and CB-184: ligands with high sigma 2 receptor affinity and subtype selectivity.
    Bowen WD; Bertha CM; Vilner BJ; Rice KC
    Eur J Pharmacol; 1995 May; 278(3):257-60. PubMed ID: 7589164
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis, configuration, and activity of isomeric 2-phenyl-2-(N-piperidinyl)bicyclo[3.1.0]hexanes at phencyclidine and sigma binding sites.
    de Costa BR; Mattson MV; George C; Linders JT
    J Med Chem; 1992 Dec; 35(25):4704-12. PubMed ID: 1469699
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A sigma-like binding site in rat pheochromocytoma (PC12) cells: decreased affinity for (+)-benzomorphans and lower molecular weight suggest a different sigma receptor form from that of guinea pig brain.
    Hellewell SB; Bowen WD
    Brain Res; 1990 Sep; 527(2):244-53. PubMed ID: 2174717
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis and biological evaluation of conformationally restricted 2-(1-pyrrolidinyl)-N-[2-(3,4-dichlorophenyl)ethyl]-N-methylethylenediam ines as sigma receptor ligands. 1. Pyrrolidine, piperidine, homopiperidine, and tetrahydroisoquinoline classes.
    de Costa BR; Dominguez C; He XS; Williams W; Radesca L; Bowen W
    J Med Chem; 1992 Nov; 35(23):4334-43. PubMed ID: 1447735
    [TBL] [Abstract][Full Text] [Related]  

  • 16. (E)-8-benzylidene derivatives of 2-methyl-5-(3-hydroxyphenyl)morphans: highly selective ligands for the sigma 2 receptor subtype.
    Bertha CM; Vilner BJ; Mattson MV; Bowen WD; Becketts K; Xu H; Rothman RB; Flippen-Anderson JL; Rice KC
    J Med Chem; 1995 Nov; 38(24):4776-85. PubMed ID: 7490727
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis of bicyclic sigma receptor ligands with cytotoxic activity.
    Geiger C; Zelenka C; Weigl M; Fröhlich R; Wibbeling B; Lehmkuhl K; Schepmann D; Grünert R; Bednarski PJ; Wünsch B
    J Med Chem; 2007 Nov; 50(24):6144-53. PubMed ID: 17967001
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A multireceptorial binding reinvestigation on an extended class of sigma ligands: N-[omega-(indan-1-yl and tetralin-1-yl)alkyl] derivatives of 3,3-dimethylpiperidine reveal high affinities towards sigma1 and EBP sites.
    Berardi F; Ferorelli S; Colabufo NA; Leopoldo M; Perrone R; Tortorella V
    Bioorg Med Chem; 2001 May; 9(5):1325-35. PubMed ID: 11377189
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Stereoselective synthesis and receptor binding of conformationally restricted and flexible 2,4-disubstituted 1,3-dioxanes derived from benzomorphans.
    Wünsch B; Bauschke G; Diekmann H; Höfner G
    Arch Pharm (Weinheim); 1999 Dec; 332(12):413-21. PubMed ID: 10634091
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Antipodal alpha-N-(methyl through decyl)-N-normetazocines (5,9 alpha-dimethyl-2'-hydroxy-6,7-benzomorphans): in vitro and in vivo properties.
    May EL; Aceto MD; Bowman ER; Bentley C; Martin BR; Harris LS; Medzihradsky F; Mattson MV; Jacobson AE
    J Med Chem; 1994 Sep; 37(20):3408-18. PubMed ID: 7932569
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.