These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

104 related articles for article (PubMed ID: 10579836)

  • 1. Synthesis and biological evaluation of the first N-alkyl cage dimeric 4-aryl-1,4-dihydropyridines as novel nonpeptidic HIV-1 protease inhibitors.
    Hilgeroth A; Wiese M; Billich A
    J Med Chem; 1999 Nov; 42(22):4729-32. PubMed ID: 10579836
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis and biological evaluation of first N-alkyl syn dimeric 4-aryl-1,4-dihydropyridines as competitive HIV-1 protease inhibitors.
    Hilgeroth A; Billich A; Lilie H
    Eur J Med Chem; 2001 Apr; 36(4):367-74. PubMed ID: 11461762
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Structure-activity relationships of first bishydroxymethyl-substituted cage dimeric 4-aryl-1,4-dihydropyridines as HIV-1 protease inhibitors.
    Hilgeroth A; Lilie H
    Eur J Med Chem; 2003 May; 38(5):495-9. PubMed ID: 12767599
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Cage dimeric N-acyl- and N-acyloxy-4-aryl-1,4-dihydropyridines as first representatives of a novel class of HIV-1 protease inhibitors.
    Hilgeroth A; Billich A
    Arch Pharm (Weinheim); 1999 Nov; 332(11):380-4. PubMed ID: 10605378
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Dimeric 4-Aryl-1,4-dihydropyridines: development of a third class of nonpeptidic HIV-1 protease inhibitors.
    Hilgeroth A
    Mini Rev Med Chem; 2002 Jun; 2(3):235-45. PubMed ID: 12370065
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Comparison of azacyclic urea A-98881 as HIV-1 protease inhibitor with cage dimeric N-benzyl 4-(4-methoxyphenyl)-1,4-dihydropyridine as representative of a novel class of HIV-1 protease inhibitors: a molecular modeling study.
    Hilgeroth A; Fleischer R; Wiese M; Heinemann FW
    J Comput Aided Mol Des; 1999 May; 13(3):233-42. PubMed ID: 10216831
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Nonpeptidic potent HIV-1 protease inhibitors: (4-hydroxy-6-phenyl-2-oxo-2H- pyran-3-yl)thiomethanes that span P1-P2' subsites in a unique mode of active site binding.
    Prasad JV; Para KS; Tummino PJ; Ferguson D; McQuade TJ; Lunney EA; Rapundalo ST; Batley BL; Hingorani G; Domagala JM
    J Med Chem; 1995 Mar; 38(6):898-905. PubMed ID: 7699705
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A novel, picomolar inhibitor of human immunodeficiency virus type 1 protease.
    Sham HL; Zhao C; Stewart KD; Betebenner DA; Lin S; Park CH; Kong XP; Rosenbrook W; Herrin T; Madigan D; Vasavanonda S; Lyons N; Molla A; Saldivar A; Marsh KC; McDonald E; Wideburg NE; Denissen JF; Robins T; Kempf DJ; Plattner JJ; Norbeck DW
    J Med Chem; 1996 Jan; 39(2):392-7. PubMed ID: 8558507
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Cage dimeric 4-aryl-1,4-dihydropyridines as promising lead structures for the development of a novel class of HIV-1 protease inhibitors.
    Hilgeroth A; Billich A
    Arch Pharm (Weinheim); 1999 Jan; 332(1):3-5. PubMed ID: 10073137
    [No Abstract]   [Full Text] [Related]  

  • 10. Dimeric 4-aryl-1,4-dihydropyridines as novel HIV-1 protease inhibitors--affinities to intestinal P-glycoprotein.
    Hilgeroth A; Dressler C; Neuhoff S; Spahn-Langguth H; Langguth P
    Pharmazie; 2000 Oct; 55(10):784-5. PubMed ID: 11082847
    [No Abstract]   [Full Text] [Related]  

  • 11. Synthesis and evaluation of A-seco type triterpenoids for anti-HIV-1protease activity.
    Wei Y; Ma CM; Hattori M
    Eur J Med Chem; 2009 Oct; 44(10):4112-20. PubMed ID: 19493591
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Biological evaluation of bishydroxymethyl-substituted cage dimeric 1,4-dihydropyridines as a novel class of p-glycoprotein modulating agents in cancer cells.
    Richter M; Molnár J; Hilgeroth A
    J Med Chem; 2006 May; 49(9):2838-40. PubMed ID: 16640345
    [TBL] [Abstract][Full Text] [Related]  

  • 13. First bioanalytical evaluation of nonpeptidic cage dimeric HIV-1 protease inhibitor N-benzyl 4-aryl-1,4-dihydropyridine H17: biotransformation and toxicity on Hep G2 cells.
    Hilgeroth A; Langner A
    Arch Pharm (Weinheim); 2000 Jan; 333(1):32-4. PubMed ID: 10675987
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis and biological evaluation of novel amprenavir-based P1-substituted bi-aryl derivatives as ultra-potent HIV-1 protease inhibitors.
    Yan J; Huang N; Li S; Yang LM; Xing W; Zheng YT; Hu Y
    Bioorg Med Chem Lett; 2012 Mar; 22(5):1976-9. PubMed ID: 22306123
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Structure-based design of HIV protease inhibitors: 5,6-dihydro-4-hydroxy-2-pyrones as effective, nonpeptidic inhibitors.
    Thaisrivongs S; Romero DL; Tommasi RA; Janakiraman MN; Strohbach JW; Turner SR; Biles C; Morge RR; Johnson PD; Aristoff PA; Tomich PK; Lynn JC; Horng MM; Chong KT; Hinshaw RR; Howe WJ; Finzel BC; Watenpaugh KD
    J Med Chem; 1996 Nov; 39(23):4630-42. PubMed ID: 8917652
    [TBL] [Abstract][Full Text] [Related]  

  • 16. 4-hydroxy-5,6-dihydro-2H-pyran-2-ones.3. Bicyclic and hetero-aromatic ring systems as 3-position scaffolds to bind to S1' and S2' of the HIV-1 protease enzyme.
    Ellsworth EL; Domagala J; Prasad JV; Hagen S; Ferguson D; Holler T; Hupe D; Graham N; Nouhan C; Tummino PJ; Zeikus G; Lunney EA
    Bioorg Med Chem Lett; 1999 Jul; 9(14):2019-24. PubMed ID: 10450973
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Cyclic sulfamide HIV-1 protease inhibitors, with sidechains spanning from P2/P2' to P1/P1'.
    Ax A; Schaal W; Vrang L; Samuelsson B; Hallberg A; Karlén A
    Bioorg Med Chem; 2005 Feb; 13(3):755-64. PubMed ID: 15653343
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis and activity of N-benzyl pseudopeptides HIV protease inhibitors.
    Marastoni M; Bazzaro M; Bortolotti F; Tomatis R
    Bioorg Med Chem; 2003 May; 11(11):2477-83. PubMed ID: 12735995
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Enamino-oxindole HIV protease inhibitors.
    Eissenstat M; Guerassina T; Gulnik S; Afonina E; Silva AM; Ludtke D; Yokoe H; Yu B; Erickson J
    Bioorg Med Chem Lett; 2012 Aug; 22(15):5078-83. PubMed ID: 22749283
    [TBL] [Abstract][Full Text] [Related]  

  • 20. 1,2,5,6-tetra-O-benzyl-D-mannitol derivatives as novel HIV protease inhibitors.
    Bouzide A; Sauvé G; Sévigny G; Yelle J
    Bioorg Med Chem Lett; 2003 Oct; 13(20):3601-5. PubMed ID: 14505679
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.