These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

127 related articles for article (PubMed ID: 10580546)

  • 1. The neurotoxic effects of methylenedioxymethamphetamine (MDMA) and its metabolites on rat brain spheroids in culture.
    Walker TM; Davenport-Jones JE; Fox RM; Atterwill CK
    Cell Biol Toxicol; 1999 Jun; 15(3):137-42. PubMed ID: 10580546
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Metabolism is required for the expression of ecstasy-induced cardiotoxicity in vitro.
    Carvalho M; Remião F; Milhazes N; Borges F; Fernandes E; Monteiro Mdo C; Gonçalves MJ; Seabra V; Amado F; Carvalho F; Bastos ML
    Chem Res Toxicol; 2004 May; 17(5):623-32. PubMed ID: 15144219
    [TBL] [Abstract][Full Text] [Related]  

  • 3. "Ecstasy"-induced toxicity in SH-SY5Y differentiated cells: role of hyperthermia and metabolites.
    Barbosa DJ; Capela JP; Silva R; Ferreira LM; Branco PS; Fernandes E; Bastos ML; Carvalho F
    Arch Toxicol; 2014 Feb; 88(2):515-31. PubMed ID: 24177245
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Glutathione and N-acetylcysteine conjugates of alpha-methyldopamine produce serotonergic neurotoxicity: possible role in methylenedioxyamphetamine-mediated neurotoxicity.
    Bai F; Lau SS; Monks TJ
    Chem Res Toxicol; 1999 Dec; 12(12):1150-7. PubMed ID: 10604863
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Disposition of methylenedioxymethamphetamine and three metabolites in the brains of different rat strains and their possible roles in acute serotonin depletion.
    Chu T; Kumagai Y; DiStefano EW; Cho AK
    Biochem Pharmacol; 1996 Mar; 51(6):789-96. PubMed ID: 8602874
    [TBL] [Abstract][Full Text] [Related]  

  • 6. 2,5-Bis-(glutathion-S-yl)-alpha-methyldopamine, a putative metabolite of (+/-)-3,4-methylenedioxyamphetamine, decreases brain serotonin concentrations.
    Miller RT; Lau SS; Monks TJ
    Eur J Pharmacol; 1997 Apr; 323(2-3):173-80. PubMed ID: 9128836
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Serotonergic neurotoxicity of 3,4-(+/-)-methylenedioxyamphetamine and 3,4-(+/-)-methylendioxymethamphetamine (ecstasy) is potentiated by inhibition of gamma-glutamyl transpeptidase.
    Bai F; Jones DC; Lau SS; Monks TJ
    Chem Res Toxicol; 2001 Jul; 14(7):863-70. PubMed ID: 11453733
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Further studies on the role of metabolites in (+/-)-3,4-methylenedioxymethamphetamine-induced serotonergic neurotoxicity.
    Mueller M; Yuan J; Felim A; Neudörffer A; Peters FT; Maurer HH; McCann UD; Largeron M; Ricaurte GA
    Drug Metab Dispos; 2009 Oct; 37(10):2079-86. PubMed ID: 19628751
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Neurotoxicity mechanisms of thioether ecstasy metabolites.
    Capela JP; Macedo C; Branco PS; Ferreira LM; Lobo AM; Fernandes E; Remião F; Bastos ML; Dirnagl U; Meisel A; Carvalho F
    Neuroscience; 2007 Jun; 146(4):1743-57. PubMed ID: 17467183
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Liquid chromatographic-electrospray ionization mass spectrometric assay for simultaneous determination of 3,4-methylenedioxymethamphetamine and its metabolites 3,4-methylenedioxyamphetamine, 3,4-dihydroxymethamphetamine, and 4-hydroxy-3-methoxymethamphetamine in rat brain.
    Mueller M; Peters FT; Ricaurte GA; Maurer HH
    J Chromatogr B Analyt Technol Biomed Life Sci; 2008 Oct; 874(1-2):119-24. PubMed ID: 18829400
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Induction of glutathione synthesis and conjugation by 3,4-methylenedioxymethamphetamine (MDMA) and 3,4-dihydroxymethamphetamine (HHMA) in human and rat liver cells, including the protective role of some antioxidants.
    Antolino-Lobo I; Meulenbelt J; Molendijk J; Nijmeijer SM; Scherpenisse P; van den Berg M; van Duursen MB
    Toxicology; 2011 Nov; 289(2-3):175-84. PubMed ID: 21871945
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Glial cell response to 3,4-(+/-)-methylenedioxymethamphetamine and its metabolites.
    Herndon JM; Cholanians AB; Lau SS; Monks TJ
    Toxicol Sci; 2014 Mar; 138(1):130-8. PubMed ID: 24299738
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Hepatotoxicity of 3,4-methylenedioxyamphetamine and alpha-methyldopamine in isolated rat hepatocytes: formation of glutathione conjugates.
    Carvalho M; Milhazes N; Remião F; Borges F; Fernandes E; Amado F; Monks TJ; Carvalho F; Bastos ML
    Arch Toxicol; 2004 Jan; 78(1):16-24. PubMed ID: 14586543
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Serotonergic neurotoxic metabolites of ecstasy identified in rat brain.
    Jones DC; Duvauchelle C; Ikegami A; Olsen CM; Lau SS; de la Torre R; Monks TJ
    J Pharmacol Exp Ther; 2005 Apr; 313(1):422-31. PubMed ID: 15634943
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis, in vitro formation, and behavioural effects of glutathione regioisomers of alpha-methyldopamine with relevance to MDA and MDMA (ecstasy).
    Easton N; Fry J; O'Shea E; Watkins A; Kingston S; Marsden CA
    Brain Res; 2003 Oct; 987(2):144-54. PubMed ID: 14499958
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The hyperthermic and neurotoxic effects of 'Ecstasy' (MDMA) and 3,4 methylenedioxyamphetamine (MDA) in the Dark Agouti (DA) rat, a model of the CYP2D6 poor metabolizer phenotype.
    Colado MI; Williams JL; Green AR
    Br J Pharmacol; 1995 Aug; 115(7):1281-9. PubMed ID: 7582557
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Serotonergic neurotoxicity of methylenedioxyamphetamine and methylenedioxymetamphetamine.
    Monks TJ; Bai F; Miller RT; Lau SS
    Adv Exp Med Biol; 2001; 500():397-406. PubMed ID: 11764973
    [No Abstract]   [Full Text] [Related]  

  • 18. Effects of MDMA (ecstasy) and two of its metabolites on rat embryos in vitro.
    Barenys M; Flick B; Boix N; Almeida B; Joglar J; Klug S; Llobet JM
    Reprod Toxicol; 2012 Aug; 34(1):57-65. PubMed ID: 22391229
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Assessment of the role of alpha-methylepinine in the neurotoxicity of MDMA.
    Steele TD; Brewster WK; Johnson MP; Nichols DE; Yim GK
    Pharmacol Biochem Behav; 1991 Feb; 38(2):345-51. PubMed ID: 1676172
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Single oral doses of (±) 3,4-methylenedioxymethamphetamine ('Ecstasy') produce lasting serotonergic deficits in non-human primates: relationship to plasma drug and metabolite concentrations.
    Mueller M; Yuan J; McCann UD; Hatzidimitriou G; Ricaurte GA
    Int J Neuropsychopharmacol; 2013 May; 16(4):791-801. PubMed ID: 22824226
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.