BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

123 related articles for article (PubMed ID: 10585585)

  • 1. Determinants of O(6)-alkylguanine-DNA alkyltransferase activity in normal and tumour tissue from human colon and rectum.
    Povey AC; Hall CN; Cooper DP; O'Connor PJ; Margison GP
    Int J Cancer; 2000 Jan; 85(1):68-72. PubMed ID: 10585585
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Host determinants of DNA alkylation and DNA repair activity in human colorectal tissue: O(6)-methylguanine levels are associated with GSTT1 genotype and O(6)-alkylguanine-DNA alkyltransferase activity with CYP2D6 genotype.
    Povey AC; Hall CN; Badawi AF; Cooper DP; Guppy MJ; Jackson PE; O'Connor PJ; Margison GP
    Mutat Res; 2001 Aug; 495(1-2):103-15. PubMed ID: 11448648
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Longitudinal variation in O(6)-alkylguanine DNA-alkyltransferase activity in the human colon and rectum.
    Lees NP; Harrison KL; Hill E; Hall CN; Margison GP; Povey AC
    Br J Cancer; 2002 Jul; 87(2):168-70. PubMed ID: 12107837
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Low O6-alkylguanine DNA-alkyltransferase activity in normal colorectal tissue is associated with colorectal tumours containing a GC-->AT transition in the K-ras oncogene.
    Jackson PE; Hall CN; O'Connor PJ; Cooper DP; Margison GP; Povey AC
    Carcinogenesis; 1997 Jul; 18(7):1299-302. PubMed ID: 9230271
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Determinants of O6-alkylguanine-DNA alkyltransferase activity in human colon cancer.
    Gerson SL; Allay E; Vitantonio K; Dumenco LL
    Clin Cancer Res; 1995 May; 1(5):519-25. PubMed ID: 9816011
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Formation and persistence of O(6)-methylguanine in the mouse colon following treatment with 1,2-dimethylhydrazine as measured by an O(6)-alkylguanine-DNA alkyltransferase inactivation assay.
    Jackson PE; Cooper DP; Meyer TA; Wood M; Povey AC; Margison GP
    Toxicol Lett; 2000 Jun; 115(3):205-12. PubMed ID: 10814890
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Tissue-specific expression and induction of human O6-alkylguanine-DNA alkyltransferase in transgenic mice.
    Rafferty JA; Fan CY; Potter PM; Watson AJ; Cawkwell L; O'Connor PJ; Margison GP
    Mol Carcinog; 1992; 6(1):26-31. PubMed ID: 1503642
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Quantitative immunohistochemical estimates of O6-alkylguanine-DNA alkyltransferase expression in normal and malignant human colon.
    Zaidi NH; Liu L; Gerson SL
    Clin Cancer Res; 1996 Mar; 2(3):577-84. PubMed ID: 9816206
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Differential expression of the O6-alkylguanine-DNA alkyltransferase gene in normal human breast and skin tissue: in situ mapping of cell type-specific expression.
    Wani G; D'Ambrosio SM
    Mol Carcinog; 1995 Mar; 12(3):177-84. PubMed ID: 7893370
    [TBL] [Abstract][Full Text] [Related]  

  • 10. In vivo depletion of O6-alkylguanine-DNA-alkyltransferase in lymphocytes and melanoma of patients treated with CB 10-277, a new DTIC analogue.
    Lee SM; Thatcher N; Crowther D; Margison GP
    Cancer Chemother Pharmacol; 1992; 31(3):240-6. PubMed ID: 1464162
    [TBL] [Abstract][Full Text] [Related]  

  • 11. O6-alkylguanine-DNA alkyltransferase activity in schistosomiasis-associated human bladder cancer.
    Badawi AF; Cooper DP; Mostafa MH; Aboul-Azm T; Barnard R; Margison GP; O'Connor PJ
    Eur J Cancer; 1994; 30A(9):1314-9. PubMed ID: 7999420
    [TBL] [Abstract][Full Text] [Related]  

  • 12. O6-alkylguanine-DNA-alkyltransferase activity and nitrosourea sensitivity in human cancer cell lines.
    Walker MC; Masters JR; Margison GP
    Br J Cancer; 1992 Nov; 66(5):840-3. PubMed ID: 1419626
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Expression of O6-alkylguanine-DNA-alkyltransferase in situ in ovarian and Hodgkin's tumours.
    Lee SM; Harris M; Rennison J; McGown A; Bromley M; Elder RH; Rafferty JA; Crowther D; Margison GP
    Eur J Cancer; 1993; 29A(9):1306-12. PubMed ID: 8343274
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Inactivation of O6-alkylguanine-DNA alkyltransferase in human peripheral blood mononuclear cells by temozolomide.
    Lee SM; Thatcher N; Crowther D; Margison GP
    Br J Cancer; 1994 Mar; 69(3):452-6. PubMed ID: 8123472
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Activity of fotemustine in medulloblastoma and malignant glioma xenografts in relation to O6-alkylguanine-DNA alkyltransferase and alkylpurine-DNA N-glycosylase activity.
    Vassal G; Boland I; Terrier-Lacombe MJ; Watson AJ; Margison GP; Vénuat AM; Morizet J; Parker F; Lacroix C; Lellouch-Tubiana A; Pierre-Kahn A; Poullain MG; Gouyette A
    Clin Cancer Res; 1998 Feb; 4(2):463-8. PubMed ID: 9516937
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Cell type-specific expression of the O6-alkylguanine-DNA alkyltransferase gene in normal human liver tissues as revealed by in situ hybridization.
    Wani G; Wani AA; D'Ambrosio SM
    Carcinogenesis; 1993 Apr; 14(4):737-41. PubMed ID: 8472340
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Upregulation of O6-alkylguanine-DNA-alkyltransferase expression and the presence of double minute chromosomes in alkylating agent selected Chinese hamster cells.
    Morten JE; Bayley L; Watson AJ; Ward TH; Potter PM; Rafferty JA; Margison GP
    Carcinogenesis; 1992 Mar; 13(3):483-7. PubMed ID: 1312399
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Mammalian cells expressing Escherichia coli O6-alkylguanine-DNA alkyltransferases are hypersensitive to dibromoalkanes.
    Abril N; Margison GP
    Chem Res Toxicol; 1999 Jun; 12(6):544-51. PubMed ID: 10368318
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Variability and regulation of O6-alkylguanine-DNA alkyltransferase.
    Margison GP; Povey AC; Kaina B; Santibáñez Koref MF
    Carcinogenesis; 2003 Apr; 24(4):625-35. PubMed ID: 12727789
    [TBL] [Abstract][Full Text] [Related]  

  • 20. O6-Alkylguanine-DNA alkyltransferase in normal colon tissue and colon cancer.
    White A; Kibitel J; Garcia Y; Belanich M; Yarosh D; Wideroff J; Levin L; Held D; Fuchs A; Citron M
    Oncol Res; 1997; 9(3):149-53. PubMed ID: 9220500
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.