BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

251 related articles for article (PubMed ID: 10587526)

  • 1. Overexpression of monocarboxylate transporter and lactate dehydrogenase alters insulin secretory responses to pyruvate and lactate in beta cells.
    Ishihara H; Wang H; Drewes LR; Wollheim CB
    J Clin Invest; 1999 Dec; 104(11):1621-9. PubMed ID: 10587526
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Importance of lactate dehydrogenase for the regulation of glycolytic flux and insulin secretion in insulin-producing cells.
    Alcazar O; Tiedge M; Lenzen S
    Biochem J; 2000 Dec; 352 Pt 2(Pt 2):373-80. PubMed ID: 11085930
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Overexpression of lactate dehydrogenase A attenuates glucose-induced insulin secretion in stable MIN-6 beta-cell lines.
    Zhao C; Rutter GA
    FEBS Lett; 1998 Jul; 430(3):213-6. PubMed ID: 9688541
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Low lactate dehydrogenase and high mitochondrial glycerol phosphate dehydrogenase in pancreatic beta-cells. Potential role in nutrient sensing.
    Sekine N; Cirulli V; Regazzi R; Brown LJ; Gine E; Tamarit-Rodriguez J; Girotti M; Marie S; MacDonald MJ; Wollheim CB
    J Biol Chem; 1994 Feb; 269(7):4895-902. PubMed ID: 8106462
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Acute overexpression of lactate dehydrogenase-A perturbs beta-cell mitochondrial metabolism and insulin secretion.
    Ainscow EK; Zhao C; Rutter GA
    Diabetes; 2000 Jul; 49(7):1149-55. PubMed ID: 10909972
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Glucose-stimulated insulin secretion does not require activation of pyruvate dehydrogenase: impact of adenovirus-mediated overexpression of PDH kinase and PDH phosphate phosphatase in pancreatic islets.
    Nicholls LI; Ainscow EK; Rutter GA
    Biochem Biophys Res Commun; 2002 Mar; 291(4):1081-8. PubMed ID: 11866475
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Insulin secretion profiles are modified by overexpression of glutamate dehydrogenase in pancreatic islets.
    Carobbio S; Ishihara H; Fernandez-Pascual S; Bartley C; Martin-Del-Rio R; Maechler P
    Diabetologia; 2004 Feb; 47(2):266-76. PubMed ID: 14689183
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Lactate transport in insulin-secreting beta-cells: contrast between rat islets and HIT-T15 insulinoma cells.
    Best L; Trebilcock R; Tomlinson S
    Mol Cell Endocrinol; 1992 Jul; 86(1-2):49-56. PubMed ID: 1324857
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Fundamental metabolic differences between hepatocytes and islet beta-cells revealed by glucokinase overexpression.
    Berman HK; Newgard CB
    Biochemistry; 1998 Mar; 37(13):4543-52. PubMed ID: 9521775
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Overexpression of mitochondrial FAD-linked glycerol-3-phosphate dehydrogenase does not correct glucose-stimulated insulin secretion from diabetic GK rat pancreatic islets.
    Ueda K; Tanizawa Y; Ishihara H; Kizuki N; Ohta Y; Matsutani A; Oka Y
    Diabetologia; 1998 Jun; 41(6):649-53. PubMed ID: 9662045
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Overexpression of G11alpha and isoforms of phospholipase C in islet beta-cells reveals a lack of correlation between inositol phosphate accumulation and insulin secretion.
    Gasa R; Trinh KY; Yu K; Wilkie TM; Newgard CB
    Diabetes; 1999 May; 48(5):1035-44. PubMed ID: 10331408
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Expression and distribution of lactate/monocarboxylate transporter isoforms in pancreatic islets and the exocrine pancreas.
    Zhao C; Wilson MC; Schuit F; Halestrap AP; Rutter GA
    Diabetes; 2001 Feb; 50(2):361-6. PubMed ID: 11272148
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Silencing of the mitochondrial NADH shuttle component aspartate-glutamate carrier AGC1/Aralar1 in INS-1E cells and rat islets.
    Casimir M; Rubi B; Frigerio F; Chaffard G; Maechler P
    Biochem J; 2009 Dec; 424(3):459-66. PubMed ID: 19764902
    [TBL] [Abstract][Full Text] [Related]  

  • 14. What couples glycolysis to mitochondrial signal generation in glucose-stimulated insulin secretion?
    Ishihara H; Wollheim CB
    IUBMB Life; 2000 May; 49(5):391-5. PubMed ID: 10902570
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Blood flow in endogenous and transplanted pancreatic islets in anesthetized rats: effects of lactate and pyruvate.
    Barbu A; Johansson Å; Bodin B; Källskog Ö; Carlsson PO; Sandberg M; Börjesson JL; Jansson L
    Pancreas; 2012 Nov; 41(8):1263-71. PubMed ID: 22617710
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The malate-aspartate NADH shuttle member Aralar1 determines glucose metabolic fate, mitochondrial activity, and insulin secretion in beta cells.
    Rubi B; del Arco A; Bartley C; Satrustegui J; Maechler P
    J Biol Chem; 2004 Dec; 279(53):55659-66. PubMed ID: 15494407
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The anti-tumour agent lonidamine is a potent inhibitor of the mitochondrial pyruvate carrier and plasma membrane monocarboxylate transporters.
    Nancolas B; Guo L; Zhou R; Nath K; Nelson DS; Leeper DB; Blair IA; Glickson JD; Halestrap AP
    Biochem J; 2016 Apr; 473(7):929-36. PubMed ID: 26831515
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Engineering of glycerol-stimulated insulin secretion in islet beta cells. Differential metabolic fates of glucose and glycerol provide insight into mechanisms of stimulus-secretion coupling.
    Noel RJ; Antinozzi PA; McGarry JD; Newgard CB
    J Biol Chem; 1997 Jul; 272(30):18621-7. PubMed ID: 9228030
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Glucose sensitivity and metabolism-secretion coupling studied during two-year continuous culture in INS-1E insulinoma cells.
    Merglen A; Theander S; Rubi B; Chaffard G; Wollheim CB; Maechler P
    Endocrinology; 2004 Feb; 145(2):667-78. PubMed ID: 14592952
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Increasing triglyceride synthesis inhibits glucose-induced insulin secretion in isolated rat islets of langerhans: a study using adenoviral expression of diacylglycerol acyltransferase.
    Kelpe CL; Johnson LM; Poitout V
    Endocrinology; 2002 Sep; 143(9):3326-32. PubMed ID: 12193544
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.