212 related articles for article (PubMed ID: 10588655)
1. Roles for basal and stimulated p21(Cip-1/WAF1/MDA6) expression and mitogen-activated protein kinase signaling in radiation-induced cell cycle checkpoint control in carcinoma cells.
Park JS; Carter S; Reardon DB; Schmidt-Ullrich R; Dent P; Fisher PB
Mol Biol Cell; 1999 Dec; 10(12):4231-46. PubMed ID: 10588655
[TBL] [Abstract][Full Text] [Related]
2. Pharmocologic inhibitors of the mitogen activated protein kinase cascade have the potential to interact with ionizing radiation exposure to induce cell death in carcinoma cells by multiple mechanisms.
Qiao L; Yacoub A; McKinstry R; Park JS; Caron R; Fisher PB; Hagan MP; Grant S; Dent P
Cancer Biol Ther; 2002; 1(2):168-76. PubMed ID: 12170777
[TBL] [Abstract][Full Text] [Related]
3. Radiation-induced release of transforming growth factor alpha activates the epidermal growth factor receptor and mitogen-activated protein kinase pathway in carcinoma cells, leading to increased proliferation and protection from radiation-induced cell death.
Dent P; Reardon DB; Park JS; Bowers G; Logsdon C; Valerie K; Schmidt-Ullrich R
Mol Biol Cell; 1999 Aug; 10(8):2493-506. PubMed ID: 10436007
[TBL] [Abstract][Full Text] [Related]
4. Inhibitors of MEK1/2 interact with UCN-01 to induce apoptosis and reduce colony formation in mammary and prostate carcinoma cells.
McKinstry R; Qiao L; Yacoub A; Dai Y; Decker R; Holt S; Hagan MP; Grant S; Dent P
Cancer Biol Ther; 2002; 1(3):243-53. PubMed ID: 12432271
[TBL] [Abstract][Full Text] [Related]
5. Inhibition of the mitogen activated protein (MAP) kinase cascade potentiates cell killing by low dose ionizing radiation in A431 human squamous carcinoma cells.
Carter S; Auer KL; Reardon DB; Birrer M; Fisher PB; Valerie K; Schmidt-Ullrich R; Mikkelsen R; Dent P
Oncogene; 1998 May; 16(21):2787-96. PubMed ID: 9652746
[TBL] [Abstract][Full Text] [Related]
6. Expression of human papilloma virus E7 protein causes apoptosis and inhibits DNA synthesis in primary hepatocytes via increased expression of p21(Cip-1/WAF1/MDA6).
Park JS; Boyer S; Mitchell K; Gilfor D; Birrer M; Darlington G; El Deiry W; Firestone GL; Munger K; Band V; Fisher PB; Dent P
J Biol Chem; 2000 Jan; 275(1):18-28. PubMed ID: 10617580
[TBL] [Abstract][Full Text] [Related]
7. Inhibition of the mitogen activated protein kinase pathway potentiates radiation-induced cell killing via cell cycle arrest at the G2/M transition and independently of increased signaling by the JNK/c-Jun pathway.
Cartee L; Vrana JA; Wang Z; Park JS; Birrer M; Fisher PB; Grant S; Dent P
Int J Oncol; 2000 Feb; 16(2):413-22. PubMed ID: 10639586
[TBL] [Abstract][Full Text] [Related]
8. Hepatitis B virus X protein increases expression of p21(Cip-1/WAF1/MDA6) and p27(Kip-1) in primary mouse hepatocytes, leading to reduced cell cycle progression.
Qiao L; Leach K; McKinstry R; Gilfor D; Yacoub A; Park JS; Grant S; Hylemon PB; Fisher PB; Dent P
Hepatology; 2001 Nov; 34(5):906-17. PubMed ID: 11679961
[TBL] [Abstract][Full Text] [Related]
9. Importance of MEK-1/-2 signaling in monocytic and granulocytic differentiation of myeloid cell lines.
Miranda MB; McGuire TF; Johnson DE
Leukemia; 2002 Apr; 16(4):683-92. PubMed ID: 11960350
[TBL] [Abstract][Full Text] [Related]
10. A role for both Ets and C/EBP transcription factors and mRNA stabilization in the MAPK-dependent increase in p21 (Cip-1/WAF1/mda6) protein levels in primary hepatocytes.
Park JS; Qiao L; Gilfor D; Yang MY; Hylemon PB; Benz C; Darlington G; Firestone G; Fisher PB; Dent P
Mol Biol Cell; 2000 Sep; 11(9):2915-32. PubMed ID: 10982390
[TBL] [Abstract][Full Text] [Related]
11. Pharmacologic mitogen-activated protein/extracellular signal-regulated kinase kinase/mitogen-activated protein kinase inhibitors interact synergistically with STI571 to induce apoptosis in Bcr/Abl-expressing human leukemia cells.
Yu C; Krystal G; Varticovksi L; McKinstry R; Rahmani M; Dent P; Grant S
Cancer Res; 2002 Jan; 62(1):188-99. PubMed ID: 11782377
[TBL] [Abstract][Full Text] [Related]
12. The mitogen-activated protein (MAP) kinase cascade can either stimulate or inhibit DNA synthesis in primary cultures of rat hepatocytes depending upon whether its activation is acute/phasic or chronic.
Tombes RM; Auer KL; Mikkelsen R; Valerie K; Wymann MP; Marshall CJ; McMahon M; Dent P
Biochem J; 1998 Mar; 330 ( Pt 3)(Pt 3):1451-60. PubMed ID: 9494119
[TBL] [Abstract][Full Text] [Related]
13. Cell cycle arrest mediated by the MEK/mitogen-activated protein kinase pathway.
Pumiglia KM; Decker SJ
Proc Natl Acad Sci U S A; 1997 Jan; 94(2):448-52. PubMed ID: 9012803
[TBL] [Abstract][Full Text] [Related]
14. Ionizing radiation-induced mitogen-activated protein (MAP) kinase activation in DU145 prostate carcinoma cells: MAP kinase inhibition enhances radiation-induced cell killing and G2/M-phase arrest.
Hagan M; Wang L; Hanley JR; Park JS; Dent P
Radiat Res; 2000 Apr; 153(4):371-83. PubMed ID: 10760996
[TBL] [Abstract][Full Text] [Related]
15. Prolonged induction of p21Cip1/WAF1/CDK2/PCNA complex by epidermal growth factor receptor activation mediates ligand-induced A431 cell growth inhibition.
Fan Z; Lu Y; Wu X; DeBlasio A; Koff A; Mendelsohn J
J Cell Biol; 1995 Oct; 131(1):235-42. PubMed ID: 7559780
[TBL] [Abstract][Full Text] [Related]
16. A p21(waf1)-independent pathway for inhibitory phosphorylation of cyclin-dependent kinase p34(cdc2) and concomitant G(2)/M arrest by the chemopreventive flavonoid apigenin.
McVean M; Weinberg WC; Pelling JC
Mol Carcinog; 2002 Jan; 33(1):36-43. PubMed ID: 11807956
[TBL] [Abstract][Full Text] [Related]
17. Mutated p21(WAF1/CIP1/SDI1) lacking CDK-inhibitory activity fails to prevent apoptosis in human colorectal carcinoma cells.
Lu Y; Yamagishi N; Yagi T; Takebe H
Oncogene; 1998 Feb; 16(6):705-12. PubMed ID: 9488034
[TBL] [Abstract][Full Text] [Related]
18. G1 phase accumulation induced by UCN-01 is associated with dephosphorylation of Rb and CDK2 proteins as well as induction of CDK inhibitor p21/Cip1/WAF1/Sdi1 in p53-mutated human epidermoid carcinoma A431 cells.
Akiyama T; Yoshida T; Tsujita T; Shimizu M; Mizukami T; Okabe M; Akinaga S
Cancer Res; 1997 Apr; 57(8):1495-501. PubMed ID: 9108451
[TBL] [Abstract][Full Text] [Related]
19. Pharmacological inhibitors of the mitogen-activated protein kinase (MAPK) kinase/MAPK cascade interact synergistically with UCN-01 to induce mitochondrial dysfunction and apoptosis in human leukemia cells.
Dai Y; Yu C; Singh V; Tang L; Wang Z; McInistry R; Dent P; Grant S
Cancer Res; 2001 Jul; 61(13):5106-15. PubMed ID: 11431348
[TBL] [Abstract][Full Text] [Related]
20. Transient suppression of nuclear Cdc2 activity in response to ionizing radiation.
Kim MJ; Lee JY; Lee SJ
Oncol Rep; 2008 May; 19(5):1323-9. PubMed ID: 18425394
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
