BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

221 related articles for article (PubMed ID: 10594034)

  • 1. Biological characteristics of the leukemia-associated transcriptional factor AML1 disclosed by hematopoietic rescue of AML1-deficient embryonic stem cells by using a knock-in strategy.
    Okuda T; Takeda K; Fujita Y; Nishimura M; Yagyu S; Yoshida M; Akira S; Downing JR; Abe T
    Mol Cell Biol; 2000 Jan; 20(1):319-28. PubMed ID: 10594034
    [TBL] [Abstract][Full Text] [Related]  

  • 2. VWRPY motif-dependent and -independent roles of AML1/Runx1 transcription factor in murine hematopoietic development.
    Nishimura M; Fukushima-Nakase Y; Fujita Y; Nakao M; Toda S; Kitamura N; Abe T; Okuda T
    Blood; 2004 Jan; 103(2):562-70. PubMed ID: 14504086
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The transcriptionally active form of AML1 is required for hematopoietic rescue of the AML1-deficient embryonic para-aortic splanchnopleural (P-Sp) region.
    Goyama S; Yamaguchi Y; Imai Y; Kawazu M; Nakagawa M; Asai T; Kumano K; Mitani K; Ogawa S; Chiba S; Kurokawa M; Hirai H
    Blood; 2004 Dec; 104(12):3558-64. PubMed ID: 15271791
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Identification of an alternatively spliced form of the mouse AML1/RUNX1 gene transcript AML1c and its expression in early hematopoietic development.
    Fujita Y; Nishimura M; Taniwaki M; Abe T; Okuda T
    Biochem Biophys Res Commun; 2001 Mar; 281(5):1248-55. PubMed ID: 11243869
    [TBL] [Abstract][Full Text] [Related]  

  • 5. AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis.
    Okuda T; van Deursen J; Hiebert SW; Grosveld G; Downing JR
    Cell; 1996 Jan; 84(2):321-30. PubMed ID: 8565077
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Core-binding factor beta (CBFbeta), but not CBFbeta-smooth muscle myosin heavy chain, rescues definitive hematopoiesis in CBFbeta-deficient embryonic stem cells.
    Miller JD; Stacy T; Liu PP; Speck NA
    Blood; 2001 Apr; 97(8):2248-56. PubMed ID: 11290585
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Expression of a knocked-in AML1-ETO leukemia gene inhibits the establishment of normal definitive hematopoiesis and directly generates dysplastic hematopoietic progenitors.
    Okuda T; Cai Z; Yang S; Lenny N; Lyu CJ; van Deursen JM; Harada H; Downing JR
    Blood; 1998 May; 91(9):3134-43. PubMed ID: 9558367
    [TBL] [Abstract][Full Text] [Related]  

  • 8. An acute myeloid leukemia gene, AML1, regulates transcriptional activation and hemopoietic myeloid cell differentiation antagonistically by two alternative spliced forms.
    Tanaka T; Tanaka K; Ogawa S; Kurokawa M; Mitani K; Yazaki Y; Shibata Y; Hirai H
    Leukemia; 1997 Apr; 11 Suppl 3():299-302. PubMed ID: 9209372
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Exogenous cdk4 overcomes reduced cdk4 RNA and inhibition of G1 progression in hematopoietic cells expressing a dominant-negative CBF - a model for overcoming inhibition of proliferation by CBF oncoproteins.
    Lou J; Cao W; Bernardin F; Ayyanathan K; RauscherIII FJ; Friedman AD
    Oncogene; 2000 May; 19(22):2695-703. PubMed ID: 10851069
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Hematopoiesis in the fetal liver is impaired by targeted mutagenesis of a gene encoding a non-DNA binding subunit of the transcription factor, polyomavirus enhancer binding protein 2/core binding factor.
    Niki M; Okada H; Takano H; Kuno J; Tani K; Hibino H; Asano S; Ito Y; Satake M; Noda T
    Proc Natl Acad Sci U S A; 1997 May; 94(11):5697-702. PubMed ID: 9159135
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A novel transcript encoding an N-terminally truncated AML1/PEBP2 alphaB protein interferes with transactivation and blocks granulocytic differentiation of 32Dcl3 myeloid cells.
    Zhang YW; Bae SC; Huang G; Fu YX; Lu J; Ahn MY; Kanno Y; Kanno T; Ito Y
    Mol Cell Biol; 1997 Jul; 17(7):4133-45. PubMed ID: 9199349
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Inability of RUNX1/AML1 to breach AML1-ETO block of embryonic stem cell definitive hematopoiesis.
    Peterson LF; Lo MC; Okumura AJ; Zhang DE
    Blood Cells Mol Dis; 2007; 39(3):321-8. PubMed ID: 17692541
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The AML1 gene: a transcription factor involved in the pathogenesis of myeloid and lymphoid leukemias.
    Lo Coco F; Pisegna S; Diverio D
    Haematologica; 1997; 82(3):364-70. PubMed ID: 9234595
    [TBL] [Abstract][Full Text] [Related]  

  • 14. TLE, the human homolog of groucho, interacts with AML1 and acts as a repressor of AML1-induced transactivation.
    Imai Y; Kurokawa M; Tanaka K; Friedman AD; Ogawa S; Mitani K; Yazaki Y; Hirai H
    Biochem Biophys Res Commun; 1998 Nov; 252(3):582-9. PubMed ID: 9837750
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Expression of a conditional AML1-ETO oncogene bypasses embryonic lethality and establishes a murine model of human t(8;21) acute myeloid leukemia.
    Higuchi M; O'Brien D; Kumaravelu P; Lenny N; Yeoh EJ; Downing JR
    Cancer Cell; 2002 Feb; 1(1):63-74. PubMed ID: 12086889
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Haploinsufficiency of AML1 affects the temporal and spatial generation of hematopoietic stem cells in the mouse embryo.
    Cai Z; de Bruijn M; Ma X; Dortland B; Luteijn T; Downing RJ; Dzierzak E
    Immunity; 2000 Oct; 13(4):423-31. PubMed ID: 11070161
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Rearrangement of the AML1/CBFA2 gene in myeloid leukemia with the 3;21 translocation: expression of co-existing multiple chimeric genes with similar functions as transcriptional repressors, but with opposite tumorigenic properties.
    Zent C; Kim N; Hiebert S; Zhang DE; Tenen DG; Rowley JD; Nucifora G
    Curr Top Microbiol Immunol; 1996; 211():243-52. PubMed ID: 8585955
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The role of the AML1 transcription factor in leukemogenesis.
    Lorsbach RB; Downing JR
    Int J Hematol; 2001 Oct; 74(3):258-65. PubMed ID: 11721960
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The AML1 transcription factor functions to develop and maintain hematogenic precursor cells in the embryonic aorta-gonad-mesonephros region.
    Mukouyama Y; Chiba N; Hara T; Okada H; Ito Y; Kanamaru R; Miyajima A; Satake M; Watanabe T
    Dev Biol; 2000 Apr; 220(1):27-36. PubMed ID: 10720428
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Dysplastic definitive hematopoiesis in AML1/EVI1 knock-in embryos.
    Maki K; Yamagata T; Asai T; Yamazaki I; Oda H; Hirai H; Mitani K
    Blood; 2005 Sep; 106(6):2147-55. PubMed ID: 15914564
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.