155 related articles for article (PubMed ID: 10596756)
1. Transgenic pigs as bioreactors: a comparison of gamma-carboxylation of glutamic acid in recombinant human protein C and factor IX by the mammary gland.
Van Cott KE; Butler SP; Russell CG; Subramanian A; Lubon H; Gwazdauskas FC; Knight J; Drohan WN; Velander WH
Genet Anal; 1999 Nov; 15(3-5):155-60. PubMed ID: 10596756
[TBL] [Abstract][Full Text] [Related]
2. Rate limitations in posttranslational processing by the mammary gland of transgenic animals.
Subramanian A; Paleyanda RK; Lubon H; Williams BL; Gwazdauskas FC; Knight JW; Drohan WN; Velander WH
Ann N Y Acad Sci; 1996 May; 782():87-96. PubMed ID: 8659928
[TBL] [Abstract][Full Text] [Related]
3. Inefficient processing of human protein C in the mouse mammary gland.
Drohan WN; Zhang DW; Paleyanda RK; Chang R; Wroble M; Velander W; Lubon H
Transgenic Res; 1994 Nov; 3(6):355-64. PubMed ID: 8000432
[TBL] [Abstract][Full Text] [Related]
4. Role of the propeptide and gamma-glutamic acid domain of factor IX for in vitro carboxylation by the vitamin K-dependent carboxylase.
Stanley TB; Wu SM; Houben RJ; Mutucumarana VP; Stafford DW
Biochemistry; 1998 Sep; 37(38):13262-8. PubMed ID: 9748333
[TBL] [Abstract][Full Text] [Related]
5. The porcine mammary gland as a bioreactor for complex proteins.
Morcöl T; Akers RM; Johnson JL; Williams BL; Gwazdauskas FC; Knight JW; Lubon H; Paleyanda RK; Drohan WN; Velander WH
Ann N Y Acad Sci; 1994 May; 721():218-33. PubMed ID: 8010672
[TBL] [Abstract][Full Text] [Related]
6. Isolation of the human gamma-carboxylase and a gamma-carboxylase-associated protein from factor IX-expressing mammalian cells.
Lingenfelter SE; Berkner KL
Biochemistry; 1996 Jun; 35(25):8234-43. PubMed ID: 8679578
[TBL] [Abstract][Full Text] [Related]
7. Tethered processivity of the vitamin K-dependent carboxylase: factor IX is efficiently modified in a mechanism which distinguishes Gla's from Glu's and which accounts for comprehensive carboxylation in vivo.
Stenina O; Pudota BN; McNally BA; Hommema EL; Berkner KL
Biochemistry; 2001 Aug; 40(34):10301-9. PubMed ID: 11513608
[TBL] [Abstract][Full Text] [Related]
8. In vitro and in vivo functional characterization of bovine vitamin K-dependent gamma-carboxylase expressed in Chinese hamster ovary cells.
Rehemtulla A; Roth DA; Wasley LC; Kuliopulos A; Walsh CT; Furie B; Furie BC; Kaufman RJ
Proc Natl Acad Sci U S A; 1993 May; 90(10):4611-5. PubMed ID: 8506307
[TBL] [Abstract][Full Text] [Related]
9. Engineering protein processing of the mammary gland to produce abundant hemophilia B therapy in milk.
Zhao J; Xu W; Ross JW; Walters EM; Butler SP; Whyte JJ; Kelso L; Fatemi M; Vanderslice NC; Giroux K; Spate LD; Samuel MS; Murphy CN; Wells KD; Masiello NC; Prather RS; Velander WH
Sci Rep; 2015 Sep; 5():14176. PubMed ID: 26387706
[TBL] [Abstract][Full Text] [Related]
10. The propeptides of the vitamin K-dependent proteins possess different affinities for the vitamin K-dependent carboxylase.
Stanley TB; Jin DY; Lin PJ; Stafford DW
J Biol Chem; 1999 Jun; 274(24):16940-4. PubMed ID: 10358041
[TBL] [Abstract][Full Text] [Related]
11. Zn(2+)-selective purification of recombinant proteins from the milk of transgenic animals.
Degener A; Belew M; Velander WH
J Chromatogr A; 1998 Mar; 799(1-2):125-37. PubMed ID: 9550105
[TBL] [Abstract][Full Text] [Related]
12. The propeptides of human protein C, factor VII, and factor IX are exchangeable with regard to directing gamma-carboxylation of these proteins.
Geng JP; Castellino FJ
Thromb Haemost; 1996 Aug; 76(2):205-7. PubMed ID: 8865532
[TBL] [Abstract][Full Text] [Related]
13. Affinity purification of biologically active and inactive forms of recombinant human protein C produced in porcine mammary gland.
Van Cott KE; Williams B; Velander WH; Gwazdauskas F; Lee T; Lubon H; Drohan WN
J Mol Recognit; 1996; 9(5-6):407-14. PubMed ID: 9174918
[TBL] [Abstract][Full Text] [Related]
14. Binding of the factor IX gamma-carboxyglutamic acid domain to the vitamin K-dependent gamma-glutamyl carboxylase active site induces an allosteric effect that may ensure processive carboxylation and regulate the release of carboxylated product.
Lin PJ; Straight DL; Stafford DW
J Biol Chem; 2004 Feb; 279(8):6560-6. PubMed ID: 14660587
[TBL] [Abstract][Full Text] [Related]
15. Expression of biologically active human clotting factor IX in Drosophila S2 cells: γ-carboxylation of a human vitamin K-dependent protein by the insect enzyme.
Vatandoost J; Zomorodipour A; Sadeghizadeh M; Aliyari R; Bos MH; Ataei F
Biotechnol Prog; 2012; 28(1):45-51. PubMed ID: 22012919
[TBL] [Abstract][Full Text] [Related]
16. Recognition site directing vitamin K-dependent gamma-carboxylation resides on the propeptide of factor IX.
Jorgensen MJ; Cantor AB; Furie BC; Brown CL; Shoemaker CB; Furie B
Cell; 1987 Jan; 48(2):185-91. PubMed ID: 3802193
[TBL] [Abstract][Full Text] [Related]
17. The gamma-carboxylation recognition site is sufficient to direct vitamin K-dependent carboxylation on an adjacent glutamate-rich region of thrombin in a propeptide-thrombin chimera.
Furie BC; Ratcliffe JV; Tward J; Jorgensen MJ; Blaszkowsky LS; DiMichele D; Furie B
J Biol Chem; 1997 Nov; 272(45):28258-62. PubMed ID: 9353278
[TBL] [Abstract][Full Text] [Related]
18. Carboxylase overexpression effects full carboxylation but poor release and secretion of factor IX: implications for the release of vitamin K-dependent proteins.
Hallgren KW; Hommema EL; McNally BA; Berkner KL
Biochemistry; 2002 Dec; 41(50):15045-55. PubMed ID: 12475254
[TBL] [Abstract][Full Text] [Related]
19. A mutation in the propeptide of Factor IX leads to warfarin sensitivity by a novel mechanism.
Chu K; Wu SM; Stanley T; Stafford DW; High KA
J Clin Invest; 1996 Oct; 98(7):1619-25. PubMed ID: 8833911
[TBL] [Abstract][Full Text] [Related]
20. Glutamyl substrate-induced exposure of a free cysteine residue in the vitamin K-dependent gamma-glutamyl carboxylase is critical for vitamin K epoxidation.
Bouchard BA; Furie B; Furie BC
Biochemistry; 1999 Jul; 38(29):9517-23. PubMed ID: 10413529
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
