BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

198 related articles for article (PubMed ID: 10602497)

  • 1. Persistence of p53 mutations and resistance of keratinocytes to apoptosis are associated with the increased susceptibility of mice lacking the XPC gene to UV carcinogenesis.
    Ananthaswamy HN; Ouhtit A; Evans RL; Gorny A; Khaskina P; Sands AT; Conti CJ
    Oncogene; 1999 Dec; 18(51):7395-8. PubMed ID: 10602497
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Relationship between UV-induced mutant p53 patches and skin tumours, analysed by mutation spectra and by induction kinetics in various DNA-repair-deficient mice.
    Rebel H; Kram N; Westerman A; Banus S; van Kranen HJ; de Gruijl FR
    Carcinogenesis; 2005 Dec; 26(12):2123-30. PubMed ID: 16051635
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Ultraviolet B radiation-induced skin cancer in mice defective in the Xpc, Trp53, and Apex (HAP1) genes: genotype-specific effects on cancer predisposition and pathology of tumors.
    Cheo DL; Meira LB; Burns DK; Reis AM; Issac T; Friedberg EC
    Cancer Res; 2000 Mar; 60(6):1580-4. PubMed ID: 10749126
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Mutations in the Trp53 gene of UV-irradiated Xpc mutant mice suggest a novel Xpc-dependent DNA repair process.
    Nahari D; McDaniel LD; Task LB; Daniel RL; Velasco-Miguel S; Friedberg EC
    DNA Repair (Amst); 2004 Apr; 3(4):379-86. PubMed ID: 15010313
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Frequent recovery of triplet mutations in UVB-exposed skin epidermis of Xpc-knockout mice.
    Ikehata H; Saito Y; Yanase F; Mori T; Nikaido O; Ono T
    DNA Repair (Amst); 2007 Jan; 6(1):82-93. PubMed ID: 17049932
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Strand specificity and absence of hot spots for p53 mutations in ultraviolet B-induced skin tumors of XPA-deficient mice.
    Takeuchi S; Nakatsu Y; Nakane H; Murai H; Hirota S; Kitamura Y; Okuyama A; Tanaka K
    Cancer Res; 1998 Feb; 58(4):641-6. PubMed ID: 9485015
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A novel p53 mutational hotspot in skin tumors from UV-irradiated Xpc mutant mice alters transactivation functions.
    Inga A; Nahari D; Velasco-Miguel S; Friedberg EC; Resnick MA
    Oncogene; 2002 Aug; 21(37):5704-15. PubMed ID: 12173040
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Selective DNA damage responses in murine Xpa-/-, Xpc-/- and Csb-/- keratinocyte cultures.
    Stout GJ; Oosten Mv; Acherrat FZ; Wit Jd; Vermeij WP; Mullenders LH; Gruijl FR; Backendorf C
    DNA Repair (Amst); 2005 Nov; 4(11):1337-44. PubMed ID: 16182614
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mouse model for the DNA repair/basal transcription disorder trichothiodystrophy reveals cancer predisposition.
    de Boer J; van Steeg H; Berg RJ; Garssen J; de Wit J; van Oostrum CT; Beems RB; van der Horst GT; van Kreijl CF; de Gruijl FR; Bootsma D; Hoeijmakers JH; Weeda G
    Cancer Res; 1999 Jul; 59(14):3489-94. PubMed ID: 10416615
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Early p53-positive foci as indicators of tumor risk in ultraviolet-exposed hairless mice: kinetics of induction, effects of DNA repair deficiency, and p53 heterozygosity.
    Rebel H; Mosnier LO; Berg RJ; Westerman-de Vries A; van Steeg H; van Kranen HJ; de Gruijl FR
    Cancer Res; 2001 Feb; 61(3):977-83. PubMed ID: 11221893
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Genotype-specific Trp53 mutational analysis in ultraviolet B radiation-induced skin cancers in Xpc and Xpc Trp53 mutant mice.
    Reis AM; Cheo DL; Meira LB; Greenblatt MS; Bond JP; Nahari D; Friedberg EC
    Cancer Res; 2000 Mar; 60(6):1571-9. PubMed ID: 10749125
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Cell-type-specific consequences of nucleotide excision repair deficiencies: Embryonic stem cells versus fibroblasts.
    de Waard H; Sonneveld E; de Wit J; Esveldt-van Lange R; Hoeijmakers JH; Vrieling H; van der Horst GT
    DNA Repair (Amst); 2008 Oct; 7(10):1659-69. PubMed ID: 18634906
    [TBL] [Abstract][Full Text] [Related]  

  • 13. UV-induced DNA damage and mutations in Hupki (human p53 knock-in) mice recapitulate p53 hotspot alterations in sun-exposed human skin.
    Luo JL; Tong WM; Yoon JH; Hergenhahn M; Koomagi R; Yang Q; Galendo D; Pfeifer GP; Wang ZQ; Hollstein M
    Cancer Res; 2001 Nov; 61(22):8158-63. PubMed ID: 11719445
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Inverse relationship between increased apoptosis and decreased skin cancer in UV-irradiated CD1d-/- mice.
    Matsumura Y; Moodycliffe AM; Nghiem DX; Ullrich SE; Ananthaswamy HN
    Photochem Photobiol; 2005; 81(1):46-51. PubMed ID: 15496135
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mutation spectrum in UVB-exposed skin epidermis of Xpa-knockout mice: frequent recovery of triplet mutations.
    Ikehata H; Yanase F; Mori T; Nikaido O; Tanaka K; Ono T
    Environ Mol Mutagen; 2007 Jan; 48(1):1-13. PubMed ID: 17163503
    [TBL] [Abstract][Full Text] [Related]  

  • 16. p53 protects against skin cancer induction by UV-B radiation.
    Jiang W; Ananthaswamy HN; Muller HK; Kripke ML
    Oncogene; 1999 Jul; 18(29):4247-53. PubMed ID: 10435637
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Clones of normal keratinocytes and a variety of simultaneously present epidermal neoplastic lesions contain a multitude of p53 gene mutations in a xeroderma pigmentosum patient.
    Williams C; Pontén F; Ahmadian A; Ren ZP; Ling G; Rollman O; Ljung A; Jaspers NG; Uhlén M; Lundeberg J; Pontén J
    Cancer Res; 1998 Jun; 58(11):2449-55. PubMed ID: 9622088
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Impact of global genome repair versus transcription-coupled repair on ultraviolet carcinogenesis in hairless mice.
    Berg RJ; Rebel H; van der Horst GT; van Kranen HJ; Mullenders LH; van Vloten WA; de Gruijl FR
    Cancer Res; 2000 Jun; 60(11):2858-63. PubMed ID: 10850428
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Association between DNA repair-deficiency and high level of p53 mutations in melanoma of Xeroderma pigmentosum.
    Spatz A; Giglia-Mari G; Benhamou S; Sarasin A
    Cancer Res; 2001 Mar; 61(6):2480-6. PubMed ID: 11289118
    [TBL] [Abstract][Full Text] [Related]  

  • 20. p53 heterozygosity results in an increased 2-acetylaminofluorene-induced urinary bladder but not liver tumor response in DNA repair-deficient Xpa mice.
    Hoogervorst EM; van Oostrom CT; Beems RB; van Benthem J; Gielis S; Vermeulen JP; Wester PW; Vos JG; de Vries A; van Steeg H
    Cancer Res; 2004 Aug; 64(15):5118-26. PubMed ID: 15289314
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.