263 related articles for article (PubMed ID: 10604980)
1. Involvement of an organic anion transporter (canalicular multispecific organic anion transporter/multidrug resistance-associated protein 2) in gastrointestinal secretion of glutathione conjugates in rats.
Gotoh Y; Suzuki H; Kinoshita S; Hirohashi T; Kato Y; Sugiyama Y
J Pharmacol Exp Ther; 2000 Jan; 292(1):433-9. PubMed ID: 10604980
[TBL] [Abstract][Full Text] [Related]
2. Hepatic expression of multidrug resistance-associated protein-like proteins maintained in eisai hyperbilirubinemic rats.
Hirohashi T; Suzuki H; Ito K; Ogawa K; Kume K; Shimizu T; Sugiyama Y
Mol Pharmacol; 1998 Jun; 53(6):1068-75. PubMed ID: 9614210
[TBL] [Abstract][Full Text] [Related]
3. Kinetic analysis of the primary active transport of conjugated metabolites across the bile canalicular membrane: comparative study of S-(2,4-dinitrophenyl)-glutathione and 6-hydroxy-5,7-dimethyl-2-methylamino-4-(3-pyridylmethyl)benzothiazole glucuronide.
Niinuma K; Takenaka O; Horie T; Kobayashi K; Kato Y; Suzuki H; Sugiyama Y
J Pharmacol Exp Ther; 1997 Aug; 282(2):866-72. PubMed ID: 9262353
[TBL] [Abstract][Full Text] [Related]
4. Temocaprilat, a novel angiotensin-converting enzyme inhibitor, is excreted in bile via an ATP-dependent active transporter (cMOAT) that is deficient in Eisai hyperbilirubinemic mutant rats (EHBR).
Ishizuka H; Konno K; Naganuma H; Sasahara K; Kawahara Y; Niinuma K; Suzuki H; Sugiyama Y
J Pharmacol Exp Ther; 1997 Mar; 280(3):1304-11. PubMed ID: 9067317
[TBL] [Abstract][Full Text] [Related]
5. Both cMOAT/MRP2 and another unknown transporter(s) are responsible for the biliary excretion of glucuronide conjugate of the nonpeptide angiotensin II antagonist, telmisaltan.
Nishino A; Kato Y; Igarashi T; Sugiyama Y
Drug Metab Dispos; 2000 Oct; 28(10):1146-8. PubMed ID: 10997931
[TBL] [Abstract][Full Text] [Related]
6. Biliary excretion of 17beta-estradiol 17beta-D-glucuronide is predominantly mediated by cMOAT/MRP2.
Morikawa A; Goto Y; Suzuki H; Hirohashi T; Sugiyama Y
Pharm Res; 2000 May; 17(5):546-52. PubMed ID: 10888306
[TBL] [Abstract][Full Text] [Related]
7. [Analysis of xenobiotic detoxification system mediated by efflux transporters].
Suzuki H
Yakugaku Zasshi; 1999 Nov; 119(11):822-34. PubMed ID: 10590710
[TBL] [Abstract][Full Text] [Related]
8. Molecular cloning of canalicular multispecific organic anion transporter defective in EHBR.
Ito K; Suzuki H; Hirohashi T; Kume K; Shimizu T; Sugiyama Y
Am J Physiol; 1997 Jan; 272(1 Pt 1):G16-22. PubMed ID: 9038871
[TBL] [Abstract][Full Text] [Related]
9. Reduced folate derivatives are endogenous substrates for cMOAT in rats.
Kusuhara H; Han YH; Shimoda M; Kokue E; Suzuki H; Sugiyama Y
Am J Physiol; 1998 Oct; 275(4):G789-96. PubMed ID: 9756510
[TBL] [Abstract][Full Text] [Related]
10. Function and expression of multidrug resistance-associated protein family in human colon adenocarcinoma cells (Caco-2).
Hirohashi T; Suzuki H; Chu XY; Tamai I; Tsuji A; Sugiyama Y
J Pharmacol Exp Ther; 2000 Jan; 292(1):265-70. PubMed ID: 10604957
[TBL] [Abstract][Full Text] [Related]
11. Site-specific bidirectional efflux of 2,4-dinitrophenyl-S-glutathione, a substrate of multidrug resistance-associated proteins, in rat intestine and Caco-2 cells.
Yokooji T; Murakami T; Yumoto R; Nagai J; Takano M
J Pharm Pharmacol; 2007 Apr; 59(4):513-20. PubMed ID: 17430634
[TBL] [Abstract][Full Text] [Related]
12. Carrier-mediated mechanism for the biliary excretion of the quinolone antibiotic grepafloxacin and its glucuronide in rats.
Sasabe H; Tsuji A; Sugiyama Y
J Pharmacol Exp Ther; 1998 Mar; 284(3):1033-9. PubMed ID: 9495864
[TBL] [Abstract][Full Text] [Related]
13. Involvement of Mrp2 in hepatic and intestinal disposition of dinitrophenyl-S-glutathione in partially hepatectomized rats.
Villanueva SS; Ruiz ML; Luquita MG; Sánchez Pozzi EJ; Catania VA; Mottino AD
Toxicol Sci; 2005 Mar; 84(1):4-11. PubMed ID: 15590889
[TBL] [Abstract][Full Text] [Related]
14. Secretion of organic anions by hepatocytes: involvement of homologues of the multidrug resistance protein.
Müller M; Roelofsen H; Jansen PL
Semin Liver Dis; 1996 May; 16(2):211-20. PubMed ID: 8781025
[TBL] [Abstract][Full Text] [Related]
15. Multispecific organic anion transporter is responsible for the biliary excretion of the camptothecin derivative irinotecan and its metabolites in rats.
Chu XY; Kato Y; Niinuma K; Sudo KI; Hakusui H; Sugiyama Y
J Pharmacol Exp Ther; 1997 Apr; 281(1):304-14. PubMed ID: 9103511
[TBL] [Abstract][Full Text] [Related]
16. Modulation of intestinal transport of 2,4-dinitrophenyl-S-glutathione, a multidrug resistance-associated protein 2 substrate, by bilirubin treatment in rats.
Yokooji T; Murakami T; Ogawa K; Yumoto R; Nagai J; Takano M
J Pharm Pharmacol; 2005 May; 57(5):579-85. PubMed ID: 15901347
[TBL] [Abstract][Full Text] [Related]
17. Treatment of hyperbilirubinemia in Eisai hyperbilirubinemic rat by transfecting human MRP2/ABCC2 gene.
Hirouchi M; Suzuki H; Sugiyama Y
Pharm Res; 2005 Apr; 22(4):661-6. PubMed ID: 15846474
[TBL] [Abstract][Full Text] [Related]
18. Functional analysis of a canalicular multispecific organic anion transporter cloned from rat liver.
Ito K; Suzuki H; Hirohashi T; Kume K; Shimizu T; Sugiyama Y
J Biol Chem; 1998 Jan; 273(3):1684-8. PubMed ID: 9430713
[TBL] [Abstract][Full Text] [Related]
19. Increase in bile flow and biliary excretion of glutathione-derived sulfhydryls in rats by drug-metabolizing enzyme inducers is mediated by multidrug resistance protein 2.
Johnson DR; Habeebu SS; Klaassen CD
Toxicol Sci; 2002 Mar; 66(1):16-26. PubMed ID: 11861969
[TBL] [Abstract][Full Text] [Related]
20. Excretion of GSSG and glutathione conjugates mediated by MRP1 and cMOAT/MRP2.
Suzuki H; Sugiyama Y
Semin Liver Dis; 1998; 18(4):359-76. PubMed ID: 9875554
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
