105 related articles for article (PubMed ID: 10617082)
1. N'-[2-(2-thiophene)ethyl]-N'-[2-(5-bromopyridyl)] thiourea as a potent inhibitor of NNI-resistant and multidrug-resistant human immunodeficiency virus-1.
Uckun FM; Pendergrass S; Maher D; Zhu D; Tuel-Ahlgren L; Mao C; Venkatachalam TK
Bioorg Med Chem Lett; 1999 Dec; 9(24):3411-6. PubMed ID: 10617082
[TBL] [Abstract][Full Text] [Related]
2. N-[2-(1-cyclohexenyl)ethyl]-N'-[2-(5-bromopyridyl)]-thiourea and N'-[2-(1-cyclohexenyl)ethyl]-N'-[2-(5-chloropyridyl)]-thiourea as potent inhibitors of multidrug-resistant human immunodeficiency virus-1.
Uckun FM; Mao C; Pendergrass S; Maher D; Zhu D; Tuel-Ahlgren L; Venkatachalam TK
Bioorg Med Chem Lett; 1999 Sep; 9(18):2721-6. PubMed ID: 10509923
[TBL] [Abstract][Full Text] [Related]
3. Rational design of N-[2-(2,5-dimethoxyphenylethyl)]-N'-[2-(5-bromopyridyl)]-thiourea (HI-236) as a potent non-nucleoside inhibitor of drug-resistant human immunodeficiency virus.
Mao C; Sudbeck EA; Venkatachalam TK; Uckun FM
Bioorg Med Chem Lett; 1999 Jun; 9(11):1593-8. PubMed ID: 10386942
[TBL] [Abstract][Full Text] [Related]
4. Structure-based design of non-nucleoside reverse transcriptase inhibitors of drug-resistant human immunodeficiency virus.
Mao C; Sudbeck EA; Venkatachalam TK; Uckun FM
Antivir Chem Chemother; 1999 Sep; 10(5):233-40. PubMed ID: 10574178
[TBL] [Abstract][Full Text] [Related]
5. N-[2-(4-methylphenyl)ethyl]-N'-[2-(5-bromopyridyl)]-thiourea as a potent inhibitor of NNRTI-resistant and multidrug-resistant human immunodeficiency virus type 1.
Uckun FM; Mao C; Pendergrass S; Maher D; Zhu D; Tuel-Ahlgren L; Venkatachalam TK
Antivir Chem Chemother; 2000 Mar; 11(2):135-40. PubMed ID: 10819437
[TBL] [Abstract][Full Text] [Related]
6. Stereochemistry of halopyridyl and thiazolyl thiourea compounds is a major determinant of their potency as nonnucleoside inhibitors of HIV-1 reverse transcriptase.
Venkatachalam TK; Sudbeck EA; Mao C; Uckun FM
Bioorg Med Chem Lett; 2000 Sep; 10(18):2071-4. PubMed ID: 10999473
[TBL] [Abstract][Full Text] [Related]
7. Piperidinylethyl, phenoxyethyl and fluoroethyl bromopyridyl thiourea compounds with potent anti-HIV activity.
Venkatachalam TK; Sudbec EA; Mao C; Uckun FM
Antivir Chem Chemother; 2000 Sep; 11(5):329-36. PubMed ID: 11142631
[TBL] [Abstract][Full Text] [Related]
8. Stereochemistry as a major determinant of the anti-HIV activity of chiral naphthyl thiourea compounds.
Venkatachalam TK; Mao C; Uckun FM
Antivir Chem Chemother; 2001 Jul; 12(4):213-21. PubMed ID: 11771730
[TBL] [Abstract][Full Text] [Related]
9. Structure-based design of N-[2-(1-piperidinylethyl)]-N'-[2-(5-bromopyridyl)]-thiourea and N-[2-(1-piperazinylethyl)]-N'-[2-(5-bromopyridyl)]-thiourea as potent non-nucleoside inhibitors of HIV-1 reverse transcriptase.
Mao C; Vig R; Venkatachalam TK; Sudbeck EA; Uckun FM
Bioorg Med Chem Lett; 1998 Aug; 8(16):2213-8. PubMed ID: 9873515
[TBL] [Abstract][Full Text] [Related]
10. N'-[2-(2-thiophene) ethyl]-N'-[2-(5-bromopyridyl)]thiourea (HI-443), a rationally designed non-nucleoside reverse transcriptase inhibitor compound with potent anti-HIV activity.
Uckun FM; Qazi S; Venkatachalam T
Arzneimittelforschung; 2007; 57(5):278-85. PubMed ID: 17598700
[TBL] [Abstract][Full Text] [Related]
11. Novel derivatives of phenethyl-5-bromopyridylthiourea and dihydroalkoxybenzyloxopyrimidine are dual-function spermicides with potent anti-human immunodeficiency virus activity.
D'Cruz OJ; Uckun FM
Biol Reprod; 1999 Jun; 60(6):1419-28. PubMed ID: 10330101
[TBL] [Abstract][Full Text] [Related]
12. Structural requirements for potent anti-human immunodeficiency virus (HIV) and sperm-immobilizing activities of cyclohexenyl thiourea and urea non-nucleoside inhibitors of HIV-1 reverse transcriptase.
D'Cruz OJ; Venkatachalam TK; Mao C; Qazi S; Uckun FM
Biol Reprod; 2002 Dec; 67(6):1959-74. PubMed ID: 12444075
[TBL] [Abstract][Full Text] [Related]
13. Discovery of 2,5-dimethoxy-substituted 5-bromopyridyl thiourea (PHI-236) as a potent broad-spectrum anti-human immunodeficiency virus microbicide.
D'Cruz OJ; Uckun FM
Mol Hum Reprod; 2005 Oct; 11(10):767-77. PubMed ID: 16254003
[TBL] [Abstract][Full Text] [Related]
14. Potent dual anti-HIV and spermicidal activities of novel oxovanadium(V) complexes with thiourea non-nucleoside inhibitors of HIV-1 reverse transcriptase.
D'Cruz OJ; Dong Y; Uckun FM
Biochem Biophys Res Commun; 2003 Mar; 302(2):253-64. PubMed ID: 12604339
[TBL] [Abstract][Full Text] [Related]
15. A novel vaginal microbicide containing the rationally designed anti-HIV compound HI-443 (N'-[2-(2-thiophene)ethyl]-N'-[2-(5-bromopyridyl)] thiourea]).
D'Cruz OJ; Qazi S; Yiv S; Uckun FM
Expert Opin Investig Drugs; 2012 Mar; 21(3):265-79. PubMed ID: 22292483
[TBL] [Abstract][Full Text] [Related]
16. Large-scale synthesis of GMP grade N'- [2-(2-thiophene) ethyl]-N'- [2- (5-bromopyridyl)] -thiourea (HI-443), a new anti-HIV drug candidate.
DuMez D; Venkatachalam TK; Uckun FM
Arzneimittelforschung; 2007; 57(6):330-8. PubMed ID: 17688078
[TBL] [Abstract][Full Text] [Related]
17. Effect of stereochemistry on the anti-HIV activity of chiral thiourea compounds.
Venkatachalam TK; Mao C; Uckun FM
Bioorg Med Chem; 2004 Aug; 12(15):4275-84. PubMed ID: 15246104
[TBL] [Abstract][Full Text] [Related]
18. Novel thiourea compounds as dual-function microbicides.
D'Cruz OJ; Venkatachalam TK; Uckun FM
Biol Reprod; 2000 Jul; 63(1):196-205. PubMed ID: 10859260
[TBL] [Abstract][Full Text] [Related]
19. Anti-HIV activity of aromatic and heterocyclic thiazolyl thiourea compounds.
Venkatachalam TK; Sudbeck EA; Mao C; Uckun FM
Bioorg Med Chem Lett; 2001 Feb; 11(4):523-8. PubMed ID: 11229762
[TBL] [Abstract][Full Text] [Related]
20. A 13-week subchronic intravaginal toxicity study of the novel broad-spectrum anti-HIV and spermicidal agent, N-[2-(1-cyclohexenyl)ethyl]-N'-[2-(5-bromopyridyl)]-thiourea (PHI-346) in mice.
D'Cruz OJ; Waurzyniak B; Uckun FM
Toxicol Pathol; 2002; 30(6):687-95. PubMed ID: 12512870
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
