BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

185 related articles for article (PubMed ID: 10619355)

  • 1. Genomic structure of rat 3alpha-hydroxysteroid/dihydrodiol dehydrogenase (3alpha-HSD/DD, AKR1C9).
    Lin HK; Hung CF; Moore M; Penning TM
    J Steroid Biochem Mol Biol; 1999 Nov; 71(1-2):29-39. PubMed ID: 10619355
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Members of the nuclear factor 1 transcription factor family regulate rat 3alpha-hydroxysteroid/dihydrodiol dehydrogenase (3alpha-HSD/DD AKR1C9) gene expression: a member of the aldo-keto reductase superfamily.
    Hung CF; Penning TM
    Mol Endocrinol; 1999 Oct; 13(10):1704-17. PubMed ID: 10517672
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Cloning, sequencing, and functional analysis of the 5'-flanking region of the rat 3 alpha-hydroxysteroid/dihydrodiol dehydrogenase gene.
    Lin HK; Penning TM
    Cancer Res; 1995 Sep; 55(18):4105-13. PubMed ID: 7664287
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Human 3alpha-hydroxysteroid dehydrogenase isoforms (AKR1C1-AKR1C4) of the aldo-keto reductase superfamily: functional plasticity and tissue distribution reveals roles in the inactivation and formation of male and female sex hormones.
    Penning TM; Burczynski ME; Jez JM; Hung CF; Lin HK; Ma H; Moore M; Palackal N; Ratnam K
    Biochem J; 2000 Oct; 351(Pt 1):67-77. PubMed ID: 10998348
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Dexamethasone regulation of the rat 3alpha-hydroxysteroid/dihydrodiol dehydrogenase gene.
    Hou YT; Lin HK; Penning TM
    Mol Pharmacol; 1998 Mar; 53(3):459-66. PubMed ID: 9495812
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Close kinship of human 20alpha-hydroxysteroid dehydrogenase gene with three aldo-keto reductase genes.
    Nishizawa M; Nakajima T; Yasuda K; Kanzaki H; Sasaguri Y; Watanabe K; Ito S
    Genes Cells; 2000 Feb; 5(2):111-25. PubMed ID: 10672042
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structure-function aspects and inhibitor design of type 5 17beta-hydroxysteroid dehydrogenase (AKR1C3).
    Penning TM; Burczynski ME; Jez JM; Lin HK; Ma H; Moore M; Ratnam K; Palackal N
    Mol Cell Endocrinol; 2001 Jan; 171(1-2):137-49. PubMed ID: 11165022
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Structure-function relationships in 3alpha-hydroxysteroid dehydrogenases: a comparison of the rat and human isoforms.
    Penning TM; Jin Y; Heredia VV; Lewis M
    J Steroid Biochem Mol Biol; 2003 Jun; 85(2-5):247-55. PubMed ID: 12943710
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Structure-function of human 3 alpha-hydroxysteroid dehydrogenases: genes and proteins.
    Penning TM; Jin Y; Steckelbroeck S; Lanisnik Rizner T; Lewis M
    Mol Cell Endocrinol; 2004 Feb; 215(1-2):63-72. PubMed ID: 15026176
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Androgen inactivation and steroid-converting enzyme expression in abdominal adipose tissue in men.
    Blouin K; Richard C; Brochu G; Hould FS; Lebel S; Marceau S; Biron S; Luu-The V; Tchernof A
    J Endocrinol; 2006 Dec; 191(3):637-49. PubMed ID: 17170221
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Examination of the differences in structure-function of human and rat 3alpha-hydroxysteroid dehydrogenase.
    Jin Y; Cooper WC; Penning TM
    Chem Biol Interact; 2003 Feb; 143-144():383-92. PubMed ID: 12604225
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Stable expression of rat dihydrodiol dehydrogenase (AKR1C9) in human breast MCF-7 cells results in the formation of PAH-o-quinones and enzyme mediated cell death.
    Tsuruda L; Hou Yt ; Penning TM
    Chem Res Toxicol; 2001 Jul; 14(7):856-62. PubMed ID: 11453732
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Cloning of the human RoDH-related short chain dehydrogenase gene and analysis of its structure.
    Kedishvili NY; Belyaeva OV; Gough WH
    Chem Biol Interact; 2001 Jan; 130-132(1-3):457-67. PubMed ID: 11306067
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Expression and characterization of recombinant type 2 3 alpha-hydroxysteroid dehydrogenase (HSD) from human prostate: demonstration of bifunctional 3 alpha/17 beta-HSD activity and cellular distribution.
    Lin HK; Jez JM; Schlegel BP; Peehl DM; Pachter JA; Penning TM
    Mol Endocrinol; 1997 Dec; 11(13):1971-84. PubMed ID: 9415401
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Steroid-binding site residues dictate optimal substrate positioning in rat 3alpha-hydroxysteroid dehydrogenase (3alpha-HSD or AKR1C9).
    Heredia VV; Kruger RG; Penning TM
    Chem Biol Interact; 2003 Feb; 143-144():393-400. PubMed ID: 12604226
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Tibolone metabolism in human liver is catalyzed by 3alpha/3beta-hydroxysteroid dehydrogenase activities of the four isoforms of the aldo-keto reductase (AKR)1C subfamily.
    Steckelbroeck S; Oyesanmi B; Jin Y; Lee SH; Kloosterboer HJ; Penning TM
    J Pharmacol Exp Ther; 2006 Mar; 316(3):1300-9. PubMed ID: 16339391
    [TBL] [Abstract][Full Text] [Related]  

  • 17. 3 alpha-hydroxysteroid dehydrogenase: three dimensional structure and gene regulation.
    Penning TM
    J Endocrinol; 1996 Sep; 150 Suppl():S175-87. PubMed ID: 8943801
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Conversion of mammalian 3alpha-hydroxysteroid dehydrogenase to 20alpha-hydroxysteroid dehydrogenase using loop chimeras: changing specificity from androgens to progestins.
    Ma H; Penning TM
    Proc Natl Acad Sci U S A; 1999 Sep; 96(20):11161-6. PubMed ID: 10500147
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Overexpression and mutagenesis of the cDNA for rat liver 3 alpha-hydroxysteroid/dihydrodiol dehydrogenase. Role of cysteines and tyrosines in catalysis.
    Pawlowski JE; Penning TM
    J Biol Chem; 1994 May; 269(18):13502-10. PubMed ID: 8175784
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Molecular determinants of steroid recognition and catalysis in aldo-keto reductases. Lessons from 3alpha-hydroxysteroid dehydrogenase.
    Penning TM
    J Steroid Biochem Mol Biol; 1999; 69(1-6):211-25. PubMed ID: 10418995
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.