148 related articles for article (PubMed ID: 10623624)
1. Synthesis and biochemical evaluation of novel inhibitors of aromatase (AR) using an enhanced representation of the active site of AR derived from the consideration of the reaction mechanism.
Ahmed S; Amanuel Y
Biochem Biophys Res Commun; 2000 Jan; 267(1):356-61. PubMed ID: 10623624
[TBL] [Abstract][Full Text] [Related]
2. Molecular modelling study of the binding of inhibitors of aromatase to the cytochrome P-450 heme.
Ahmed S; Davis PJ; Owen CP
Drug Des Discov; 1996 Oct; 14(2):91-102. PubMed ID: 9010616
[TBL] [Abstract][Full Text] [Related]
3. Novel oxazolidinone based compounds as inhibitors of aromatase and the use of the substrate-heme complex approach in the rationalisation of these compounds.
Ahmed S; Adat S; Murrells A; Owen CP
Biochem Biophys Res Commun; 2002 Jun; 294(2):380-3. PubMed ID: 12051723
[TBL] [Abstract][Full Text] [Related]
4. Molecular modelling study of pyrrolidine-2,5-dione based aromatase inhibitors and other known inhibitors.
Ahmed S
Drug Des Discov; 1996 Mar; 14(1):77-89. PubMed ID: 8854046
[TBL] [Abstract][Full Text] [Related]
5. Pharmacology of aminoglutethimide: structure/activity relationships and receptor interactions.
Nicholls PJ; Daly MJ; Smith HJ
Breast Cancer Res Treat; 1986; 7 Suppl():S55-67. PubMed ID: 3755630
[TBL] [Abstract][Full Text] [Related]
6. Binding characteristics of aromatase inhibitors and phytoestrogens to human aromatase.
Chen S; Kao YC; Laughton CA
J Steroid Biochem Mol Biol; 1997 Apr; 61(3-6):107-15. PubMed ID: 9365179
[TBL] [Abstract][Full Text] [Related]
7. Synthesis and structure-activity relationships of 6-substituted androst-4-ene analogs as aromatase inhibitors.
Numazawa M; Kamiyama T; Tachibana M; Oshibe M
J Med Chem; 1996 May; 39(11):2245-52. PubMed ID: 8667367
[TBL] [Abstract][Full Text] [Related]
8. Structure-activity relationships of new A,D-ring modified steroids as aromatase inhibitors: design, synthesis, and biological activity evaluation.
Cepa MM; Tavares da Silva EJ; Correia-da-Silva G; Roleira FM; Teixeira NA
J Med Chem; 2005 Oct; 48(20):6379-85. PubMed ID: 16190763
[TBL] [Abstract][Full Text] [Related]
9. Synthesis and biological evaluation of imidazole based compounds as cytochrome P-450 inhibitors.
Ahmed S; Smith JH; Nicholls PJ; Whomsley R; Cariuk P
Drug Des Discov; 1995 Aug; 13(1):27-41. PubMed ID: 8882899
[TBL] [Abstract][Full Text] [Related]
10. Synthesis and aromatase inhibiting activity of aminoglutethimide analogs.
Aboul-Enein HY
Drug Des Deliv; 1988 Feb; 2(3):221-6. PubMed ID: 3255316
[TBL] [Abstract][Full Text] [Related]
11. In vitro inhibition of aromatase by the enantiomers of aminoglutethimide and analogs.
Ogbunude PO; Aboul-Enein HY
Chirality; 1994; 6(8):623-6. PubMed ID: 7857773
[TBL] [Abstract][Full Text] [Related]
12. Aromatase inhibition by an 11,13-dihydroderivative of a sesquiterpene lactone.
Blanco JG; Gil RR; Bocco JL; Meragelman TL; Genti-Raimondi S; Flury A
J Pharmacol Exp Ther; 2001 Jun; 297(3):1099-105. PubMed ID: 11356934
[TBL] [Abstract][Full Text] [Related]
13. The use of the substrate-heme complex approach in the design, synthesis, biochemical evaluation, and rationalization of the inhibitory activity of a range of azole compounds against cholesterol side chain cleavage enzyme.
Ahmed S
Biochem Biophys Res Commun; 2000 Aug; 275(1):75-6. PubMed ID: 10944444
[TBL] [Abstract][Full Text] [Related]
14. Synthesis and characterization of azole isoflavone inhibitors of aromatase.
Hackett JC; Kim YW; Su B; Brueggemeier RW
Bioorg Med Chem; 2005 Jun; 13(12):4063-70. PubMed ID: 15911319
[TBL] [Abstract][Full Text] [Related]
15. Synthesis and biochemical studies of 17-substituted androst-3-enes and 3,4-epoxyandrostanes as aromatase inhibitors.
Cepa MM; Tavares da Silva EJ; Correia-da-Silva G; Roleira FM; Teixeira NA
Steroids; 2008 Dec; 73(14):1409-15. PubMed ID: 18691607
[TBL] [Abstract][Full Text] [Related]
16. Dual aromatase-sulfatase inhibitors based on the anastrozole template: synthesis, in vitro SAR, molecular modelling and in vivo activity.
Jackson T; Woo LW; Trusselle MN; Chander SK; Purohit A; Reed MJ; Potter BV
Org Biomol Chem; 2007 Sep; 5(18):2940-52. PubMed ID: 17728860
[TBL] [Abstract][Full Text] [Related]
17. Design, synthesis, and evaluation of 4-(4'-aminobenzyl)-2-oxazolidinones as novel inhibitors of the cytochrome P-450 enzyme aromatase.
Ahmed S; Adat S; Murrells A; Owen CP; Amanuel Y
Bioorg Chem; 2002 Oct; 30(5):315-31. PubMed ID: 12485592
[TBL] [Abstract][Full Text] [Related]
18. Overview of recent development of aromatase inhibitors.
Brodie AM
Cancer Res; 1982 Aug; 42(8 Suppl):3312s-3314s. PubMed ID: 7083192
[TBL] [Abstract][Full Text] [Related]
19. Aromatase reaction of 3-deoxyandrogens: steric mode of the C-19 oxygenation and cleavage of the C10-C19 bond by human placental aromatase.
Numazawa M; Nagaoka M; Sohtome N
Biochemistry; 2005 Aug; 44(32):10839-45. PubMed ID: 16086586
[TBL] [Abstract][Full Text] [Related]
20. Review of the molecular modelling studies of the cytochrome P-450 estrogen synthetase enzyme, aromatase.
Ahmed S
Drug Des Discov; 1998 Oct; 15(4):239-52. PubMed ID: 10546069
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
