BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

98 related articles for article (PubMed ID: 10623893)

  • 1. Cleavage and inactivation of antiapoptotic Akt/PKB by caspases during apoptosis.
    Rokudai S; Fujita N; Hashimoto Y; Tsuruo T
    J Cell Physiol; 2000 Feb; 182(2):290-6. PubMed ID: 10623893
    [TBL] [Abstract][Full Text] [Related]  

  • 2. XIAP regulates Akt activity and caspase-3-dependent cleavage during cisplatin-induced apoptosis in human ovarian epithelial cancer cells.
    Asselin E; Mills GB; Tsang BK
    Cancer Res; 2001 Mar; 61(5):1862-8. PubMed ID: 11280739
    [TBL] [Abstract][Full Text] [Related]  

  • 3. MEKK1-induced apoptosis requires TRAIL death receptor activation and is inhibited by AKT/PKB through inhibition of MEKK1 cleavage.
    Bild AH; Mendoza FJ; Gibson EM; Huang M; Villanueva J; Garrington TP; Jove R; Johnson GL; Gibson SB
    Oncogene; 2002 Sep; 21(43):6649-56. PubMed ID: 12242663
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Galectin-3 inhibits tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by activating Akt in human bladder carcinoma cells.
    Oka N; Nakahara S; Takenaka Y; Fukumori T; Hogan V; Kanayama HO; Yanagawa T; Raz A
    Cancer Res; 2005 Sep; 65(17):7546-53. PubMed ID: 16140916
    [TBL] [Abstract][Full Text] [Related]  

  • 5. IFN-gamma enhances paclitaxel-induced apoptosis that is modulated by activation of caspases 8 and 3 with a concomitant down regulation of the AKT survival pathway in cultured human keratinocytes.
    Hokeness K; Qiu LH; Vezeridis M; Yan BF; Mehta S; Wan YS
    Oncol Rep; 2005 May; 13(5):965-9. PubMed ID: 15809765
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Phosphatidylinositol 3-kinase (PI-3K)/Akt but not PI-3K/p70 S6 kinase signaling mediates IGF-1-promoted lens epithelial cell survival.
    Chandrasekher G; Sailaja D
    Invest Ophthalmol Vis Sci; 2004 Oct; 45(10):3577-88. PubMed ID: 15452065
    [TBL] [Abstract][Full Text] [Related]  

  • 7. SHP-2 regulates the phosphatidylinositide 3'-kinase/Akt pathway and suppresses caspase 3-mediated apoptosis.
    Ivins Zito C; Kontaridis MI; Fornaro M; Feng GS; Bennett AM
    J Cell Physiol; 2004 May; 199(2):227-36. PubMed ID: 15040005
    [TBL] [Abstract][Full Text] [Related]  

  • 8. PAK2 is cleaved and activated during hyperosmotic shock-induced apoptosis via a caspase-dependent mechanism: evidence for the involvement of oxidative stress.
    Chan WH; Yu JS; Yang SD
    J Cell Physiol; 1999 Mar; 178(3):397-408. PubMed ID: 9989786
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Overexpression of Akt (protein kinase B) confers protection against apoptosis and prevents formation of ceramide in response to pro-apoptotic stimuli.
    Goswami R; Kilkus J; Dawson SA; Dawson G
    J Neurosci Res; 1999 Sep; 57(6):884-93. PubMed ID: 10467260
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Molecular mechanisms of curcumin-induced cytotoxicity: induction of apoptosis through generation of reactive oxygen species, down-regulation of Bcl-XL and IAP, the release of cytochrome c and inhibition of Akt.
    Woo JH; Kim YH; Choi YJ; Kim DG; Lee KS; Bae JH; Min DS; Chang JS; Jeong YJ; Lee YH; Park JW; Kwon TK
    Carcinogenesis; 2003 Jul; 24(7):1199-208. PubMed ID: 12807727
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Acceleration of apoptotic cell death after the cleavage of Bcl-XL protein by caspase-3-like proteases.
    Fujita N; Nagahashi A; Nagashima K; Rokudai S; Tsuruo T
    Oncogene; 1998 Sep; 17(10):1295-304. PubMed ID: 9771973
    [TBL] [Abstract][Full Text] [Related]  

  • 12. IL-7 inhibits dexamethasone-induced apoptosis via Akt/PKB in mature, peripheral T cells.
    Sade H; Sarin A
    Eur J Immunol; 2003 Apr; 33(4):913-9. PubMed ID: 12672057
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The protein kinase PKB/Akt regulates cell survival and apoptosis by inhibiting Bax conformational change.
    Yamaguchi H; Wang HG
    Oncogene; 2001 Nov; 20(53):7779-86. PubMed ID: 11753656
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Inhibition of heat shock protein 90 function by 17-allylamino-17-demethoxy-geldanamycin in Hodgkin's lymphoma cells down-regulates Akt kinase, dephosphorylates extracellular signal-regulated kinase, and induces cell cycle arrest and cell death.
    Georgakis GV; Li Y; Rassidakis GZ; Martinez-Valdez H; Medeiros LJ; Younes A
    Clin Cancer Res; 2006 Jan; 12(2):584-90. PubMed ID: 16428504
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Growth factor-independent activation of protein kinase B contributes to the inherent resistance of vascular endothelium to radiation-induced apoptotic response.
    Tan J; Hallahan DE
    Cancer Res; 2003 Nov; 63(22):7663-7. PubMed ID: 14633687
    [TBL] [Abstract][Full Text] [Related]  

  • 16. IC101 induces apoptosis by Akt dephosphorylation via an inhibition of heat shock protein 90-ATP binding activity accompanied by preventing the interaction with Akt in L1210 cells.
    Fujiwara H; Yamakuni T; Ueno M; Ishizuka M; Shinkawa T; Isobe T; Ohizumi Y
    J Pharmacol Exp Ther; 2004 Sep; 310(3):1288-95. PubMed ID: 15161934
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Chronically elevated glucose-induced apoptosis is mediated by inactivation of Akt in cultured Müller cells.
    Xi X; Gao L; Hatala DA; Smith DG; Codispoti MC; Gong B; Kern TS; Zhang JZ
    Biochem Biophys Res Commun; 2005 Jan; 326(3):548-53. PubMed ID: 15596134
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Activation of Akt kinase inhibits apoptosis and changes in Bcl-2 and Bax expression induced by nitric oxide in primary hippocampal neurons.
    Matsuzaki H; Tamatani M; Mitsuda N; Namikawa K; Kiyama H; Miyake S; Tohyama M
    J Neurochem; 1999 Nov; 73(5):2037-46. PubMed ID: 10537063
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Opposite effects of Ha-Ras and Ki-Ras on radiation-induced apoptosis via differential activation of PI3K/Akt and Rac/p38 mitogen-activated protein kinase signaling pathways.
    Choi JA; Park MT; Kang CM; Um HD; Bae S; Lee KH; Kim TH; Kim JH; Cho CK; Lee YS; Chung HY; Lee SJ
    Oncogene; 2004 Jan; 23(1):9-20. PubMed ID: 14712206
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Antiapoptotic signaling in LNCaP prostate cancer cells: a survival signaling pathway independent of phosphatidylinositol 3'-kinase and Akt/protein kinase B.
    Carson JP; Kulik G; Weber MJ
    Cancer Res; 1999 Apr; 59(7):1449-53. PubMed ID: 10197612
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.