BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

270 related articles for article (PubMed ID: 10627458)

  • 1. The residual megakaryocyte and platelet production in c-mpl-deficient mice is not dependent on the actions of interleukin-6, interleukin-11, or leukemia inhibitory factor.
    Gainsford T; Nandurkar H; Metcalf D; Robb L; Begley CG; Alexander WS
    Blood; 2000 Jan; 95(2):528-34. PubMed ID: 10627458
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Thrombopoietin signaling is required for in vivo expansion of IL-11--responsive hematopoietic progenitor cells in the steady state.
    Scott CL; Robb L; Nandurkar HH; Mansfield R; Alexander WS; Begley CG
    Exp Hematol; 2001 Feb; 29(2):138-45. PubMed ID: 11166452
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Cytokine production and function in c-mpl-deficient mice: no physiologic role for interleukin-3 in residual megakaryocyte and platelet production.
    Gainsford T; Roberts AW; Kimura S; Metcalf D; Dranoff G; Mulligan RC; Begley CG; Robb L; Alexander WS
    Blood; 1998 Apr; 91(8):2745-52. PubMed ID: 9531584
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Low levels of erythroid and myeloid progenitors in thrombopoietin-and c-mpl-deficient mice.
    Carver-Moore K; Broxmeyer HE; Luoh SM; Cooper S; Peng J; Burstein SA; Moore MW; de Sauvage FJ
    Blood; 1996 Aug; 88(3):803-8. PubMed ID: 8704234
    [TBL] [Abstract][Full Text] [Related]  

  • 5. IL-3 does not contribute to platelet production in c-Mpl-deficient mice.
    Chen Q; Solar G; Eaton DL; de Sauvage FJ
    Stem Cells; 1998; 16 Suppl 2():31-6. PubMed ID: 11012175
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Thrombopoietin stimulates colony-forming unit-megakaryocyte proliferation and megakaryocyte maturation independently of cytokines that signal through the gp130 receptor subunit.
    Broudy VC; Lin NL; Fox N; Taga T; Saito M; Kaushansky K
    Blood; 1996 Sep; 88(6):2026-32. PubMed ID: 8822921
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Deficiencies in progenitor cells of multiple hematopoietic lineages and defective megakaryocytopoiesis in mice lacking the thrombopoietic receptor c-Mpl.
    Alexander WS; Roberts AW; Nicola NA; Li R; Metcalf D
    Blood; 1996 Mar; 87(6):2162-70. PubMed ID: 8630375
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Normal platelets and megakaryocytes are produced in vivo in the absence of thrombopoietin.
    Bunting S; Widmer R; Lipari T; Rangell L; Steinmetz H; Carver-Moore K; Moore MW; Keller GA; de Sauvage FJ
    Blood; 1997 Nov; 90(9):3423-9. PubMed ID: 9345025
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Thrombopoietin and the c-Mpl receptor: insights from gene targeting.
    Alexander WS
    Int J Biochem Cell Biol; 1999 Oct; 31(10):1027-35. PubMed ID: 10582337
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Thrombocytopenia in c-mpl-deficient mice.
    Gurney AL; Carver-Moore K; de Sauvage FJ; Moore MW
    Science; 1994 Sep; 265(5177):1445-7. PubMed ID: 8073287
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Promegapoietin, a family of chimeric growth factors, supports megakaryocyte development through activation of IL-3 and c-Mpl ligand signaling pathways.
    Doshi PD; Giri JG; Abegg AL; Favara JP; Huynh MS; Kahn LE; Minnerly JC; Pegg LE; Villani-Price D; Siegel NR; Staten NR; Thomas JW; McKearn JP; Smith WG
    Exp Hematol; 2001 Oct; 29(10):1177-84. PubMed ID: 11602319
    [TBL] [Abstract][Full Text] [Related]  

  • 12. c-mpl, the thrombopoietin receptor.
    Vainchenker W; Methia N; Debili N; Titeux M; Wendling F
    Thromb Haemost; 1995 Jul; 74(1):526-8. PubMed ID: 8578519
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Studies of the c-Mpl thrombopoietin receptor through gene disruption and activation.
    Alexander WS; Roberts AW; Maurer AB; Nicola NA; Dunn AR; Metcalf D
    Stem Cells; 1996; 14 Suppl 1():124-32. PubMed ID: 11012212
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Hematopoietic deficiencies in c-mpl and TPO knockout mice.
    Murone M; Carpenter DA; de Sauvage FJ
    Stem Cells; 1998; 16(1):1-6. PubMed ID: 9474742
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Role of the distal half of the c-Mpl intracellular domain in control of platelet production by thrombopoietin in vivo.
    Luoh SM; Stefanich E; Solar G; Steinmetz H; Lipari T; Pestina TI; Jackson CW; de Sauvage FJ
    Mol Cell Biol; 2000 Jan; 20(2):507-15. PubMed ID: 10611229
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Hematopoietic stem cell deficiencies in mice lacking c-Mpl, the receptor for thrombopoietin.
    Kimura S; Roberts AW; Metcalf D; Alexander WS
    Proc Natl Acad Sci U S A; 1998 Feb; 95(3):1195-200. PubMed ID: 9448308
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Lnk inhibits Tpo-mpl signaling and Tpo-mediated megakaryocytopoiesis.
    Tong W; Lodish HF
    J Exp Med; 2004 Sep; 200(5):569-80. PubMed ID: 15337790
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Thrombopoietin, but not cytokines binding to gp130 protein-coupled receptors, activates MAPKp42/44, AKT, and STAT proteins in normal human CD34+ cells, megakaryocytes, and platelets.
    Majka M; Ratajczak J; Villaire G; Kubiczek K; Marquez LA; Janowska-Wieczorek A; Ratajczak MZ
    Exp Hematol; 2002 Jul; 30(7):751-60. PubMed ID: 12135673
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Thrombopoietin does not induce lineage-restricted commitment of Mpl-R expressing pluripotent progenitors but permits their complete erythroid and megakaryocytic differentiation.
    Goncalves F; Lacout C; Villeval JL; Wendling F; Vainchenker W; Dumenil D
    Blood; 1997 May; 89(10):3544-53. PubMed ID: 9160659
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Thrombocytopenic c-mpl(-/-) mice can produce a normal level of platelets after administration of 5-fluorouracil: the effect of age on the response.
    Levin J; Cocault L; Demerens C; Challier C; Pauchard M; Caen J; Souyri M
    Blood; 2001 Aug; 98(4):1019-27. PubMed ID: 11493447
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.