These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

171 related articles for article (PubMed ID: 10639754)

  • 1. Inhibitory potency of 5-benzyluracil, 5-phenylcytosine and 5-phenylpyrimidin-2-one nucleosides against uridine phosphorylase from mouse leukemic L1210 cells.
    Votruba I; Krecmerová M; Hrebabecký H; Holý A
    Nucleosides Nucleotides; 1999; 18(11-12):2551-64. PubMed ID: 10639754
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Nucleosides and nucleotides. 175. Structural requirements of the sugar moiety for the antitumor activities of new nucleoside antimetabolites, 1-(3-C-ethynyl-beta-D-ribo-pentofuranosyl)cytosine and -uracil1.
    Hattori H; Nozawa E; Iino T; Yoshimura Y; Shuto S; Shimamoto Y; Nomura M; Fukushima M; Tanaka M; Sasaki T; Matsuda A
    J Med Chem; 1998 Jul; 41(15):2892-902. PubMed ID: 9667977
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis and evaluation of 6-methylene-bridged uracil derivatives. Part 2: optimization of inhibitors of human thymidine phosphorylase and their selectivity with uridine phosphorylase.
    Yano S; Kazuno H; Sato T; Suzuki N; Emura T; Wierzba K; Yamashita J; Tada Y; Yamada Y; Fukushima M; Asao T
    Bioorg Med Chem; 2004 Jul; 12(13):3443-50. PubMed ID: 15186830
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Nucleosides and nucleotides. 158. 1-(3-C-ethynyl-beta-D-ribo-pentofuranosyl)-cytosine, 1-(3-C-ethynyl-beta-D-ribo-pentofuranosyl)uracil, and their nucleobase analogues as new potential multifunctional antitumor nucleosides with a broad spectrum of activity.
    Hattori H; Tanaka M; Fukushima M; Sasaki T; Matsuda A
    J Med Chem; 1996 Dec; 39(25):5005-11. PubMed ID: 8960561
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis of 6-aminouracils and pyrrolo[2,3-d]pyrimidine-2,4-diones and their inhibitory effect on thymidine phosphorylase.
    Hirota K; Sawada M; Sajiki H; Sako M
    Nucleic Acids Symp Ser; 1997; (37):59-60. PubMed ID: 9585998
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Inhibition of uridine phosphorylase. Synthesis and structure-activity relationships of aryl-substituted 1-((2-hydroxyethoxy)methyl)-5-(3-phenoxybenzyl)uracil.
    Orr GF; Musso DL; Kelley JL; Joyner SS; Davis ST; Baccanari DP
    J Med Chem; 1997 Apr; 40(8):1179-85. PubMed ID: 9111291
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Design and synthesis of novel 5,6-disubstituted uracil derivatives as potent inhibitors of thymidine phosphorylase.
    Nencka R; Votruba I; Hrebabecký H; Tloust'ová E; Horská K; Masojídková M; Holý A
    Bioorg Med Chem Lett; 2006 Mar; 16(5):1335-7. PubMed ID: 16337119
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis and biological evaluation of unsaturated keto and exomethylene D-arabinopyranonucleoside analogs: novel 5-fluorouracil analogs that target thymidylate synthase.
    Tzioumaki N; Manta S; Tsoukala E; Vande Voorde J; Liekens S; Komiotis D; Balzarini J
    Eur J Med Chem; 2011 Apr; 46(4):993-1005. PubMed ID: 21330014
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inhibition of uridine phosphorylase: synthesis and structure-activity relationships of aryl-substituted 5-benzyluracils and 1-[(2-hydroxyethoxy)methyl]-5-benzyluracils.
    Orr GF; Musso DL; Boswell GE; Kelley JL; Joyner SS; Davis ST; Baccanari DP
    J Med Chem; 1995 Sep; 38(19):3850-6. PubMed ID: 7562916
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Nucleosides and nucleotides. 180. Synthesis and antitumor activity of nucleosides that have a hydroxylamino group instead of a hydroxyl group at the 2'- or 3'-position of the sugar moiety.
    Ogawa A; Tanaka M; Sasaki T; Matsuda A
    J Med Chem; 1998 Dec; 41(25):5094-107. PubMed ID: 9836625
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis and evaluation of 6-methylene-bridged uracil derivatives. Part 1: discovery of novel orally active inhibitors of human thymidine phosphorylase.
    Yano S; Kazuno H; Suzuki N; Emura T; Wierzba K; Yamashita J; Tada Y; Yamada Y; Fukushima M; Asao T
    Bioorg Med Chem; 2004 Jul; 12(13):3431-41. PubMed ID: 15186829
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis of 1-[[2-hydroxy-1-(hydroxymethyl)ethoxy] methyl]-5-benzyluracil and its amino analogue, new potent uridine phosphorylase inhibitors with high water solubility.
    Lin TS; Liu MC
    J Med Chem; 1985 Jul; 28(7):971-3. PubMed ID: 4009620
    [TBL] [Abstract][Full Text] [Related]  

  • 13. 5-benzylacyclouridine and 5-benzyloxybenzylacyclouridine, potent inhibitors of uridine phosphorylase.
    Niedzwicki JG; Chu SH; el Kouni MH; Rowe EC; Cha S
    Biochem Pharmacol; 1982 May; 31(10):1857-61. PubMed ID: 7104017
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis of 4,6-dideoxy-3-fluoro-2-keto-beta-D-glucopyranosyl analogues of 5-fluorouracil, N6-benzoyl adenine, uracil, thymine, N4-benzoyl cytosine and evaluation of their antitumor activities.
    Manta S; Tsoukala E; Tzioumaki N; Kiritsis C; Balzarini J; Komiotis D
    Bioorg Chem; 2010 Apr; 38(2):48-55. PubMed ID: 20018340
    [TBL] [Abstract][Full Text] [Related]  

  • 15. [Search for antimetabolites among 5-trimethylsilyluracil nucleosides and their nonglycoside analogs].
    Mel'nik SIa; Bakhmedova AA; Iartseva IV; Preobrazhenskaia MN; Zaguliaeva OA; Mamaev VP
    Bioorg Khim; 1991 Nov; 17(11):1526-33. PubMed ID: 1667356
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Michael addition reactions of some nucleobases to 1-(4,6-O-benzylidene-2,3-didehydro-2,3-dideoxy-3-nitro-beta-D- hexopyran osyl) uracil.
    Hibino H; Minamoto K; Suzuki S; Ukai T
    Nucleic Acids Symp Ser; 1997; (37):41-2. PubMed ID: 9585989
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Inhibitor properties of some 5-substituted uracil acyclonucleosides, and 2,2'-anhydrouridines versus uridine phosphorylase from E. coli and mammalian sources.
    Drabikowska AK; Lissowska L; Veres Z; Shugar D
    Biochem Pharmacol; 1987 Dec; 36(23):4125-8. PubMed ID: 3318842
    [TBL] [Abstract][Full Text] [Related]  

  • 18. [Polymethylene derivatives of nucleic bases with omega-functional groups. Pyrimidine derivatives].
    Makinskiĭ AA; Kritsyn AM; Ul'ianova EA; Zakharova OD; Nevinskiĭ GA
    Bioorg Khim; 2000 Oct; 26(10):735-42. PubMed ID: 11221254
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthesis, structure, and biological activity of certain 2-deoxy-beta-D-ribo-hexopyranosyl nucleosides and nucleotides.
    Nord LD; Dalley NK; McKernan PA; Robins RK
    J Med Chem; 1987 Jun; 30(6):1044-54. PubMed ID: 3585903
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structure-activity relationships of L-dioxolane uracil nucleosides as anti-Epstein Barr virus agents.
    Lin JS; Kira T; Gullen E; Choi Y; Qu F; Chu CK; Cheng YC
    J Med Chem; 1999 Jun; 42(12):2212-7. PubMed ID: 10377226
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.