BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

158 related articles for article (PubMed ID: 10646125)

  • 1. Expression of FGFR3 with the G380R achondroplasia mutation inhibits proliferation and maturation of CFK2 chondrocytic cells.
    Henderson JE; Naski MC; Aarts MM; Wang D; Cheng L; Goltzman D; Ornitz DM
    J Bone Miner Res; 2000 Jan; 15(1):155-65. PubMed ID: 10646125
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Insulin-like growth factor-1 rescues the mutated FGF receptor 3 (G380R) expressing ATDC5 cells from apoptosis through phosphatidylinositol 3-kinase and MAPK.
    Koike M; Yamanaka Y; Inoue M; Tanaka H; Nishimura R; Seino Y
    J Bone Miner Res; 2003 Nov; 18(11):2043-51. PubMed ID: 14606518
    [TBL] [Abstract][Full Text] [Related]  

  • 3. PTHrP rescues ATDC5 cells from apoptosis induced by FGF receptor 3 mutation.
    Yamanaka Y; Tanaka H; Koike M; Nishimura R; Seino Y
    J Bone Miner Res; 2003 Aug; 18(8):1395-403. PubMed ID: 12929929
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Graded activation of fibroblast growth factor receptor 3 by mutations causing achondroplasia and thanatophoric dysplasia.
    Naski MC; Wang Q; Xu J; Ornitz DM
    Nat Genet; 1996 Jun; 13(2):233-7. PubMed ID: 8640234
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Expression of fibroblast growth factor receptor 3 by fibroblast growth factor 2 in cultured chick embryo chondrocytes.
    Suh JY; Kim YS; Park JW; Sonn JK; Kim WT
    Cell Biol Int; 2005 Mar; 29(3):203-12. PubMed ID: 15878293
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Constitutive activation of MEK1 in chondrocytes causes Stat1-independent achondroplasia-like dwarfism and rescues the Fgfr3-deficient mouse phenotype.
    Murakami S; Balmes G; McKinney S; Zhang Z; Givol D; de Crombrugghe B
    Genes Dev; 2004 Feb; 18(3):290-305. PubMed ID: 14871928
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Delayed bone age due to a dual effect of FGFR3 mutation in Achondroplasia.
    Pannier S; Mugniery E; Jonquoy A; Benoist-Lasselin C; Odent T; Jais JP; Munnich A; Legeai-Mallet L
    Bone; 2010 Nov; 47(5):905-15. PubMed ID: 20673820
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A common FGFR3 gene mutation is present in achondroplasia but not in hypochondroplasia.
    Stoilov I; Kilpatrick MW; Tsipouras P
    Am J Med Genet; 1995 Jan; 55(1):127-33. PubMed ID: 7702086
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Achondroplasia in Turkey is defined by recurrent G380R mutation of the FGFR3 gene.
    Pehlivan S; Ozkinay F; Okutman O; Coğulu O; Ozcan A; Cankaya T; Ulgenalp A
    Turk J Pediatr; 2003; 45(2):99-101. PubMed ID: 12921294
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Activation of Stat1 by mutant fibroblast growth-factor receptor in thanatophoric dysplasia type II dwarfism.
    Su WC; Kitagawa M; Xue N; Xie B; Garofalo S; Cho J; Deng C; Horton WA; Fu XY
    Nature; 1997 Mar; 386(6622):288-92. PubMed ID: 9069288
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Mutations in the gene encoding fibroblast growth factor receptor-3 in achondroplasia.
    Rousseau F; Bonaventure J; Legeai-Mallet L; Pelet A; Rozet JM; Maroteaux P; Le Merrer M; Munnich A
    Nature; 1994 Sep; 371(6494):252-4. PubMed ID: 8078586
    [TBL] [Abstract][Full Text] [Related]  

  • 12. FGF upregulates osteopontin in epiphyseal growth plate chondrocytes: implications for endochondral ossification.
    Weizmann S; Tong A; Reich A; Genina O; Yayon A; Monsonego-Ornan E
    Matrix Biol; 2005 Dec; 24(8):520-9. PubMed ID: 16253490
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Constitutive activation of fibroblast growth factor receptor 3 by the transmembrane domain point mutation found in achondroplasia.
    Webster MK; Donoghue DJ
    EMBO J; 1996 Feb; 15(3):520-7. PubMed ID: 8599935
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Differential activation of cysteine-substitution mutants of fibroblast growth factor receptor 3 is determined by cysteine localization.
    Adar R; Monsonego-Ornan E; David P; Yayon A
    J Bone Miner Res; 2002 May; 17(5):860-8. PubMed ID: 12009017
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Reduced chondrocyte proliferation and chondrodysplasia in mice lacking the integrin-linked kinase in chondrocytes.
    Terpstra L; Prud'homme J; Arabian A; Takeda S; Karsenty G; Dedhar S; St-Arnaud R
    J Cell Biol; 2003 Jul; 162(1):139-48. PubMed ID: 12835312
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Skeletal dysplasia and defective chondrocyte differentiation by targeted overexpression of fibroblast growth factor 9 in transgenic mice.
    Garofalo S; Kliger-Spatz M; Cooke JL; Wolstin O; Lunstrum GP; Moshkovitz SM; Horton WA; Yayon A
    J Bone Miner Res; 1999 Nov; 14(11):1909-15. PubMed ID: 10571691
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A Ser(365)-->Cys mutation of fibroblast growth factor receptor 3 in mouse downregulates Ihh/PTHrP signals and causes severe achondroplasia.
    Chen L; Li C; Qiao W; Xu X; Deng C
    Hum Mol Genet; 2001 Mar; 10(5):457-65. PubMed ID: 11181569
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Clinical and molecular characteristics of Thai patients with achondroplasia.
    Shotelersuk V; Ittiwut C; Srivuthana S; Wacharasindhu S; Aroonparkmongkol S; Mutirangura A; Poovorawan Y
    Southeast Asian J Trop Med Public Health; 2001 Jun; 32(2):429-33. PubMed ID: 11556601
    [TBL] [Abstract][Full Text] [Related]  

  • 19. PTH has the potential to rescue disturbed bone growth in achondroplasia.
    Ueda K; Yamanaka Y; Harada D; Yamagami E; Tanaka H; Seino Y
    Bone; 2007 Jul; 41(1):13-8. PubMed ID: 17466614
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Reduced binding of FGF1 to mutant fibroblast growth factor receptor 3.
    Khnykin D; Olsnes S
    Growth Factors; 2006 Jun; 24(2):111-9. PubMed ID: 16801131
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.