BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

448 related articles for article (PubMed ID: 10646609)

  • 1. Cbl-b regulates the CD28 dependence of T-cell activation.
    Chiang YJ; Kole HK; Brown K; Naramura M; Fukuhara S; Hu RJ; Jang IK; Gutkind JS; Shevach E; Gu H
    Nature; 2000 Jan; 403(6766):216-20. PubMed ID: 10646609
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Negative regulation of lymphocyte activation and autoimmunity by the molecular adaptor Cbl-b.
    Bachmaier K; Krawczyk C; Kozieradzki I; Kong YY; Sasaki T; Oliveira-dos-Santos A; Mariathasan S; Bouchard D; Wakeham A; Itie A; Le J; Ohashi PS; Sarosi I; Nishina H; Lipkowitz S; Penninger JM
    Nature; 2000 Jan; 403(6766):211-6. PubMed ID: 10646608
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Cbl-b is a negative regulator of receptor clustering and raft aggregation in T cells.
    Krawczyk C; Bachmaier K; Sasaki T; Jones RG; Snapper SB; Bouchard D; Kozieradzki I; Ohashi PS; Alt FW; Penninger JM
    Immunity; 2000 Oct; 13(4):463-73. PubMed ID: 11070165
    [TBL] [Abstract][Full Text] [Related]  

  • 4. TCR and CD28 are coupled via ZAP-70 to the activation of the Vav/Rac-1-/PAK-1/p38 MAPK signaling pathway.
    Salojin KV; Zhang J; Delovitch TL
    J Immunol; 1999 Jul; 163(2):844-53. PubMed ID: 10395678
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Cutting edge: regulation of T cell activation threshold by CD28 costimulation through targeting Cbl-b for ubiquitination.
    Zhang J; Bárdos T; Li D; Gál I; Vermes C; Xu J; Mikecz K; Finnegan A; Lipkowitz S; Glant TT
    J Immunol; 2002 Sep; 169(5):2236-40. PubMed ID: 12193687
    [TBL] [Abstract][Full Text] [Related]  

  • 6. ZAP-70 and SLP-76 regulate protein kinase C-theta and NF-kappa B activation in response to engagement of CD3 and CD28.
    Herndon TM; Shan XC; Tsokos GC; Wange RL
    J Immunol; 2001 May; 166(9):5654-64. PubMed ID: 11313406
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Cbl-b negatively regulates B cell antigen receptor signaling in mature B cells through ubiquitination of the tyrosine kinase Syk.
    Sohn HW; Gu H; Pierce SK
    J Exp Med; 2003 Jun; 197(11):1511-24. PubMed ID: 12771181
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Proteolysis-independent regulation of PI3K by Cbl-b-mediated ubiquitination in T cells.
    Fang D; Liu YC
    Nat Immunol; 2001 Sep; 2(9):870-5. PubMed ID: 11526404
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Lymphocyte signaling: Cbl sets the threshold for autoimmunity.
    Rudd CE; Schneider H
    Curr Biol; 2000 May; 10(9):R344-7. PubMed ID: 10801434
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Impaired plasma membrane targeting of Grb2-murine son of sevenless (mSOS) complex and differential activation of the Fyn-T cell receptor (TCR)-zeta-Cbl pathway mediate T cell hyporesponsiveness in autoimmune nonobese diabetic mice.
    Salojin K; Zhang J; Cameron M; Gill B; Arreaza G; Ochi A; Delovitch TL
    J Exp Med; 1997 Sep; 186(6):887-97. PubMed ID: 9294143
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Activation of the Ras-related GTPase Rap1 by thymocyte TCR engagement and during selection.
    Amsen D; Kruisbeek A; Bos JL; Reedquist K
    Eur J Immunol; 2000 Oct; 30(10):2832-41. PubMed ID: 11069064
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Molecular controls of antigen receptor clustering and autoimmunity.
    Krawczyk C; Penninger JM
    Trends Cell Biol; 2001 May; 11(5):212-20. PubMed ID: 11316610
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A direct interaction between the adaptor protein Cbl-b and the kinase zap-70 induces a positive signal in T cells.
    Zhang Z; Elly C; Qiu L; Altman A; Liu YC
    Curr Biol; 1999 Feb; 9(4):203-6. PubMed ID: 10074432
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Perturbed regulation of ZAP-70 and sustained tyrosine phosphorylation of LAT and SLP-76 in c-Cbl-deficient thymocytes.
    Thien CB; Bowtell DD; Langdon WY
    J Immunol; 1999 Jun; 162(12):7133-9. PubMed ID: 10358158
    [TBL] [Abstract][Full Text] [Related]  

  • 15. CD28 signaling via VAV/SLP-76 adaptors: regulation of cytokine transcription independent of TCR ligation.
    Raab M; Pfister S; Rudd CE
    Immunity; 2001 Dec; 15(6):921-33. PubMed ID: 11754814
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Proto-oncoprotein Vav interacts with c-Cbl in activated thymocytes and peripheral T cells.
    Marengère LE; Mirtsos C; Kozieradzki I; Veillette A; Mak TW; Penninger JM
    J Immunol; 1997 Jul; 159(1):70-6. PubMed ID: 9200440
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Maintenance of human T cell anergy: blocking of IL-2 gene transcription by activated Rap1.
    Boussiotis VA; Freeman GJ; Berezovskaya A; Barber DL; Nadler LM
    Science; 1997 Oct; 278(5335):124-8. PubMed ID: 9311917
    [TBL] [Abstract][Full Text] [Related]  

  • 18. c-Cbl and Cbl-b regulate T cell responsiveness by promoting ligand-induced TCR down-modulation.
    Naramura M; Jang IK; Kole H; Huang F; Haines D; Gu H
    Nat Immunol; 2002 Dec; 3(12):1192-9. PubMed ID: 12415267
    [TBL] [Abstract][Full Text] [Related]  

  • 19. CD28 co-stimulation restores T cell responsiveness in NOD mice by overcoming deficiencies in Rac-1/p38 mitogen-activated protein kinase signaling and IL-2 and IL-4 gene transcription.
    Zhang J; Salojin KV; Delovitch TL
    Int Immunol; 2001 Mar; 13(3):377-84. PubMed ID: 11222507
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Fyn and ZAP-70 are required for Vav phosphorylation in T cells stimulated by antigen-presenting cells.
    Michel F; Grimaud L; Tuosto L; Acuto O
    J Biol Chem; 1998 Nov; 273(48):31932-8. PubMed ID: 9822663
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 23.