These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

69 related articles for article (PubMed ID: 10647504)

  • 1. Variability of cyclophosphamide uptake into human bronchial carcinoma: consequences for local bioactivation.
    Bohnenstengel F; Friedel G; Ritter CA; McClellan M; Fritz P; Eichelbaum M; Linder A; Toomes H; Dierkesmann R; Kroemer HK
    Cancer Chemother Pharmacol; 2000; 45(1):63-8. PubMed ID: 10647504
    [TBL] [Abstract][Full Text] [Related]  

  • 2. [Pharmacokinetics of cyclophosphamide, adriamycin and adriamycin prodrug (HMR 1928) using an ex vivo isolated perfused human lung model (IHLP)].
    Mürdter TE; Linder A; Friedel G; McClellan M; Bohnenstengel F; Sperker B; Kroemer HK; Toomes H; Freitag L; Fritz P
    Pneumologie; 2000 Nov; 54(11):494-8. PubMed ID: 11132546
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Enhanced uptake of doxorubicin into bronchial carcinoma: beta-glucuronidase mediates release of doxorubicin from a glucuronide prodrug (HMR 1826) at the tumor site.
    Mürdter TE; Sperker B; Kivistö KT; McClellan M; Fritz P; Friedel G; Linder A; Bosslet K; Toomes H; Dierkesmann R; Kroemer HK
    Cancer Res; 1997 Jun; 57(12):2440-5. PubMed ID: 9192823
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Fractionated administration of high-dose cyclophosphamide: influence on dose-dependent changes in pharmacokinetics and metabolism.
    Busse D; Busch FW; Schweizer E; Bohnenstengel F; Eichelbaum M; Fischer P; Schumacher K; Aulitzky WE; Kroemer HK
    Cancer Chemother Pharmacol; 1999; 43(3):263-8. PubMed ID: 9923558
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Pharmacokinetics of isolated lung perfusion with melphalan for resectable pulmonary metastases, a phase I and extension trial.
    Grootenboers MJ; Hendriks JM; van Boven WJ; Knibbe CA; van Putte B; Stockman B; De Bruijn E; Vermorken JB; Van Schil PE; Schramel FM
    J Surg Oncol; 2007 Dec; 96(7):583-9. PubMed ID: 17999399
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Dose optimization of a doxorubicin prodrug (HMR 1826) in isolated perfused human lungs: low tumor pH promotes prodrug activation by beta-glucuronidase.
    Mürdter TE; Friedel G; Backman JT; McClellan M; Schick M; Gerken M; Bosslet K; Fritz P; Toomes H; Kroemer HK; Sperker B
    J Pharmacol Exp Ther; 2002 Apr; 301(1):223-8. PubMed ID: 11907177
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Sustained P450 expression and prodrug activation in bolus cyclophosphamide-treated cultured tumor cells. Impact of prodrug schedule on P450 gene-directed enzyme prodrug therapy.
    Schwartz PS; Chen CS; Waxman DJ
    Cancer Gene Ther; 2003 Aug; 10(8):571-82. PubMed ID: 12872138
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Dose escalation of cyclophosphamide in patients with breast cancer: consequences for pharmacokinetics and metabolism.
    Busse D; Busch FW; Bohnenstengel F; Eichelbaum M; Fischer P; Opalinska J; Schumacher K; Schweizer E; Kroemer HK
    J Clin Oncol; 1997 May; 15(5):1885-96. PubMed ID: 9164199
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Frequent, moderate-dose cyclophosphamide administration improves the efficacy of cytochrome P-450/cytochrome P-450 reductase-based cancer gene therapy.
    Jounaidi Y; Waxman DJ
    Cancer Res; 2001 Jun; 61(11):4437-44. PubMed ID: 11389073
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Prodrug bioactivation and oncolysis of diffuse liver metastases by a herpes simplex virus 1 mutant that expresses the CYP2B1 transgene.
    Pawlik TM; Nakamura H; Mullen JT; Kasuya H; Yoon SS; Chandrasekhar S; Chiocca EA; Tanabe KK
    Cancer; 2002 Sep; 95(5):1171-81. PubMed ID: 12209705
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Enhanced cyclophosphamide and ifosfamide activation in primary human hepatocyte cultures: response to cytochrome P-450 inducers and autoinduction by oxazaphosphorines.
    Chang TK; Yu L; Maurel P; Waxman DJ
    Cancer Res; 1997 May; 57(10):1946-54. PubMed ID: 9157990
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Intratumoral activation and enhanced chemotherapeutic effect of oxazaphosphorines following cytochrome P-450 gene transfer: development of a combined chemotherapy/cancer gene therapy strategy.
    Chen L; Waxman DJ
    Cancer Res; 1995 Feb; 55(3):581-9. PubMed ID: 7834628
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Intraneoplastic polymer-based delivery of cyclophosphamide for intratumoral bioconversion by a replicating oncolytic viral vector.
    Ichikawa T; Petros WP; Ludeman SM; Fangmeier J; Hochberg FH; Colvin OM; Chiocca EA
    Cancer Res; 2001 Feb; 61(3):864-8. PubMed ID: 11221871
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Modulation of cyclophosphamide-based cytochrome P450 gene therapy using liver P450 inhibitors.
    Huang Z; Waxman DJ
    Cancer Gene Ther; 2001 Jun; 8(6):450-8. PubMed ID: 11498765
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Cyclophosphamide and 4-Hydroxycyclophosphamide/aldophosphamide kinetics in patients receiving high-dose cyclophosphamide chemotherapy.
    Anderson LW; Chen TL; Colvin OM; Grochow LB; Collins JM; Kennedy MJ; Strong JM
    Clin Cancer Res; 1996 Sep; 2(9):1481-7. PubMed ID: 9816324
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Enkephalin, its precursor, processing enzymes, and receptor as part of a local opioid network throughout the respiratory system of lung cancer patients.
    Krajnik M; Schäfer M; Sobanski P; Kowalewski J; Bloch-Boguslawska E; Zylicz Z; Mousa SA
    Hum Pathol; 2010 May; 41(5):632-42. PubMed ID: 20040394
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The ex-vivo isolated, perfused human lung model: description and potential applications.
    Linder A; Friedel G; Fritz P; Kivistö KT; McClellan M; Toomes H
    Thorac Cardiovasc Surg; 1996 Jun; 44(3):140-6. PubMed ID: 8858797
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Regional differences of melphalan lung levels after isolated lung perfusion in the rat.
    Romijn S; Hendriks JM; Van Putte BP; Weyler J; Guetens G; De Boeck G; Van Schil PE
    J Surg Res; 2005 May; 125(2):157-60. PubMed ID: 15854668
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Sensitization of human breast cancer cells to cyclophosphamide and ifosfamide by transfer of a liver cytochrome P450 gene.
    Chen L; Waxman DJ; Chen D; Kufe DW
    Cancer Res; 1996 Mar; 56(6):1331-40. PubMed ID: 8640822
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Impact of liver P450 reductase suppression on cyclophosphamide activation, pharmacokinetics and antitumoral activity in a cytochrome P450-based cancer gene therapy model.
    Huang Z; Raychowdhury MK; Waxman DJ
    Cancer Gene Ther; 2000 Jul; 7(7):1034-42. PubMed ID: 10917206
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 4.