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6. Suppression of transcription factor PDX-1/IPF1/STF-1/IDX-1 causes no decrease in insulin mRNA in MIN6 cells. Kajimoto Y; Watada H; Matsuoka Ta; Kaneto H; Fujitani Y; Miyazaki J; Yamasaki Y J Clin Invest; 1997 Oct; 100(7):1840-6. PubMed ID: 9312185 [TBL] [Abstract][Full Text] [Related]
7. Prevention of glucose toxicity in HIT-T15 cells and Zucker diabetic fatty rats by antioxidants. Tanaka Y; Gleason CE; Tran PO; Harmon JS; Robertson RP Proc Natl Acad Sci U S A; 1999 Sep; 96(19):10857-62. PubMed ID: 10485916 [TBL] [Abstract][Full Text] [Related]
8. Altered expression of HES-1, BETA2/NeuroD, and PDX-1 is involved in impaired insulin synthesis induced by glucocorticoids in HIT-T15 cells. Shinozuka Y; Okada M; Oki T; Sagane K; Mizui Y; Tanaka I; Katayama K; Murakami-Murofushi K Biochem Biophys Res Commun; 2001 Sep; 287(1):229-35. PubMed ID: 11549279 [TBL] [Abstract][Full Text] [Related]
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12. Differentiation of glucose toxicity from beta cell exhaustion during the evolution of defective insulin gene expression in the pancreatic islet cell line, HIT-T15. Moran A; Zhang HJ; Olson LK; Harmon JS; Poitout V; Robertson RP J Clin Invest; 1997 Feb; 99(3):534-9. PubMed ID: 9022089 [TBL] [Abstract][Full Text] [Related]
13. Chronic exposure of betaTC-6 cells to supraphysiologic concentrations of glucose decreases binding of the RIPE3b1 insulin gene transcription activator. Poitout V; Olson LK; Robertson RP J Clin Invest; 1996 Feb; 97(4):1041-6. PubMed ID: 8613527 [TBL] [Abstract][Full Text] [Related]
14. Glucose rapidly and reversibly decreases INS-1 cell insulin gene transcription via decrements in STF-1 and C1 activator transcription factor activity. Olson LK; Qian J; Poitout V Mol Endocrinol; 1998 Feb; 12(2):207-19. PubMed ID: 9482663 [TBL] [Abstract][Full Text] [Related]
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16. Multiple elements in the upstream glucokinase promoter contribute to transcription in insulinoma cells. Shelton KD; Franklin AJ; Khoor A; Beechem J; Magnuson MA Mol Cell Biol; 1992 Oct; 12(10):4578-89. PubMed ID: 1406648 [TBL] [Abstract][Full Text] [Related]
17. Reduction of insulin gene transcription in HIT-T15 beta cells chronically exposed to a supraphysiologic glucose concentration is associated with loss of STF-1 transcription factor expression. Olson LK; Sharma A; Peshavaria M; Wright CV; Towle HC; Rodertson RP; Stein R Proc Natl Acad Sci U S A; 1995 Sep; 92(20):9127-31. PubMed ID: 7568086 [TBL] [Abstract][Full Text] [Related]
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20. Effect of retinoic acid on glucokinase activity and gene expression and on insulin secretion in primary cultures of pancreatic islets. Cabrera-Valladares G; German MS; Matschinsky FM; Wang J; Fernandez-Mejia C Endocrinology; 1999 Jul; 140(7):3091-6. PubMed ID: 10385401 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]