389 related articles for article (PubMed ID: 10658585)
1. Synthesis and anti-HIV activity of 1,1,3-trioxo-2H,4H-thieno[3,4-e][1,2,4]thiadiazines (TTDs): a new family of HIV-1 specific non-nucleoside reverse transcriptase inhibitors.
Arranz ME; Díaz JA; Ingate ST; Witvrouw M; Pannecouque C; Balzarini J; De Clercq E; Vega S
Bioorg Med Chem; 1999 Dec; 7(12):2811-22. PubMed ID: 10658585
[TBL] [Abstract][Full Text] [Related]
2. 1,1,3-Trioxo-2H,4H-thieno[3,4-e][1,2,4]thiadiazine (TTD) derivatives: a new class of nonnucleoside human immunodeficiency virus type 1 (HIV-1) reverse transcriptase inhibitors with anti-HIV-1 activity.
Witvrouw M; Arranz ME; Pannecouque C; Declercq R; Jonckheere H; Schmit JC; Vandamme AM; Diaz JA; Ingate ST; Desmyter J; Esnouf R; Van Meervelt L; Vega S; Balzarini J; De Clercq E
Antimicrob Agents Chemother; 1998 Mar; 42(3):618-23. PubMed ID: 9517942
[TBL] [Abstract][Full Text] [Related]
3. Novel 1,1,3-trioxo-2H,4H-thieno[3,4-e][1,2,4]thiadiazine derivatives as non-nucleoside reverse transcriptase inhibitors that inhibit human immunodeficiency virus type 1 replication.
Arranz E; Díaz JA; Ingate ST; Witvrouw M; Pannecouque C; Balzarini J; De Clercq E; Vega S
J Med Chem; 1998 Oct; 41(21):4109-17. PubMed ID: 9767646
[TBL] [Abstract][Full Text] [Related]
4. Synthesis and studies of new 2-(coumarin-4-yloxy)-4,6-(substituted)-S-triazine derivatives as potential anti-HIV agents.
Mahajan DH; Pannecouque C; De Clercq E; Chikhalia KH
Arch Pharm (Weinheim); 2009 May; 342(5):281-90. PubMed ID: 19415671
[TBL] [Abstract][Full Text] [Related]
5. Pyrrolobenzoxazepinone derivatives as non-nucleoside HIV-1 RT inhibitors: further structure-activity relationship studies and identification of more potent broad-spectrum HIV-1 RT inhibitors with antiviral activity.
Campiani G; Morelli E; Fabbrini M; Nacci V; Greco G; Novellino E; Ramunno A; Maga G; Spadari S; Caliendo G; Bergamini A; Faggioli E; Uccella I; Bolacchi F; Marini S; Coletta M; Nacca A; Caccia S
J Med Chem; 1999 Oct; 42(21):4462-70. PubMed ID: 10543890
[TBL] [Abstract][Full Text] [Related]
6. Pyrido [1,2a] indole derivatives identified as novel non-nucleoside reverse transcriptase inhibitors of human immunodeficiency virus type 1.
Taylor DL; Ahmed PS; Chambers P; Tyms AS; Bedard J; Duchaine J; Falardeau G; Lavallée JF; Brown W; Rando RF; Bowlin T
Antivir Chem Chemother; 1999 Mar; 10(2):79-86. PubMed ID: 10335402
[TBL] [Abstract][Full Text] [Related]
7. Synthesis and biological evaluation of piperidine-substituted triazine derivatives as HIV-1 non-nucleoside reverse transcriptase inhibitors.
Chen X; Zhan P; Pannecouque C; Balzarini J; De Clercq E; Liu X
Eur J Med Chem; 2012 May; 51():60-6. PubMed ID: 22405288
[TBL] [Abstract][Full Text] [Related]
8. Discovery of novel indolylarylsulfones as potent HIV-1 NNRTIs via structure-guided scaffold morphing.
Zhao T; Meng Q; Kang D; Ji J; De Clercq E; Pannecouque C; Liu X; Zhan P
Eur J Med Chem; 2019 Nov; 182():111619. PubMed ID: 31434039
[TBL] [Abstract][Full Text] [Related]
9. Design, Synthesis, and Evaluation of Thiophene[3,2-d]pyrimidine Derivatives as HIV-1 Non-nucleoside Reverse Transcriptase Inhibitors with Significantly Improved Drug Resistance Profiles.
Kang D; Fang Z; Li Z; Huang B; Zhang H; Lu X; Xu H; Zhou Z; Ding X; Daelemans D; De Clercq E; Pannecouque C; Zhan P; Liu X
J Med Chem; 2016 Sep; 59(17):7991-8007. PubMed ID: 27541578
[TBL] [Abstract][Full Text] [Related]
10. 4-Benzyl and 4-benzoyl-3-dimethylaminopyridin-2(1H)-ones: in vitro evaluation of new C-3-amino-substituted and C-5,6-alkyl-substituted analogues against clinically important HIV mutant strains.
Benjahad A; Croisy M; Monneret C; Bisagni E; Mabire D; Coupa S; Poncelet A; Csoka I; Guillemont J; Meyer C; Andries K; Pauwels R; de Béthune MP; Himmel DM; Das K; Arnold E; Nguyen CH; Grierson DS
J Med Chem; 2005 Mar; 48(6):1948-64. PubMed ID: 15771439
[TBL] [Abstract][Full Text] [Related]
11. Structure-based design of non-nucleoside reverse transcriptase inhibitors of drug-resistant human immunodeficiency virus.
Mao C; Sudbeck EA; Venkatachalam TK; Uckun FM
Antivir Chem Chemother; 1999 Sep; 10(5):233-40. PubMed ID: 10574178
[TBL] [Abstract][Full Text] [Related]
12. Unique anti-human immunodeficiency virus activities of the nonnucleoside reverse transcriptase inhibitors calanolide A, costatolide, and dihydrocostatolide.
Buckheit RW; White EL; Fliakas-Boltz V; Russell J; Stup TL; Kinjerski TL; Osterling MC; Weigand A; Bader JP
Antimicrob Agents Chemother; 1999 Aug; 43(8):1827-34. PubMed ID: 10428899
[TBL] [Abstract][Full Text] [Related]
13. Discovery of biphenyl-substituted diarylpyrimidines as non-nucleoside reverse transcriptase inhibitors with high potency against wild-type and mutant HIV-1.
Jin K; Yin H; De Clercq E; Pannecouque C; Meng G; Chen F
Eur J Med Chem; 2018 Feb; 145():726-734. PubMed ID: 29353724
[TBL] [Abstract][Full Text] [Related]
14. Synthesis and anti-HIV evaluation of the novel 2-(m-chlorobenzyl)-4-substituted-7-methyl-1, 1, 3-trioxo-pyrazolo[4, 5-e] [1, 2, 4]thiadiazines.
Yan RZ; Liu XY; Xu WF; Pannecouque C; Witvrouw M; De Clercq E
Arch Pharm Res; 2006 Nov; 29(11):957-62. PubMed ID: 17146963
[TBL] [Abstract][Full Text] [Related]
15. Molecular design, synthesis and biological evaluation of BP-O-DAPY and O-DAPY derivatives as non-nucleoside HIV-1 reverse transcriptase inhibitors.
Yang S; Pannecouque C; Daelemans D; Ma XD; Liu Y; Chen FE; De Clercq E
Eur J Med Chem; 2013 Jul; 65():134-43. PubMed ID: 23707918
[TBL] [Abstract][Full Text] [Related]
16. Design, synthesis, and anti-HIV-1 activity of 1-aromatic methyl-substituted 3-(3,5-dimethylbenzyl)uracil and N-3,5-dimethylbenzyl-substituted urea derivatives.
Sakakibara N; Baba M; Okamoto M; Toyama M; Demizu Y; Misawa T; Kurihara M; Irie K; Kato Y; Maruyama T
Antivir Chem Chemother; 2015 Feb; 24(1):3-18. PubMed ID: 26149262
[TBL] [Abstract][Full Text] [Related]
17. Novel benzophenones as non-nucleoside reverse transcriptase inhibitors of HIV-1.
Chan JH; Freeman GA; Tidwell JH; Romines KR; Schaller LT; Cowan JR; Gonzales SS; Lowell GS; Andrews CW; Reynolds DJ; St Clair M; Hazen RJ; Ferris RG; Creech KL; Roberts GB; Short SA; Weaver K; Koszalka GW; Boone LR
J Med Chem; 2004 Feb; 47(5):1175-82. PubMed ID: 14971897
[TBL] [Abstract][Full Text] [Related]
18. Structural optimization of N
Monforte AM; De Luca L; Buemi MR; Agharbaoui FE; Pannecouque C; Ferro S
Bioorg Med Chem; 2018 Feb; 26(3):661-674. PubMed ID: 29291935
[TBL] [Abstract][Full Text] [Related]
19. Bioisosterism-based design and enantiomeric profiling of chiral hydroxyl-substituted biphenyl-diarylpyrimidine nonnucleoside HIV-1 reverse transcriptase inhibitors.
Chen X; Ding L; Tao Y; Pannecouque C; De Clercq E; Zhuang C; Chen FE
Eur J Med Chem; 2020 Sep; 202():112549. PubMed ID: 32712537
[TBL] [Abstract][Full Text] [Related]
20. N-[2-(1-cyclohexenyl)ethyl]-N'-[2-(5-bromopyridyl)]-thiourea and N'-[2-(1-cyclohexenyl)ethyl]-N'-[2-(5-chloropyridyl)]-thiourea as potent inhibitors of multidrug-resistant human immunodeficiency virus-1.
Uckun FM; Mao C; Pendergrass S; Maher D; Zhu D; Tuel-Ahlgren L; Venkatachalam TK
Bioorg Med Chem Lett; 1999 Sep; 9(18):2721-6. PubMed ID: 10509923
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
