BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

177 related articles for article (PubMed ID: 10658607)

  • 1. Synthesis and histamine H3 receptor activity of 4-(n-alkyl)-1H-imidazoles and 4-(omega-phenylalkyl)-1H-imidazoles.
    De Esch IJ; Gaffar A; Menge WM; Timmerman H
    Bioorg Med Chem; 1999 Dec; 7(12):3003-9. PubMed ID: 10658607
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Homologs of histamine as histamine H3 receptor antagonists: a new potent and selective H3 antagonist, 4(5)-(5-aminopentyl)-1H-imidazole.
    Vollinga RC; Menge WM; Leurs R; Timmerman H
    J Med Chem; 1995 Jan; 38(2):266-71. PubMed ID: 7830269
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Development of FUB 181, a selective histamine H3-receptor antagonist of high oral in vivo potency with 4-(omega-(arylalkyloxy)alkyl)-1H-imidazole structure.
    Stark H; Hüls A; Ligneau X; Purand K; Pertz H; Arrang JM; Schwartz JC; Schunack W
    Arch Pharm (Weinheim); 1998 Jun; 331(6):211-8. PubMed ID: 9713254
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Non-imidazole histamine H3 ligands. Part I. Synthesis of 2-(1-piperazinyl)- and 2-(hexahydro-1H-1,4-diazepin-1-yl)benzothiazole derivatives as H3-antagonists with H1 blocking activities.
    Walczyński K; Guryn R; Zuiderveld OP; Timmerman H
    Farmaco; 1999 Oct; 54(10):684-94. PubMed ID: 10575738
    [TBL] [Abstract][Full Text] [Related]  

  • 5. 4-(omega-(alkyloxy)alkyl)-1H-imidazole derivatives as histamine H(3) receptor antagonists/agonists.
    Meier G; Krause M; Hüls A; Ligneau X; Pertz HH; Arrang JM; Ganellin CR; Schwartz JC; Schunack W; Stark H
    J Med Chem; 2004 May; 47(10):2678-87. PubMed ID: 15115409
    [TBL] [Abstract][Full Text] [Related]  

  • 6. 4-[(1H-imidazol-4-yl) methyl] benzamidines and benzylamidines: novel antagonists of the histamine H3 receptor.
    Aslanian R; Brown JE; Shih NY; wa Mutahi M; Green MJ; She S; Del Prado M; West R; Hey J
    Bioorg Med Chem Lett; 1998 Aug; 8(16):2263-8. PubMed ID: 9873525
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Novel histamine H(3)-receptor antagonists with carbonyl-substituted 4-(3-(phenoxy)propyl)-1H-imidazole structures like ciproxifan and related compounds.
    Stark H; Sadek B; Krause M; Hüls A; Ligneau X; Ganellin CR; Arrang JM; Schwartz JC; Schunack W
    J Med Chem; 2000 Oct; 43(21):3987-94. PubMed ID: 11052804
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Structure-activity relationships of new 1-substitutedmethyl-4-[5-(N-methyl-N-propylamino)pentyloxy]piperidines and selected 1-[(N-substituted-N-methyl)-3-propyloxy]-5-(N-methy-l-N-propyl)-pentanediamines as H3 -antagonists.
    Masłowska-Lipowicz I; Walczyński K
    Chem Biol Drug Des; 2014 Jan; 83(1):106-18. PubMed ID: 23957330
    [TBL] [Abstract][Full Text] [Related]  

  • 9. omega-(Imidazol-4-yl)alkane-1-sulfonamides: a new series of potent histamine H(3) receptor antagonists.
    Tozer MJ; Buck IM; Cooke T; Kalindjian SB; Pether MJ; Steel KI
    Bioorg Med Chem; 2002 Feb; 10(2):425-32. PubMed ID: 11741790
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Reduction of CYP450 inhibition in the 4-[(1H-imidazol-4-yl)methyl]piperidine series of histamine H3 receptor antagonists.
    Berlin M; Ting PC; Vaccaro WD; Aslanian R; McCormick KD; Lee JF; Albanese MM; Mutahi MW; Piwinski JJ; Shih NY; Duguma L; Solomon DM; Zhou W; Sher R; Favreau L; Bryant M; Korfmacher WA; Nardo C; West RE; Anthes JC; Williams SM; Wu RL; Susan She H; Rivelli MA; Corboz MR; Hey JA
    Bioorg Med Chem Lett; 2006 Feb; 16(4):989-94. PubMed ID: 16297617
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis and in vitro pharmacology of a series of new chiral histamine H3-receptor ligands: 2-(R and S)-Amino-3-(1H-imidazol-4(5)-yl)propyl ether derivatives.
    Kovalainen JT; Christiaans JA; Kotisaari S; Laitinen JT; Männistö PT; Tuomisto L; Gynther J
    J Med Chem; 1999 Apr; 42(7):1193-202. PubMed ID: 10197963
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Novel histamine H3 receptor antagonists based on the 4-[(1H-imidazol-4-yl)methyl]piperidine scaffold.
    Vaccaro WD; Sher R; Berlin M; Shih NY; Aslanian R; Schwerdt JH; McCormick KD; Piwinski JJ; West RE; Anthes JC; Williams SM; Wu RL; She HS; Rivelli MA; Mutter JC; Corboz MR; Hey JA; Favreau L
    Bioorg Med Chem Lett; 2006 Jan; 16(2):395-9. PubMed ID: 16246552
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Meta-substituted aryl(thio)ethers as potent partial agonists (or antagonists) for the histamine H3 receptor lacking a nitrogen atom in the side chain.
    Pelloux-Léon N; Fkyerat A; Piripitsi A; Tertiuk W; Schunack W; Stark H; Garbarg M; Ligneau X; Arrang JM; Schwartz JC; Ganellin CR
    J Med Chem; 2004 Jun; 47(12):3264-74. PubMed ID: 15163206
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Ligands of the histamine H3-receptor: new potent antagonists of the 2-thioimidazole type.
    Plazzi PV; Mor M; Bordi F; Silva C; Rivara S; Caretta A; Ballabeni V; Impicciatore M; Vitali T
    Farmaco; 1997 May; 52(5):295-302. PubMed ID: 9274000
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Design, synthesis, and structure-activity relationships of acetylene-based histamine H3 receptor antagonists.
    Ali SM; Tedford CE; Gregory R; Handley MK; Yates SL; Hirth WW; Phillips JG
    J Med Chem; 1999 Mar; 42(5):903-9. PubMed ID: 10072687
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Non-Imidazole Histamine H₃ Ligands. Part VII. Synthesis, In Vitro and In Vivo Characterization of 5-Substituted-2-thiazol-4-n-propylpiperazines.
    Guryn R; Staszewski M; Stasiak A; McNaught Flores D; Fogel WA; Leurs R; Walczyński K
    Molecules; 2018 Feb; 23(2):. PubMed ID: 29401659
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Novel H3 receptor antagonists. Sulfonamide homologs of histamine.
    Wolin R; Connolly M; Afonso A; Hey JA; She H; Rivelli MA; Willams SM; West RE
    Bioorg Med Chem Lett; 1998 Aug; 8(16):2157-62. PubMed ID: 9873505
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A novel series of (phenoxyalkyl)imidazoles as potent H3-receptor histamine antagonists.
    Ganellin CR; Fkyerat A; Bang-Andersen B; Athmani S; Tertiuk W; Garbarg M; Ligneau X; Schwartz JC
    J Med Chem; 1996 Sep; 39(19):3806-13. PubMed ID: 8809168
    [TBL] [Abstract][Full Text] [Related]  

  • 19. New histamine H(3)-receptor ligands of the proxifan series: imoproxifan and other selective antagonists with high oral in vivo potency.
    Sasse A; Sadek B; Ligneau X; Elz S; Pertz HH; Luger P; Ganellin CR; Arrang JM; Schwartz JC; Schunack W; Stark H
    J Med Chem; 2000 Aug; 43(17):3335-43. PubMed ID: 10966752
    [TBL] [Abstract][Full Text] [Related]  

  • 20. 4-Alkynylphenyl imidazolylpropyl ethers as selective histamine H3-receptor antagonists with high oral central nervous system activity.
    Krause M; Ligneau X; Stark H; Garbarg M; Schwartz JC; Schunack W
    J Med Chem; 1998 Oct; 41(21):4171-6. PubMed ID: 9767653
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.